{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T13:07:46Z","timestamp":1752671266094,"version":"3.40.5"},"reference-count":18,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NSS"],"DOI":"10.2147\/nss.s350350","type":"journal-article","created":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T13:30:12Z","timestamp":1643895012000},"page":"175-178","source":"Crossref","is-referenced-by-count":2,"title":["S-Adenosylmethionine May Mitigate Obstructive Sleep Apnea in an Adult with Down Syndrome: A Case Report"],"prefix":"10.2147","volume":"Volume 14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1563-6864","authenticated-orcid":true,"given":"Silvano","family":"Dragonieri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna Elisiana","family":"Carpagnano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Caccamese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2022,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2147\/NSS.S124657","volume":"10","author":"Osman","year":"2018","journal-title":"Nat Sci Sleep"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"208","DOI":"10.3390\/medicina56050208","volume":"56","author":"Dragonieri","year":"2020","journal-title":"Medicina"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"15015","DOI":"10.1038\/nrdp.2015.15","volume":"1","author":"L\u00e9vy","year":"2015","journal-title":"Nat Rev Dis Primers"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41572-019-0143-7","volume":"6","author":"Antonarakis","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.smrv.2018.11.002","volume":"44","author":"Horne","year":"2019","journal-title":"Sleep Med Rev"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"899","DOI":"10.5664\/jcsm.8358","volume":"16","author":"Yu","year":"2020","journal-title":"J Clin Sleep Med"},{"key":"ref7","unstructured":"Lao PJ, Zimmerman ME, Gutierrez J, et al. Sleep apnea may be a modifiable target in the development of cerebrovascular disease and cortical amyloid in older adults with Down syndrome. 4th Trisomy 21 Research Society International Conference, Virtual; June 8\u201310; 2021."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1136\/thx.2006.069963","volume":"62","author":"Barreiro","year":"2007","journal-title":"Thorax"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1988","DOI":"10.1016\/S0140-6736(20)30689-9","volume":"395","author":"Fortea","year":"2020","journal-title":"Lancet"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1002\/alz.12112","volume":"16","author":"Snyder","year":"2020","journal-title":"Alzheimers Dement"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.ymgme.2010.11.166","volume":"102","author":"Infantino","year":"2011","journal-title":"Mol Genet Metab"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1007\/s13311-017-0593-0","volume":"15","author":"Gao","year":"2018","journal-title":"Neurotherapeutics"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"991","DOI":"10.3233\/JAD-151098","volume":"51","author":"Remington","year":"2016","journal-title":"J Alzheimers Dis"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/S1474-4422(16)30034-5","volume":"15","author":"De la Torre","year":"2016","journal-title":"Lancet Neurol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1016\/j.neubiorev.2016.10.023","volume":"71","author":"Vacca","year":"2016","journal-title":"Neurosci Biobehav Rev"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1378\/chest.14-2873","volume":"148","author":"Chervin","year":"2015","journal-title":"Chest"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.sleep.2016.11.024","volume":"32","author":"Slonkova","year":"2017","journal-title":"Sleep Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"549","DOI":"10.3233\/JAD-170177","volume":"58","author":"Li","year":"2017","journal-title":"J Alzheimers Dis"}],"container-title":["Nature and Science of Sleep"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=78054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=78054","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T13:30:15Z","timestamp":1643895015000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/s-adenosylmethionine-may-mitigate-obstructive-sleep-apnea-in-an-adult--peer-reviewed-fulltext-article-NSS"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":18,"URL":"https:\/\/doi.org\/10.2147\/nss.s350350","relation":{},"ISSN":["1179-1608"],"issn-type":[{"type":"electronic","value":"1179-1608"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}