{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:07:46Z","timestamp":1747206466828,"version":"3.40.5"},"reference-count":37,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OPTH"],"DOI":"10.2147\/opth.s275762","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T21:43:50Z","timestamp":1608673430000},"page":"4483-4492","source":"Crossref","is-referenced-by-count":5,"title":["Methylene Blue Inhibits Acute Hemorrhagic Conjunctivitis Virus Production and Induction of Caspase-3 Mediated Human Corneal Cell Cytopathy"],"prefix":"10.2147","volume":"Volume 14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8673-976X","authenticated-orcid":true,"given":"Marlyn P","family":"Langford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra R","family":"Sebren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxwell A","family":"Burch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas B","family":"Redens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.2147\/OPTH.S85358","volume":"9","author":"Langford","year":"2015","journal-title":"Clin Ophthalmol"},{"key":"ref2","first-page":"173","volume":"45","author":"Wright","year":"1992","journal-title":"Am Fam Physician"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1136\/bjo.74.2.89","volume":"74","author":"Babalola","year":"1990","journal-title":"Br J Ophthalmol"},{"key":"ref4","first-page":"244","volume":"27","author":"Kosrirukvongs","year":"1996","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.2147\/OPTH.S81386","volume":"9","author":"Harada","year":"2015","journal-title":"Clin Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.virol.2005.12.005","volume":"347","author":"Chen","year":"2006","journal-title":"Virology"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1093\/infdis\/139.6.653","volume":"139","author":"Langford","year":"1979","journal-title":"J Infect Dis"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1136\/bjo.54.9.628","volume":"54","author":"Chatterjee","year":"1970","journal-title":"Br J Ophthalmol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1016\/s0140-6736(72)90921-x","volume":"i","author":"Kono","year":"1972","journal-title":"Lancet"},{"key":"ref10","first-page":"1","volume":"8","author":"Chang","year":"1977","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1038\/s41598-019-56850-9","volume":"10","author":"Zhang","year":"2020","journal-title":"Sci Rep"},{"key":"ref12","unstructured":"Herriman R. Belize is the latest Central American country battling a \u2018pink eye\u2019 outbreak. Outbreak News Today, October 8, 2017. Available from: http:\/\/outbreaknewstoday.com\/belize-latest-central-american-country-battling-pink-eye-outbreak-31171\/. Accessed December 15, 2020."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1159\/000489339","volume":"60","author":"Enfissi","year":"2017","journal-title":"Intervirology"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1007\/s00705-019-04157-5","volume":"164","author":"Sousa","year":"2019","journal-title":"Arch Virol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1001\/jama.250.6.794","volume":"250","author":"Alfonso","year":"1983","journal-title":"JAMA"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1097\/00003226-199811000-00009","volume":"17","author":"Vajpayee","year":"1998","journal-title":"Cornea"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1515\/znb-1960-0909","volume":"15B","author":"Kovacs","year":"1960","journal-title":"Z Naturforsch B"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1167\/iovs.10-5801","volume":"52","author":"Pan","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1017\/S002217240002338X","volume":"72","author":"Nejmi","year":"1974","journal-title":"J Hyg"},{"key":"ref20","first-page":"245","volume":"34","author":"Ghafoor","year":"1984","journal-title":"J Pak Med Assoc"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1128\/IAI.41.2.631-635.1983","volume":"41","author":"Kew","year":"1983","journal-title":"Infect Immun"},{"key":"ref22","first-page":"1648","volume":"305","author":"Hatch","year":"1981","journal-title":"N Engl J Med"},{"key":"ref23","first-page":"23","volume":"29","author":"Yin-Murphy","year":"1984","journal-title":"Prog Med Virol"},{"key":"ref24","first-page":"355","volume":"7","author":"Bahrin","year":"1976","journal-title":"Southeast Asian J Trop Med Public Health"},{"volume-title":"Acute Hemorrhagic Conjunctivitis; Etiology, Epidemiology and Clinical Manifestations","year":"1989","key":"ref25"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1128\/IAI.18.2.370-376.1977","volume":"18","author":"Stanton","year":"1977","journal-title":"Infect Immun"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/0002-9394(61)90338-5","volume":"52","author":"De Ocampo","year":"1961","journal-title":"Am J Ophthalmol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"13730","DOI":"10.1038\/srep13730","volume":"5","author":"Pakavathkumar","year":"2015","journal-title":"Sci Rep"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"2176","DOI":"10.1093\/jac\/dkq301","volume":"65","author":"Wong","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.antiviral.2003.11.004","volume":"61","author":"Floyd","year":"2004","journal-title":"Antiviral Res"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1016\/j.freeradbiomed.2009.02.003","volume":"46","author":"Floyd","year":"2009","journal-title":"Free Radic Biol Med"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1159\/000054271","volume":"8","author":"Lomniczi","year":"2000","journal-title":"Neuroimmunomodulation"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"81014","DOI":"10.18632\/oncotarget.21250","volume":"8","author":"Dang","year":"2017","journal-title":"Oncotarget"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"81","DOI":"10.17116\/oftalma2016132581-85","volume":"132","author":"Marchenko","year":"2016","journal-title":"Vestn Oftalmol"},{"key":"ref35","first-page":"317","volume":"24","author":"Brownstein","year":"1989","journal-title":"Can J Ophthalmol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1097\/01.ico.0000183488.78012.33","volume":"25","author":"Brouzas","year":"2006","journal-title":"Cornea"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"5137","DOI":"10.1007\/s12035-017-0712-2","volume":"55","author":"Tucker","year":"2018","journal-title":"Mol Neurobiol"}],"container-title":["Clinical Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=65105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=65105","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T21:43:56Z","timestamp":1608673436000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/methylene-blue-inhibits-acute-hemorrhagic-conjunctivitis-virus-product-peer-reviewed-article-OPTH"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":37,"URL":"https:\/\/doi.org\/10.2147\/opth.s275762","relation":{},"ISSN":["1177-5483"],"issn-type":[{"type":"electronic","value":"1177-5483"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}