{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:58:47Z","timestamp":1789675127047,"version":"4.0.1"},"reference-count":102,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NDT"],"DOI":"10.2147\/ndt.s286977","type":"journal-article","created":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T21:48:34Z","timestamp":1607896114000},"page":"3081-3093","source":"Crossref","is-referenced-by-count":15,"title":["&lt;p&gt;The Long and Winding Road of Vagus Nerve Stimulation: Challenges in Developing an Intervention for Difficult-to-Treat Mood Disorders&lt;\/p&gt;"],"prefix":"10.2147","volume":"Volume 16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1107-4553","authenticated-orcid":true,"given":"Harold A","family":"Sackeim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxine","family":"Dibu\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark T","family":"Bunker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A John","family":"Rush","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.biopsych.2008.07.013","volume":"64","author":"George","year":"2008","journal-title":"Biol Psychiatry"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.brs.2016.03.010","volume":"9","author":"Perera","year":"2016","journal-title":"Brain Stimul"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"l1079","DOI":"10.1136\/bmj.l1079","volume":"364","author":"Mutz","year":"2019","journal-title":"BMJ"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"35","DOI":"10.4088\/JCP.16cs10905","volume":"79","author":"McClintock","year":"2018","journal-title":"J Clin Psychiatry"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1002\/da.21969","volume":"29","author":"Carpenter","year":"2012","journal-title":"Depress Anxiety"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.jad.2020.08.005","volume":"277","author":"Sackeim","year":"2020","journal-title":"J Affect Disord"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1001\/jamapsychiatry.2017.1670","volume":"74","author":"Sackeim","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1002\/da.22968","volume":"37","author":"Gaynes","year":"2020","journal-title":"Depress Anxiety"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1177\/0004867418808585","volume":"53","author":"Rush","year":"2019","journal-title":"Aust N Z J Psychiatry"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.jad.2020.02.023","volume":"267","author":"McAllister-Williams","year":"2020","journal-title":"J Affect Disord"},{"key":"ref11","volume-title":"Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease","year":"2017"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Working Group on Health Outcomes for Older Persons with Multiple Chronic Conditions. Universal health outcome measures for older persons with multiple chronic conditions. J Am Geriatr Soc. 2012;60(12):2333\u20132341. doi:10.1111\/j.1532-5415.2012.04240.x.","DOI":"10.1111\/j.1532-5415.2012.04240.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.18m12178","volume":"79","author":"Conway","year":"2018","journal-title":"J Clin Psychiatry"},{"key":"ref14","unstructured":"Food and Drug Administration. Summary of safety and effectiveness data (SSED) for vagus nerve stimulation in depression; July 13, 2020 [updated June 15, 2005]. Available from: https:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf\/p970003s207b.pdf. Accessed November 30, 2020."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.biopsych.2005.05.025","volume":"58","author":"Rush","year":"2005","journal-title":"Biol Psychiatry"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/s0006-3223(99)00304-2","volume":"47","author":"Rush","year":"2000","journal-title":"Biol Psychiatry"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/S0893-133X(01)00271-8","volume":"25","author":"Sackeim","year":"2001","journal-title":"Neuropsychopharmacology"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1176\/appi.ajp.2017.16010034","volume":"174","author":"Aaronson","year":"2017","journal-title":"Am J Psychiatry"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.comppsych.2019.152156","volume":"98","author":"Bottomley","year":"2020","journal-title":"Compr Psychiatry"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"17","DOI":"10.2147\/MDER.S41017","volume":"6","author":"Berry","year":"2013","journal-title":"Med Devices (Auckl)"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.1097\/YCT.0000000000000485","volume":"34","author":"Trottier-Duclos","year":"2018","journal-title":"J ECT"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1017\/S1461145706007425","volume":"10","author":"Sackeim","year":"2007","journal-title":"Int J Neuropsychopharmacol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.4088\/jcp.v66n0902","volume":"66","author":"Nahas","year":"2005","journal-title":"J Clin Psychiatry"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"457","DOI":"10.2147\/NDT.S196665","volume":"15","author":"Kumar","year":"2019","journal-title":"Neuropsychiatr Dis Treat"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00284","volume":"14","author":"Yap","year":"2020","journal-title":"Front Neurosci"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00854","volume":"13","author":"Kaniusas","year":"2019","journal-title":"Front Neurosci"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1007\/s00702-012-0908-6","volume":"120","author":"Hein","year":"2013","journal-title":"J Neural Transm"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.biopsych.2015.03.025","volume":"79","author":"Fang","year":"2016","journal-title":"Biol Psychiatry"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.jad.2016.02.031","volume":"195","author":"Rong","year":"2016","journal-title":"J Affect Disord"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/j.brs.2016.02.001","volume":"9","author":"Trevizol","year":"2016","journal-title":"Brain Stimul"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1111\/j.1528-1157.1990.tb05852.x","volume":"31","author":"Woodbury","year":"1990","journal-title":"Epilepsia"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1111\/j.1528-1157.1992.tb01751.x","volume":"33","author":"Zabara","year":"1992","journal-title":"Epilepsia"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"The Vagus Nerve Stimulation Study Group. A randomized controlled trial of chronic vagus nerve stimulation for treatment of medically intractable seizures. Neurology. 1995;45(2):224\u2013230. doi:10.1212\/wnl.45.2.224.","DOI":"10.1212\/WNL.45.2.224"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1212\/wnl.51.1.48","volume":"51","author":"Handforth","year":"1998","journal-title":"Neurology"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1212\/wnl.53.8.1731","volume":"53","author":"Morris","year":"1999","journal-title":"Neurology"},{"key":"ref36","first-page":"1301","volume":"18","author":"Sackeim","year":"1983","journal-title":"Biol Psychiatry"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1097\/00124509-199903000-00003","volume":"15","author":"Sackeim","year":"1999","journal-title":"J ECT"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000711","author":"Seymour","year":"2020","journal-title":"J ECT"},{"key":"ref39","first-page":"215","volume":"21","author":"Dunn","year":"1998","journal-title":"Clin Neuropharmacol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1017\/s1461145712000491","volume":"16","author":"Reinares","year":"2012","journal-title":"Int J Neuropsychopharmacol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.brs.2020.02.019","volume":"13","author":"Adair","year":"2020","journal-title":"Brain Stimul"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"108325","DOI":"10.1016\/j.jneumeth.2019.108325","volume":"325","author":"Thompson","year":"2019","journal-title":"J Neurosci Methods"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/cne.901610202","volume":"161","author":"Cottle","year":"1975","journal-title":"J Comp Neurol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0006-8993(78)91125-3","volume":"153","author":"Ricardo","year":"1978","journal-title":"Brain Res"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jpsychires.2003.11.005","volume":"38","author":"Krahl","year":"2004","journal-title":"J Psychiatr Res"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/s0920-1211(00)00181-9","volume":"42","author":"Elger","year":"2000","journal-title":"Epilepsy Res"},{"key":"ref47","first-page":"10","volume":"62","author":"Sackeim","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.jpsychires.2019.03.021","volume":"113","author":"Sackeim","year":"2019","journal-title":"J Psychiatr Res"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1017\/S0033291707001924","volume":"38","author":"Schlaepfer","year":"2008","journal-title":"Psychol Med"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1097\/JCP.0b013e3181db8831","volume":"30","author":"Bajbouj","year":"2010","journal-title":"J Clin Psychopharmacol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.biopsych.2005.07.028","volume":"58","author":"George","year":"2005","journal-title":"Biol Psychiatry"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/j.biopsych.2005.05.024","volume":"58","author":"Rush","year":"2005","journal-title":"Biol Psychiatry"},{"key":"ref53","unstructured":"Depression Guideline Panel. Depression in primary care: Vol.2. Treatment of major depression. U.S. Department of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, AHCPR. No. 93-0551; 1993."},{"key":"ref54","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1111\/j.1600-0404.2006.00732.x","volume":"115","author":"Labiner","year":"2007","journal-title":"Acta Neurol Scand"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1017\/S0033291700035558","volume":"26","author":"Rush","year":"1996","journal-title":"Psychol Med"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1192\/bjp.134.4.382","volume":"134","author":"Montgomery","year":"1979","journal-title":"Br J Psychiatry"},{"key":"ref57","doi-asserted-by":"crossref","unstructured":"Guy W ECDEU assessment manual for psychopharmacology. Superintendent of Documents, U.S. Government Printing Office, U.S. Department of Health, Education, and Welfare Publication, No. 76-338; 1976.","DOI":"10.1037\/e591322011-001"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"688","DOI":"10.4088\/JCP.v67n0501","volume":"67","author":"Dunner","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/0165-1781(87)90045-X","volume":"22","author":"Post","year":"1987","journal-title":"Psychiatry Res"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1001\/archpsyc.1986.01800090085011","volume":"43","author":"Roy-Byrne","year":"1986","journal-title":"Arch Gen Psychiatry"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1176\/ajp.2006.163.11.1905","volume":"163","author":"Rush","year":"2006","journal-title":"Am J Psychiatry"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1001\/jamapsychiatry.2016.2586","volume":"74","author":"Conway","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1176\/ajp.153.8.985","volume":"153","author":"Prudic","year":"1996","journal-title":"Am J Psychiatry"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/0165-1781(90)90098-P","volume":"31","author":"Prudic","year":"1990","journal-title":"Psychiatry Res"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1097\/JCP.0b013e3181ee0f5f","volume":"30","author":"Heijnen","year":"2010","journal-title":"J Clin Psychopharmacol"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1097\/00004714-199004000-00004","volume":"10","author":"Sackeim","year":"1990","journal-title":"J Clin Psychopharmacol"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1001\/archpsyc.57.5.425","volume":"57","author":"Sackeim","year":"2000","journal-title":"Arch Gen Psychiatry"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1001\/jama.285.10.1299","volume":"285","author":"Sackeim","year":"2001","journal-title":"JAMA"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/YCT.0b013e31826ea8c4","volume":"29","author":"Prudic","year":"2013","journal-title":"J ECT"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.brs.2016.03.006","volume":"9","author":"Sackeim","year":"2016","journal-title":"Brain Stimul"},{"key":"ref71","unstructured":"Schultz D VNS therapy system PMA approval for chronic or recurrent depression. FDA. Available from: https:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf\/P970003S050a.pdf. Accessed November 30, 2020."},{"key":"ref72","unstructured":"Centers for Medicare and Medicaid Services. National coverage determination (NCD) for vagus nerve stimulation (VNS) (160.18). CMS; 2007. Available from: https:\/\/www.cms.gov\/Regulations-and-Guidance\/Guidance\/Transmittals\/Downloads\/R70NCD.pdf. Accessed November 30, 2020."},{"key":"ref73","unstructured":"NICE (National Institue for Health and Clinical Excellence). Implanted vagus nerve stimulation for treatment-resistant depression (IPG679). National Clinical Practice Guideline. NICE; 2020."},{"key":"ref74","unstructured":"ANZHSN (Australai and New Zealand Horizon Scanning Network). National Horizon Scanning Unit Horizon Scanning Prioritising Summary: Update Number 3, VNS Therapy System for the Treatment of Depression. Adelaide Health Technology Assessment; 2007."},{"key":"ref75","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.brs.2012.09.013","volume":"6","author":"Aaronson","year":"2013","journal-title":"Brain Stimul"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1056\/NEJM199303253281204","volume":"328","author":"Sackeim","year":"1993","journal-title":"N Engl J Med"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1001\/archpsyc.57.5.438","volume":"57","author":"McCall","year":"2000","journal-title":"Arch Gen Psychiatry"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.brs.2008.03.001","volume":"1","author":"Sackeim","year":"2008","journal-title":"Brain Stimul"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"CD002896","DOI":"10.1002\/14651858.CD002896.pub2","volume":"4","author":"Panebianco","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1016\/j.biopsych.2007.01.018","volume":"62","author":"O\u2019Reardon","year":"2007","journal-title":"Biol Psychiatry"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1001\/archgenpsychiatry.2010.46","volume":"67","author":"George","year":"2010","journal-title":"Arch Gen Psychiatry"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1001\/archpsyc.1987.01800160067009","volume":"44","author":"Sackeim","year":"1987","journal-title":"Arch Gen Psychiatry"},{"key":"ref83","unstructured":"American Psychiatric Association. The Practice of ECT: Recommendations for Treatment, Training and Privileging. Second Edition. American Psychiatric Press; 2001."},{"key":"ref84","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.eurpsy.2011.07.006","volume":"27","author":"Martin","year":"2012","journal-title":"Eur Psychiatry"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jad.2008.02.012","volume":"110","author":"Daban","year":"2008","journal-title":"J Affect Disord"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"64","DOI":"10.3389\/fpsyg.2019.00064","volume":"10","author":"Lv","year":"2019","journal-title":"Front Psychol"},{"key":"ref87","unstructured":"Gaynes BN, Asher G, Gartlehner G, et al. Definition of treatment-resistant depression in the medicare population. AHRQ technology assessments; 2018. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30260611. Accessed November 30, 2020."},{"key":"ref88","unstructured":"Centers for Medicare and Medicaid Services. Decision memo for vagus nerve stimulation for treatment of resistant depression (TRD) (CAG-00313R). CMS; 2019. Available from: https:\/\/www.cms.gov\/medicare-coverage-database\/details\/nca-decision-memo.aspx?NCAId=292. Accessed November 30, 2020."},{"key":"ref89","doi-asserted-by":"publisher","first-page":"106066","DOI":"10.1016\/j.cct.2020.106066","volume":"95","author":"Conway","year":"2020","journal-title":"Contemp Clin Trials"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1176\/appi.ajp.2013.13030392","volume":"170","author":"Murrough","year":"2013","journal-title":"Am J Psychiatry"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1176\/appi.ajp.2018.17060720","volume":"175","author":"Canuso","year":"2018","journal-title":"Am J Psychiatry"},{"key":"ref92","first-page":"208","volume":"13","author":"Nobler","year":"1997","journal-title":"Convuls Ther"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1097\/YCT.0b013e31827e0b51","volume":"29","author":"Lapidus","year":"2013","journal-title":"J ECT"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3390\/ph3010019","volume":"3","author":"Machado-Vieira","year":"2010","journal-title":"Pharmaceuticals (Basel, Switzerland)"},{"key":"ref95","doi-asserted-by":"publisher","first-page":"CD012405","DOI":"10.1002\/14651858.CD012405.pub2","volume":"1","author":"Rodrigues","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"ref96","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/S1474-4422(20)30108-3","volume":"19","author":"Vitek","year":"2020","journal-title":"Lancet Neurol"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1212\/WNL.0000000000001334","volume":"84","author":"Salanova","year":"2015","journal-title":"Neurology"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1111\/j.1528-1167.2010.02536.x","volume":"51","author":"Fisher","year":"2010","journal-title":"Epilepsia"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1038\/s41398-019-0522-6","volume":"9","author":"Schruers","year":"2019","journal-title":"Transl Psychiatry"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1159\/000029018","volume":"31","author":"Paykel","year":"1998","journal-title":"Psychopathology"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1034\/j.1600-0447.106.s415.3.x","volume":"415","author":"Paykel","year":"2002","journal-title":"Acta Psychiatr Scand Suppl"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1002\/da.22103","volume":"30","author":"Bloch","year":"2013","journal-title":"Depress Anxiety"}],"container-title":["Neuropsychiatric Disease and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=64747","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=64747","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T21:48:47Z","timestamp":1607896127000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/the-long-and-winding-road-of-vagus-nerve-stimulation-challenges-in-dev-peer-reviewed-article-NDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":102,"URL":"https:\/\/doi.org\/10.2147\/ndt.s286977","relation":{},"ISSN":["1178-2021"],"issn-type":[{"value":"1178-2021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}