{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T10:42:17Z","timestamp":1775212937761,"version":"3.50.1"},"reference-count":47,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OPTH"],"DOI":"10.2147\/opth.s476419","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T04:15:15Z","timestamp":1726892115000},"page":"2671-2684","source":"Crossref","is-referenced-by-count":3,"title":["A Randomized, Multicenter Phase 3 Clinical Trial Evaluating Intracanalicular Dexamethasone Insert for the Treatment of Allergic Conjunctivitis"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Kenneth","family":"Kenyon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5437-5903","authenticated-orcid":true,"given":"Eugene","family":"McLaurin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8243-2485","authenticated-orcid":true,"given":"Steven","family":"Silverstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Reilly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srilatha","family":"Vantipalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2024,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1097\/ACI.0000000000000204","volume":"15","author":"Leonardi","year":"2015","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"ref2","first-page":"107","volume":"7","author":"Carr","year":"2016","journal-title":"All Rhinol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1097\/ACI.0b013e32834a9676","volume":"11","author":"Rosario","year":"2011","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1016\/j.jaip.2016.10.010","volume":"5","author":"Meltzer","year":"2017","journal-title":"J All Clin Immunol in Practice"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1177\/112067211002000201","volume":"20","author":"Palmares","year":"2010","journal-title":"Europ J Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1111\/j.1398-9995.2007.01583.x","volume":"63","author":"Petersen","year":"2008","journal-title":"Allergy"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"305","DOI":"10.3111\/13696998.2011.576039","volume":"14","author":"Virchow","year":"2011","journal-title":"J Med Econom"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1111\/j.1755-3768.2011.02272.x","volume":"90","author":"Bielory","year":"2012","journal-title":"Acta Ophthalmologica"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.anai.2019.11.014","volume":"124","author":"Bielory","year":"2020","journal-title":"Anna All Asthm Immunol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.ophtha.2018.10.020","volume":"126","author":"Varu","year":"2019","journal-title":"Ophthalmology"},{"key":"ref11","unstructured":"Allergan. FML (Fluorometholone Ophthalmic Suspension, USP) [Prescribing Information]. Madison, NJ: Allergan; 2018."},{"key":"ref12","unstructured":"Bausch + Lomb. LOTEMAX (Loteprednol Etabonate Ophthalmic Suspension) [Prescribing Information]. Bridgewater, NJ: Bausch + Lomb; 2016."},{"key":"ref13","unstructured":"Alcon Laboratories, Inc. MAXIDEX (Dexamethasone Ophthalmic Suspension) [Prescribing Information]. Fort Worth, TX: Alcon Laboratories, Inc; 2017."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1111\/aos.13197","volume":"94","author":"Porela-Tiihonen","year":"2016","journal-title":"Acta Ophthalmologica"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1016\/j.jcrs.2014.02.037","volume":"40","author":"An","year":"2014","journal-title":"J Cataract Refract Surg"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1016\/j.ophtha.2015.03.026","volume":"122","author":"Newman-Casey","year":"2015","journal-title":"Ophthalmology"},{"key":"ref17","unstructured":"American Academy of Ophthalmology. COVID-19 and Your Eye Care. 2020; Available from: https:\/\/www.aao.org\/Assets\/6d7c9a1a-9242-4326-a75d-9c6c9a827594\/637208545943870000\/coronavirus-and-your-eyes-pdf?inline=1. Accessed June 26, 2022."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jtos.2021.04.008","volume":"21","author":"Spencer","year":"2021","journal-title":"Ocul Surf"},{"key":"ref19","unstructured":"Ocular Therapeutix, Inc. DEXTENZA (Dexamethasone Ophthalmic Insert) [Prescribing Information]. Bedford, MA: Ocular Therapeutix, Inc; 2021."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1089\/jop.2016.0025","volume":"32","author":"Blizzard","year":"2016","journal-title":"J Ocul Pharmacol Ther"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.jcrs.2018.09.023","volume":"45","author":"Tyson","year":"2019","journal-title":"J Cataract Refract Surg"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"572","DOI":"10.4172\/2155-9570.1000572","volume":"7","author":"Walters","year":"2016","journal-title":"J Clin Exp Ophthalmol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1001\/archopht.1990.01070030090035","volume":"108","author":"Abelson","year":"1990","journal-title":"Arch Ophthalmol"},{"key":"ref24","first-page":"1495","volume":"8","author":"Bergmann","year":"2014","journal-title":"Clin Ophthalmol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1016\/S0002-9394(03)00708-6","volume":"136","author":"Greiner","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"2617","DOI":"10.2147\/OPTH.S185835","volume":"12","author":"Meier","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1185\/03007995.2010.548797","volume":"27","author":"Torkildsen","year":"2011","journal-title":"Curr Med Res Opin"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1517\/17425255.4.4.453","volume":"4","author":"Abelson","year":"2008","journal-title":"Expert Opin Drug Metab Toxicol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1097\/ICL.0000000000000152","volume":"41","author":"Goldstein","year":"2015","journal-title":"Eye Contact Lens"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1089\/jop.2016.0154","volume":"33","author":"Torkildsen","year":"2017","journal-title":"J Ocul Pharmacol Ther"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/j.ajo.2021.03.017","volume":"229","author":"McLaurin","year":"2021","journal-title":"Am J Ophthalmol"},{"key":"ref32","unstructured":"McLaurin SM, Torkildsen G, Sato M, et al. Evaluating the Safety and Efficacy of DEXTENZA, a Dexamethasone Insert (0.4 mg) for the Treatment of Ocular Itching: results from Three Clinical Trials. Presented at the American Society of Cataract and Refractive Surgery Annual Meeting; May 6, 2019. San Diego, CA; 2019."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1016\/j.jcrs.2015.11.005","volume":"41","author":"Walters","year":"2015","journal-title":"J Cataract Refract Surg"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"67","DOI":"10.5005\/jp-journals-10028-1226","volume":"11","author":"Phulke","year":"2017","journal-title":"J Curr Glauc Pract"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.4103\/ijo.IJO_2143_18","volume":"67","author":"Sen","year":"2019","journal-title":"Indian J Ophthalmol"},{"key":"ref36","first-page":"2131","volume":"7","author":"Rosin","year":"2013","journal-title":"Clin Ophthalmol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1038\/s41433-021-01668-x","volume":"36","author":"Goldstein","year":"2022","journal-title":"Eye"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"707","DOI":"10.2147\/OPTH.S150816","volume":"12","author":"Thygesen","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.ophtha.2018.10.021","volume":"126","author":"Garcia-Ferrer","year":"2019","journal-title":"Ophthalmology"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1016\/j.jfo.2011.12.012","volume":"35","author":"L\u00e9oni-Mespli\u00e9","year":"2012","journal-title":"J Fr Ophtalmol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"461","DOI":"10.4103\/0301-4738.116062","volume":"61","author":"Maharana","year":"2013","journal-title":"Indian J Ophthalmol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1775","DOI":"10.18240\/ijo.2019.11.17","volume":"12","author":"Najmi","year":"2019","journal-title":"Int J Ophthalmol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1111\/j.1365-2222.2012.04025.x","volume":"42","author":"Maspero","year":"2012","journal-title":"Clin Exp Allerg"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.jtos.2021.05.006","volume":"21","author":"Morthen","year":"2021","journal-title":"Ocul Surf"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.anai.2012.01.006","volume":"108","author":"Hom","year":"2012","journal-title":"Ann Allergy Asthma Immunol."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1097\/ACI.0000000000000471","volume":"18","author":"Villani","year":"2018","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"157","DOI":"10.2147\/OPTH.S38732","volume":"7","author":"Gomes","year":"2013","journal-title":"Clin Ophthalmol"}],"container-title":["Clinical Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/95855","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/95855","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T04:15:20Z","timestamp":1726892120000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/a-randomized-multicenter-phase-3-clinical-trial-evaluating-intracanali-peer-reviewed-fulltext-article-OPTH"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":47,"URL":"https:\/\/doi.org\/10.2147\/opth.s476419","relation":{},"ISSN":["1177-5483"],"issn-type":[{"value":"1177-5483","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9]]}}}