{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:22:43Z","timestamp":1777382563901,"version":"3.51.4"},"reference-count":58,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NDT"],"DOI":"10.2147\/ndt.s507851","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T11:45:11Z","timestamp":1742211911000},"page":"597-607","source":"Crossref","is-referenced-by-count":2,"title":["The Association Between Antidepressant Treatment and Heart Rate Deceleration Capacity in Patients With Mood disorders\u2014A Potential New Predictor of Sudden Cardiac Death"],"prefix":"10.2147","volume":"Volume 21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4206-307X","authenticated-orcid":true,"given":"Hiroaki","family":"Okayasu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7058-664X","authenticated-orcid":true,"given":"Norio","family":"Sugawara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumiko","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Ozeki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4414-3770","authenticated-orcid":true,"given":"Norio","family":"Yasui-Furukori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1097\/PSY.0000000000000382","volume":"79","author":"Shi","year":"2017","journal-title":"Psychosom Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.jad.2020.05.094","volume":"274","author":"Chen","year":"2020","journal-title":"J Affect Disord"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1517\/14740338.7.2.181","volume":"7","author":"Sicouri","year":"2008","journal-title":"Expert Opin Drug Saf"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1093\/eurheartj\/ehq438","volume":"32","author":"Hamer","year":"2011","journal-title":"Eur Heart J"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1016\/j.jacc.2008.10.060","volume":"53","author":"Whang","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"840452","DOI":"10.3389\/fcvm.2022.840452","volume":"9","author":"Cao","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e012503","DOI":"10.1161\/JAHA.119.012503","volume":"8","author":"Almuwaqqat","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/medsci9020026","volume":"9","author":"Prasitlumkum","year":"2021","journal-title":"Medical Sciences"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1016\/j.jacc.2005.08.067","volume":"47","author":"Straus","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1016\/S0140-6736(00)02035-3","volume":"355","author":"Reilly","year":"2000","journal-title":"Lancet"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"e441","DOI":"10.4088\/JCP.13r08672","volume":"75","author":"Beach","year":"2014","journal-title":"J Clin Psychiatry"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1111\/bcp.12681","volume":"80","author":"Maljuric","year":"2015","journal-title":"Br J Clin Pharmacol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1055\/s-0032-1308969","volume":"45","author":"Okayasu","year":"2012","journal-title":"Pharmacopsychiatry"},{"key":"ref14","unstructured":"ICH steering committee. Is. ICH harmonized tripartite guideline. The clinical evaluation of QT\/QTC interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs E14. 2025. Available from: https:\/\/database.ich.org\/sites\/default\/files\/E14_Guideline.pdf. Accessed November 11, 2024."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1097\/JCP.0b013e31823f6f21","volume":"32","author":"Watanabe","year":"2012","journal-title":"J Clin Psychopharmacol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1111\/j.1540-8167.2006.00408.x","volume":"17","author":"Goldenberg","year":"2006","journal-title":"J Cardiovasc Electrophysiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"473","DOI":"10.2165\/11587800-000000000-00000","volume":"25","author":"Nielsen","year":"2011","journal-title":"CNS Drugs"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.psym.2017.10.009","volume":"59","author":"Beach","year":"2018","journal-title":"Psychosomatics"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"166","DOI":"10.18632\/aging.101386","volume":"10","author":"Sessa","year":"2018","journal-title":"Aging (Albany NY)"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1161\/01.CIR.88.1.180","volume":"88","author":"Algra","year":"1993","journal-title":"Circulation"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"436","DOI":"10.7326\/0003-4819-118-6-199303150-00008","volume":"118","author":"van Ravenswaaij-Arts","year":"1993","journal-title":"Ann Intern Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1016\/0002-9149(91)90327-H","volume":"68","author":"Van Hoogenhuyze","year":"1991","journal-title":"Am J Cardiol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/0002-9149(88)90917-4","volume":"61","author":"Bigger","year":"1988","journal-title":"Am J Cardiol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1176\/appi.ajp.2014.13121605","volume":"171","author":"Kemp","year":"2014","journal-title":"Am J Psychiatry"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"258","DOI":"10.3389\/fpubh.2017.00258","volume":"5","author":"Shaffer","year":"2017","journal-title":"Front Public Health"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1016\/j.hrthm.2016.02.006","volume":"13","author":"Sammito","year":"2016","journal-title":"Heart Rhythm"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1053\/eupc.2001.0214","volume":"4","author":"Priori","year":"2002","journal-title":"Europace"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1016\/S0140-6736(06)68735-7","volume":"367","author":"Bauer","year":"2006","journal-title":"Lancet"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/s10840-008-9264-8","volume":"23","author":"Kreuz","year":"2008","journal-title":"J Interv Card Electrophysiol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1097\/00000542-200602000-00009","volume":"104","author":"Charbit","year":"2006","journal-title":"Anesthesiology"},{"key":"ref31","first-page":"353","volume":"7","author":"Bazet","year":"1920","journal-title":"Heart"},{"key":"ref32","first-page":"694","volume":"1","author":"Hodges","year":"1983","journal-title":"J Am Coll Cardiol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.jelectrocard.2004.08.030","volume":"37 Suppl","author":"Luo","year":"2004","journal-title":"J Electrocardiol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1111\/pcn.12275","volume":"69","author":"Inada","year":"2015","journal-title":"Psychiatry Clin Neurosci"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.clpt.2003.09.019","volume":"75","author":"Ray","year":"2004","journal-title":"Clin Pharmacol Ther"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.euroneuro.2023.03.013","volume":"71","author":"Fiani","year":"2023","journal-title":"Eur Neuropsychopharmacol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.genhosppsych.2023.01.005","volume":"81","author":"Okayasu","year":"2023","journal-title":"Gen Hosp Psychiatry"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"205","DOI":"10.2165\/00139709-200524030-00013","volume":"24","author":"Thanacoody","year":"2005","journal-title":"Toxicol Rev"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1038\/sj.bjp.0707253","volume":"151","author":"Gillman","year":"2007","journal-title":"Br J Pharmacol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1097\/00006842-197503000-00006","volume":"37","author":"Jefferson","year":"1975","journal-title":"Psychosom Med"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1016\/j.biopsych.2009.12.012","volume":"67","author":"Kemp","year":"2010","journal-title":"Biol Psychiatry"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1097\/WNF.0b013e3182a76fbb","volume":"36","author":"Terhardt","year":"2013","journal-title":"Clin Neuropharmacol"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.7573\/dic.2020-5-4","volume":"9","author":"Hedrick","year":"2020","journal-title":"Drugs Context"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"f288","DOI":"10.1136\/bmj.f288","volume":"346","author":"Castro","year":"2013","journal-title":"BMJ"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"190","DOI":"10.4088\/JCP.15m10324","volume":"78","author":"Ray","year":"2017","journal-title":"J Clin Psychiatry"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"E11","DOI":"10.1503\/jpn.130055","volume":"38","author":"Hasnain","year":"2013","journal-title":"J Psychiatry Neurosci"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1177\/1060028014550645","volume":"48","author":"Jasiak","year":"2014","journal-title":"Ann Pharmacother"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1001\/jamapsychiatry.2021.4313","volume":"79","author":"Henssler","year":"2022","journal-title":"JAMA Psychiatry"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1097\/JCP.0000000000000631","volume":"37","author":"Wu","year":"2017","journal-title":"J Clin Psychopharmacol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1097\/JCP.0000000000001189","volume":"40","author":"Biffi","year":"2020","journal-title":"J Clin Psychopharmacol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.eplepsyres.2007.12.020","volume":"79","author":"Hallioglu","year":"2008","journal-title":"Epilepsy Res"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1111\/j.1528-1167.2011.03361.x","volume":"53","author":"Lotufo","year":"2012","journal-title":"Epilepsia"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1111\/anec.12343","volume":"21","author":"Arsenos","year":"2016","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1161\/01.CIR.88.3.927","volume":"88","author":"Bigger","year":"1993","journal-title":"Circulation"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1111\/j.1540-8159.1996.tb03238.x","volume":"19","author":"Faber","year":"1996","journal-title":"Pacing Clin Electrophysiol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"111804","DOI":"10.1016\/j.jpsychores.2024.111804","volume":"182","author":"Ding","year":"2024","journal-title":"J Psychosom Res"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1111\/pcn.12178","volume":"68","author":"Chang","year":"2014","journal-title":"Psychiatry Clin Neurosci"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.jpsychires.2009.07.011","volume":"44","author":"Henry","year":"2010","journal-title":"J Psychiatr Res"}],"container-title":["Neuropsychiatric Disease and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/101223","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/101223","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T11:45:15Z","timestamp":1742211915000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/the-association-between-antidepressant-treatment-and-heart-rate-decele-peer-reviewed-fulltext-article-NDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":58,"URL":"https:\/\/doi.org\/10.2147\/ndt.s507851","relation":{},"ISSN":["1178-2021"],"issn-type":[{"value":"1178-2021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3]]}}}