{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T04:10:19Z","timestamp":1759896619364,"version":"build-2065373602"},"reference-count":55,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NDT"],"DOI":"10.2147\/ndt.s536528","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T03:50:11Z","timestamp":1759895411000},"page":"2279-2291","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy and Safety of Remote Ischemic Conditioning for Depression Insufficiently Responsive to Antidepressant: A Randomized Controlled Trial"],"prefix":"10.2147","volume":"Volume 21","author":[{"given":"Jun","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2104-6107","authenticated-orcid":true,"given":"Yu","family":"Shuai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ningning","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xujuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenfei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binxun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linlin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7295-196X","authenticated-orcid":true,"given":"Leping","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xunming","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1929-231X","authenticated-orcid":true,"given":"Zuowei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1177\/0706743716659416","volume":"61","author":"Lam","year":"2016","journal-title":"Can J Psychiatry"},{"key":"ref2","unstructured":"World Health Organization WHO. Depression and other common mental disorders.Global Health Estimates. Geneva:World Health Organization. Available from. https:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/igo\/. Accessed September 30, 2025."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S2215-0366(18)30511-X","volume":"6","author":"Huang","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1192\/bjp.bp.116.188078","volume":"210","author":"Thornicroft","year":"2017","journal-title":"Br J Psychiatry"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"2041","DOI":"10.1016\/S0140-6736(09)60660-7","volume":"373","author":"Phillips","year":"2009","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jad.2013.10.043","volume":"156","author":"McIntyre","year":"2014","journal-title":"J Affect Disord"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0197-2456(03)00112-0","volume":"25","author":"Rush","year":"2004","journal-title":"Control Clin Trials"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1176\/appi.ajp.163.1.28","volume":"163","author":"Trivedi","year":"2006","journal-title":"Am J Psychiatry"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1176\/ajp.2006.163.11.1905","volume":"163","author":"Rush","year":"2006","journal-title":"Am J Psychiatry"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1016\/S0140-6736(17)32802-7","volume":"391","author":"Andrea","year":"2018","journal-title":"Lancet"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1097\/YCO.00000000000000505","volume":"32","author":"Ormel","year":"2019","journal-title":"Curr Opin Psychiatry"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1001\/jamapsychiatry.2019.0633","volume":"76","author":"Jason","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1177\/0706743716659417","volume":"61","author":"Kennedy","year":"2016","journal-title":"Can J Psychiatry"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1177\/0706743716660033","volume":"61","author":"Milev","year":"2016","journal-title":"Can J Psychiatry"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1097\/JCP.0b013e3181ee0f5f","volume":"30","author":"Heijnen","year":"2010","journal-title":"J Clin Psychopharmacol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1186\/s13063-017-2125-y","volume":"18","author":"Mi","year":"2017","journal-title":"Trials"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1002\/wps.20199","volume":"14","author":"Levkovitz","year":"2015","journal-title":"World Psychiatry"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"570","DOI":"10.3389\/fpsyt.2020.00570","volume":"11","author":"Wang","year":"2020","journal-title":"Front Psychiatry"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"299","DOI":"10.6515\/ACS.201807_34(4).20180317A","volume":"34","author":"Xu","year":"2018","journal-title":"Acta Cardiol Sin"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"5361","DOI":"10.1038\/s41598-020-62336-w","volume":"10","author":"Lv","year":"2020","journal-title":"Sci Rep"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.12659\/msm.908247","volume":"24","author":"Cao","year":"2018","journal-title":"Med Sci Monit"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"467","DOI":"10.3389\/fneur.2019.00467","volume":"10","author":"You","year":"2019","journal-title":"Front Neurol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/S0166-2236(03)00071-7","volume":"26","author":"Dirnagl","year":"2003","journal-title":"Trends Neurosci"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1007\/s13311-015-0358-6","volume":"12","author":"Meng","year":"2015","journal-title":"Neurotherapeutics"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/nrcardio.2016.5","volume":"13","author":"Hausenloy","year":"2016","journal-title":"Nat Rev Cardiol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"369","DOI":"10.3233\/RNN-140413","volume":"33","author":"Ren","year":"2015","journal-title":"Restor Neurol Neurosci"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.bbr.2016.10.036","volume":"340","author":"Ren","year":"2018","journal-title":"Behav Brain Res"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.1212\/WNL.0b013e318271f76a","volume":"79","author":"Meng","year":"2012","journal-title":"Neurology"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.3727\/096368914X683520","volume":"24","author":"Li","year":"2015","journal-title":"Cell Transplant"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1161\/CIRCULATIONAHA.116.024807","volume":"135","author":"Zhao","year":"2017","journal-title":"Circulation"},{"key":"ref31","first-page":"CD012503","volume":"7","author":"Zhao","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"634","DOI":"10.18632\/aging.101764","volume":"11","author":"Zhou","year":"2019","journal-title":"Aging"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4088\/JCP.0208e04","volume":"69","author":"Nutt","year":"2008","journal-title":"J Clin Psychiatry"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.neuron.2020.06.002","volume":"107","author":"Beurel","year":"2020","journal-title":"Neuron"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s12264-014-1486-4","volume":"31","author":"Cai","year":"2015","journal-title":"Neurosci Bull"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"2283","DOI":"10.3390\/ijms20092283","volume":"20","author":"Milenkovic","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1136\/svn-2017-000119","volume":"3","author":"Etherton","year":"2018","journal-title":"Stroke Vasc Neurol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/s0006-3223(02)01866-8","volume":"54","author":"Rush","year":"2003","journal-title":"Biol. Psychiatry"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","volume":"16","author":"Kroenke","year":"2001","journal-title":"J Gen Intern Med"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1055\/s-0041-110203","volume":"83","author":"Roniger","year":"2015","journal-title":"Psychother Psychosomatics"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1056\/NEJMoa052964","volume":"354","author":"Trivedi","year":"2006","journal-title":"N Engl J Med"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s13063-016-1764-8","volume":"18","author":"Bulteau","year":"2017","journal-title":"Trials"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"17032","DOI":"10.3390\/ijms242317032","volume":"24","author":"Baranova","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"812","DOI":"10.3389\/fneur.2020.00812","volume":"11","author":"Hao","year":"2020","journal-title":"Front Neurol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1177\/17474930231191082","volume":"19","author":"Keevil","year":"2024","journal-title":"Int J Stroke"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1007\/s12035-021-02585-6","volume":"59","author":"Mollet","year":"2022","journal-title":"Vieira Mol Neurobiol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1124\/pharmrev.121.000348","volume":"75","author":"Ferdinandy","year":"2023","journal-title":"Pharmacol Rev"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"e0195507","DOI":"10.1371\/journal.pone.0195507","volume":"13","author":"Czigany","year":"2018","journal-title":"PLoS One"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"72","DOI":"10.17116\/jnevro201911906172","volume":"119","author":"Baranova","year":"2019","journal-title":"Zh Nevrol Psikhiatr Im S S Korsakova"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1134\/S1819712418020022","volume":"12","author":"Baranova","year":"2018","journal-title":"Neurochem J"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"104032","DOI":"10.1016\/j.ajp.2024.104032","volume":"96","author":"Lan","year":"2024","journal-title":"Asian J Psychiatr"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1097\/j.pain.0000000000003082","volume":"165","author":"Bouhassira","year":"2024","journal-title":"Pain"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.neubiorev.2017.10.006","volume":"83","author":"Valero-Cabr\u00e9","year":"2017","journal-title":"Neurosci Biobehav Rev"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.jad.2023.10.161","volume":"346","author":"Cai","year":"2024","journal-title":"J Affect Disord"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"1290364","DOI":"10.3389\/fpsyt.2023.1290364","volume":"14","author":"Lan","year":"2023","journal-title":"Front Psychiatry"}],"container-title":["Neuropsychiatric Disease and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/107684","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/107684","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T03:50:14Z","timestamp":1759895414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/efficacy-and-safety-of-remote-ischemic-conditioning-for-depression-ins-peer-reviewed-fulltext-article-NDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":55,"URL":"https:\/\/doi.org\/10.2147\/ndt.s536528","relation":{},"ISSN":["1178-2021"],"issn-type":[{"value":"1178-2021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]}}}