{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T01:03:10Z","timestamp":1768525390054,"version":"3.49.0"},"reference-count":31,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OTT"],"DOI":"10.2147\/ott.s264347","type":"journal-article","created":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T22:16:02Z","timestamp":1597184162000},"page":"8049-8054","source":"Crossref","is-referenced-by-count":10,"title":["&lt;p&gt;Metastatic Castration-Resistant Prostate Cancer with Neuroendocrine Transformation and BRCA 1 Germ-Line Mutation: A Case Report and Literature Review&lt;\/p&gt;"],"prefix":"10.2147","volume":"Volume 13","author":[{"given":"Yinhang","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongsheng","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Dou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinbo","family":"Yue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.eururo.2019.08.005","volume":"77","author":"Culp","year":"2020","journal-title":"Eur Urol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1016\/j.cell.2015.05.001","volume":"161","author":"Robinson","year":"2015","journal-title":"Cell"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"4080","DOI":"10.1038\/s41467-018-06177-2","volume":"9","author":"Zhang","year":"2018","journal-title":"Nat Commun"},{"key":"ref4","first-page":"711","volume":"52","author":"Arason","year":"1993","journal-title":"Am J Hum Genet"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3390\/cancers10120487","volume":"10","author":"Faraoni","year":"2018","journal-title":"Cancers"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1016\/S0140-6736(94)91578-4","volume":"343","author":"Ford","year":"1994","journal-title":"Lancet."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1093\/jnci\/94.18.1358","volume":"94","author":"Thompson","year":"2002","journal-title":"J Natl Cancer Inst"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1086\/302525","volume":"65","author":"Hubert","year":"1999","journal-title":"Am J Hum Genet"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1803","DOI":"10.1002\/1097-0142(19870515)59:10<1803::AID-CNCR2820591019>3.0.CO;2-X","volume":"59","author":"Tetu","year":"1987","journal-title":"Cancer."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"2492","DOI":"10.1200\/JCO.2017.77.6880","volume":"36","author":"Aggarwal","year":"2018","journal-title":"J Clin Oncol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.1016\/S0022-5347(17)32417-5","volume":"152","author":"Di Sant\u2019Agnese","year":"1994","journal-title":"J Urol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1046\/j.1464-410X.2003.03066.x","volume":"91","author":"Sciarra","year":"2003","journal-title":"BJU Int"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1002\/pros.10260","volume":"56","author":"Yashi","year":"2003","journal-title":"Prostate"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/bju.13493","volume":"119","author":"Heck","year":"2017","journal-title":"BJU Int"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.2134","author":"Silvestri","year":"2020","journal-title":"JAMA Oncol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1748","DOI":"10.1200\/JCO.2012.43.1882","volume":"31","author":"Castro","year":"2013","journal-title":"J Clin Oncol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.1007\/s12094-019-02274-w","volume":"22","author":"Valero","year":"2020","journal-title":"Clin Transl Oncol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.eururo.2018.01.035","volume":"74","author":"Antonarakis","year":"2018","journal-title":"Eur Urol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1053\/j.seminoncol.2006.10.026","volume":"34","author":"Palmgren","year":"2007","journal-title":"Semin Oncol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/nrm1963","volume":"7","author":"Schreiber","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/nrc2342","volume":"8","author":"Helleday","year":"2008","journal-title":"Nat Rev Cancer"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1200\/JCO.2014.56.2728","volume":"33","author":"Kaufman","year":"2015","journal-title":"J Clin Oncol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1056\/NEJMoa1506859","volume":"373","author":"Mateo","year":"2015","journal-title":"N Engl J Med"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"2091","DOI":"10.1056\/NEJMoa1911440","volume":"382","author":"de Bono","year":"2020","journal-title":"N Engl J Med"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1038\/nature06548","volume":"451","author":"Edwards","year":"2008","journal-title":"Nature"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1038\/nature06633","volume":"451","author":"Sakai","year":"2008","journal-title":"Nature"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1200\/JCO.2016.70.4627","volume":"35","author":"Christie","year":"2017","journal-title":"J Clin Oncol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.1016\/S0140-6736(18)32486-3","volume":"392","author":"Parker","year":"2018","journal-title":"Lancet"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/S0022-5347(17)37427-X","volume":"147","author":"Amato","year":"1992","journal-title":"J Urol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1111\/pin.12860","volume":"69","author":"Kosaka","year":"2019","journal-title":"Pathol Int"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"3072","DOI":"10.1200\/JCO.2002.12.065","volume":"20","author":"Papandreou","year":"2002","journal-title":"J Clin Oncol"}],"container-title":["OncoTargets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=60555","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=60555","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T22:16:05Z","timestamp":1597184165000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/metastatic-castration-resistant-prostate-cancer-with-neuroendocrine-tr-peer-reviewed-article-OTT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":31,"URL":"https:\/\/doi.org\/10.2147\/ott.s264347","relation":{},"ISSN":["1178-6930"],"issn-type":[{"value":"1178-6930","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}