{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:28:50Z","timestamp":1778876930002,"version":"3.51.4"},"reference-count":23,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["OTT"],"DOI":"10.2147\/ott.s265725","type":"journal-article","created":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T20:44:59Z","timestamp":1605559499000},"page":"11849-11853","source":"Crossref","is-referenced-by-count":3,"title":["<p>The Role of Dynamic ctDNA Monitoring During Combination Therapies of BRAF V600E-Mutated Metastatic Colorectal Cancer: A Case Report<\/p>"],"prefix":"10.2147","volume":"Volume 13","author":[{"given":"Zhan","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9364-693X","authenticated-orcid":true,"given":"Chen-Yang","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Li","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miao-Miao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Ping","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-Sheng","family":"Zang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,11]]},"reference":[{"key":"ref1","first-page":"33","volume":"7","author":"T\u00e1rraga L\u00f3pez","year":"2014","journal-title":"Clin Med Insights Gastroenterol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1038\/bjc.2011.19","volume":"104","author":"Yokota","year":"2011","journal-title":"Br J Cancer"},{"key":"ref3","first-page":"2195","volume":"15","author":"Morikawa","year":"2018","journal-title":"Oncol Lett"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2162","DOI":"10.1002\/jcp.25952","volume":"233","author":"Bahrami","year":"2018","journal-title":"J Cell Physiol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.canlet.2017.06.030","volume":"404","author":"Calapre","year":"2017","journal-title":"Cancer Lett"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nrc.2017.7","volume":"17","author":"Wan","year":"2017","journal-title":"Nat Rev Cancer"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1373\/clinchem.2014.222679","volume":"61","author":"Heitzer","year":"2015","journal-title":"Clin Chem"},{"key":"ref8","first-page":"1","volume":"1","author":"Stephen","year":"2017","journal-title":"JCO Precis Oncol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"8760","DOI":"10.1038\/ncomms9760","volume":"6","author":"Murtaza","year":"2015","journal-title":"Nat Commun"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"42008","DOI":"10.18632\/oncotarget.5788","volume":"6","author":"Gray","year":"2015","journal-title":"Oncotarget"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1373\/clinchem.2014.230235","volume":"61","author":"Sanmamed","year":"2015","journal-title":"Clin Chem"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1158\/2159-8290.CD-15-1336","volume":"6","author":"Girotti","year":"2016","journal-title":"Cancer Discov"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1097\/CMR.0000000000000187","volume":"25","author":"Gonzalez-Cao","year":"2015","journal-title":"Melanoma Res"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/s12967-016-0852-6","volume":"14","author":"Schreuer","year":"2016","journal-title":"J Transl Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1093\/annonc\/mdx026","volume":"28","author":"Lee","year":"2017","journal-title":"Ann Oncol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"224ra24","DOI":"10.1126\/scitranslmed.3007094","volume":"6","author":"Bettegowda","year":"2014","journal-title":"Sci Transl Med"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"346ra92","DOI":"10.1126\/scitranslmed.aaf6219","volume":"8","author":"Tie","year":"2016","journal-title":"Sci Transl Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.ctrv.2017.08.006","volume":"60","author":"Strickler","year":"2017","journal-title":"Cancer Treat Rev"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1200\/JCO.18.02459","volume":"37","author":"Van Cutsem","year":"2019","journal-title":"J Clin Oncol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1158\/2159-8290.CD-16-0050","volume":"6","author":"Hong","year":"2016","journal-title":"Cancer Discov"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"4032","DOI":"10.1200\/JCO.2015.63.2497","volume":"33","author":"Kopetz","year":"2015","journal-title":"J Clin Oncol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"443","DOI":"10.2147\/OTT.S180845","volume":"12","author":"Wang","year":"2019","journal-title":"Onco Targets Ther"},{"key":"ref23","first-page":"2522","author":"Fukuoka","year":"2019"}],"container-title":["OncoTargets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=63839","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=63839","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T20:45:01Z","timestamp":1605559501000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/the-role-of-dynamic-ctdna-monitoring-during-combination-therapies-of-b-peer-reviewed-article-OTT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":23,"URL":"https:\/\/doi.org\/10.2147\/ott.s265725","relation":{},"ISSN":["1178-6930"],"issn-type":[{"value":"1178-6930","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11]]}}}