{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T16:42:51Z","timestamp":1767890571100,"version":"3.49.0"},"reference-count":61,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OPTH"],"DOI":"10.2147\/opth.s335197","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T17:55:34Z","timestamp":1636480534000},"page":"4419-4430","source":"Crossref","is-referenced-by-count":1,"title":["Characterization of Polybacterial versus Monobacterial Conjunctivitis Infections in Pediatric Subjects Across Multiple Studies and Microbiological Outcomes with Besifloxacin Ophthalmic Suspension 0.6%"],"prefix":"10.2147","volume":"Volume 15","author":[{"given":"Joseph M","family":"Blondeau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4278-2552","authenticated-orcid":true,"given":"Howard M","family":"Proskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine M","family":"Sanfilippo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3248-6896","authenticated-orcid":true,"given":"Heleen H","family":"DeCory","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2021,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/j.1600-0420.2007.01006.x","volume":"86","author":"Hovding","year":"2008","journal-title":"Acta Ophthalmol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1128\/AAC.44.6.1650-1654.2000","volume":"44","author":"Block","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1097\/01.inf.0000178066.24569.98","volume":"24","author":"Buznach","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/S0022-3476(05)83479-1","volume":"122","author":"Weiss","year":"1993","journal-title":"J Pediatr"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.1001\/jama.2013.280318","volume":"310","author":"Azari","year":"2013","journal-title":"JAMA"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/S0002-9394(99)00112-9","volume":"128","author":"Kunimoto","year":"1999","journal-title":"Am J Ophthalmol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/S0002-9394(99)00113-0","volume":"128","author":"Kunimoto","year":"1999","journal-title":"Am J Ophthalmol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1136\/bjo.87.7.834","volume":"87","author":"Bourcier","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1097\/ICL.0b013e3182a3024e","volume":"39","author":"Lim","year":"2013","journal-title":"Eye Contact Lens"},{"key":"ref10","first-page":"614","volume":"60","author":"Hooi","year":"2005","journal-title":"Med J Malaysia"},{"key":"ref11","first-page":"118","volume":"50","author":"Stefan","year":"2006","journal-title":"Oftalmologia"},{"key":"ref12","first-page":"737","volume":"90","author":"Preechawat","year":"2007","journal-title":"J Med Assoc Thai"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.jcjo.2017.11.001","volume":"53","author":"Termote","year":"2018","journal-title":"Can J Ophthalmol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1177\/112067210901900520","volume":"19","author":"Sowmya","year":"2009","journal-title":"Eur J Ophthalmol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2009.09.021","volume":"149","author":"Pijl","year":"2010","journal-title":"Am J Ophthalmol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"153","DOI":"10.4103\/0255-0857.180280","volume":"34","author":"Bhattacharjee","year":"2016","journal-title":"Indian J Med Microbiol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1136\/bjo.87.9.1103","volume":"87","author":"Wong","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e0237603","DOI":"10.1371\/journal.pone.0237603","volume":"15","author":"DeCory","year":"2020","journal-title":"PLoS One"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"e18570","DOI":"10.1097\/MD.0000000000018570","volume":"99","author":"Bhattacharyya","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"135","DOI":"10.3928\/01913913-20170718-01","volume":"55","author":"Hashish","year":"2018","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/S0140-6736(05)66709-8","volume":"366","author":"Rose","year":"2005","journal-title":"Lancet"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1185\/03007990902837919","volume":"25","author":"Tepedino","year":"2009","journal-title":"Curr Med Res Opin"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1016\/j.ophtha.2009.05.014","volume":"116","author":"McDonald","year":"2009","journal-title":"Ophthalmology"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.clinthera.2009.03.010","volume":"31","author":"Karpecki","year":"2009","journal-title":"Clin Ther"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"303","DOI":"10.2165\/11632470-000000000-00000","volume":"32","author":"DeLeon","year":"2012","journal-title":"Clin Drug Investig"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/s40268-013-0029-1","volume":"13","author":"Malhotra","year":"2013","journal-title":"Drugs R D"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.2147\/OPTH.S23519","volume":"5","author":"Haas","year":"2011","journal-title":"Clin Ophthalmol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"523","DOI":"10.3109\/02713688109069178","volume":"1","author":"Cagle","year":"1981","journal-title":"Curr Eye Res"},{"key":"ref29","first-page":"29S","volume":"112","author":"Leibowitz","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"ref30","unstructured":"Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; Approved standards. 6th ed. In: CLSI Document M07-A6. Wayne, PA: Clinical and Laboratory Standards Institute; 2003."},{"key":"ref31","unstructured":"Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; Approved standards. 7th ed. In: CLSI Document M07-A7. Wayne, PA: Clinical and Laboratory Standards Institute; 2006."},{"key":"ref32","unstructured":"Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; Approved standard. 8th ed. In: CLSI Document M07-A8. Wayne, PA: Clinical and Laboratory Standards Institute; 2009."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.1099\/jmm.0.000573","volume":"66","author":"Rasmussen","year":"2017","journal-title":"J Med Microbiol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1111\/j.2041-1014.2010.00601.x","volume":"26","author":"Mitchell","year":"2011","journal-title":"Mol Oral Microbiol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"3006","DOI":"10.3389\/fmicb.2019.03006","volume":"10","author":"Bair","year":"2020","journal-title":"Front Microbiol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1111\/2049-632X.12129","volume":"70","author":"Perez","year":"2014","journal-title":"Pathog Dis"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1016\/j.tim.2014.05.007","volume":"22","author":"Short","year":"2014","journal-title":"Trends Microbiol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0140-6736(05)70155-0","volume":"365","author":"Brogden","year":"2005","journal-title":"Lancet"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.jinf.2011.06.005","volume":"63","author":"Griffiths","year":"2011","journal-title":"J Infect"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"e000006","DOI":"10.1136\/bmjophth-2016-000006","volume":"1","author":"Silvester","year":"2016","journal-title":"BMJ Open Ophthalmol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3126\/nepjoph.v8i1.16153","volume":"8","author":"Shrestha","year":"2016","journal-title":"Nepal J Ophthalmol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"e0205814","DOI":"10.1371\/journal.pone.0205814","volume":"13","author":"Asbell","year":"2018","journal-title":"PLoS One"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1097\/INF.0000000000002206","volume":"38","author":"Alter","year":"2019","journal-title":"Pediatr Infect Dis J"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1001\/jamaophthalmol.2020.0155","volume":"138","author":"Asbell","year":"2020","journal-title":"JAMA Ophthalmol"},{"key":"ref45","unstructured":"Research and Markets. Global conjunctivitis drugs market 2018\u20132024. Available from: https:\/\/www.researchandmarkets.com\/research\/xx9d9p\/global?w=5. Accessed December 8, 2020."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"3552","DOI":"10.1128\/AAC.00418-09","volume":"53","author":"Haas","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.1093\/jac\/dkq127","volume":"65","author":"Haas","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"821","DOI":"10.2147\/OPTH.S44085","volume":"7","author":"Haas","year":"2013","journal-title":"Clin Ophthalmol"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1089\/jop.2012.0081","volume":"29","author":"Miller","year":"2013","journal-title":"J Ocul Pharmacol Ther"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1093\/jac\/dkn528","volume":"63","author":"Cambau","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s40123-016-0046-6","volume":"5","author":"Mah","year":"2016","journal-title":"Ophthalmol Ther"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1007\/s12275-014-4067-3","volume":"52","author":"Murray","year":"2014","journal-title":"J Microbiol"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"855","DOI":"10.2106\/00004623-200106000-00006","volume":"83","author":"Hendricks","year":"2001","journal-title":"J Bone Joint Surg Am"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"633","DOI":"10.2217\/fmb.13.26","volume":"8","author":"Bousbia","year":"2013","journal-title":"Future Microbiol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.tim.2012.11.005","volume":"21","author":"Shak","year":"2013","journal-title":"Trends Microbiol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"6141","DOI":"10.1007\/s00253-016-7596-3","volume":"100","author":"Nguyen","year":"2016","journal-title":"Appl Microbiol Biotechnol"},{"key":"ref57","first-page":"345","volume":"28","author":"Catalanotti","year":"2005","journal-title":"New Microbiol"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"233","DOI":"10.33073\/pjm-2010-036","volume":"59","author":"Murugan","year":"2010","journal-title":"Pol J Microbiol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"e0135964","DOI":"10.1371\/journal.pone.0135964","volume":"10","author":"Flores-P\u00e1ez","year":"2015","journal-title":"PLoS One"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1007\/s10792-016-0339-8","volume":"37","author":"Fari\u00f1a","year":"2017","journal-title":"Int Ophthalmol"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"309","DOI":"10.4103\/JLP.JLP_122_17","volume":"10","author":"Elkhashab","year":"2018","journal-title":"J Lab Physicians"}],"container-title":["Clinical Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=75694","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=75694","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T17:55:43Z","timestamp":1636480543000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/characterization-of-polybacterial-versus-monobacterial-conjunctivitis--peer-reviewed-fulltext-article-OPTH"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":61,"URL":"https:\/\/doi.org\/10.2147\/opth.s335197","relation":{},"ISSN":["1177-5483"],"issn-type":[{"value":"1177-5483","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}