{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T06:08:04Z","timestamp":1779862084372,"version":"3.53.1"},"reference-count":136,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PTT"],"DOI":"10.2147\/ptt.s604199","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T05:50:13Z","timestamp":1779861013000},"page":"1-18","source":"Crossref","is-referenced-by-count":0,"title":["Immunosenescence in Older Patients with Psoriasis: Mechanistic Insights and Opportunities for Biologic Therapy"],"prefix":"10.2147","volume":"Volume 16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9797-7495","authenticated-orcid":true,"given":"Wenjie","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuying","family":"Zha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2437","DOI":"10.3390\/healthcare13192437","volume":"13","author":"Li","year":"2025","journal-title":"Healthcare"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/bjd.19169","volume":"184","author":"Iskandar","year":"2021","journal-title":"Br J Dermatol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"400","DOI":"10.2340\/00015555-3130","volume":"99","author":"Pezzolo","year":"2019","journal-title":"Acta Derm Venereol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000541590","volume":"241","author":"Drewitz","year":"2025","journal-title":"Dermatology"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1038\/s41392-023-01451-2","volume":"8","author":"Liu","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"111218","DOI":"10.1016\/j.humimm.2024.111218","volume":"86","author":"Liu","year":"2025","journal-title":"Hum Immunol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1177\/1203475419897578","volume":"24","author":"Sandhu","year":"2020","journal-title":"J Cutan Med Surg"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1007\/s40266-022-00961-y","volume":"39","author":"Ter Haar","year":"2022","journal-title":"Drugs Aging"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"16095","DOI":"10.3390\/ijms242216095","volume":"24","author":"Man","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1286344","DOI":"10.3389\/fimmu.2023.1286344","volume":"14","author":"Kamata","year":"2023","journal-title":"Front Immunol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1007\/s12016-024-08991-7","volume":"66","author":"Sieminska","year":"2024","journal-title":"Clin Rev Allergy Immunol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"e71119","DOI":"10.1002\/hsr2.71119","volume":"8","author":"Falahi","year":"2025","journal-title":"Health Sci Rep"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1708280","DOI":"10.3389\/fimmu.2025.1708280","volume":"16","author":"M\u00fcller","year":"2025","journal-title":"Front Immunol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"7123","DOI":"10.1111\/febs.15770","volume":"288","author":"Zhang","year":"2021","journal-title":"FEBS J"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1016\/j.exger.2013.09.003","volume":"48","author":"Schmitt","year":"2013","journal-title":"Exp Gerontol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"eabn7774","DOI":"10.1126\/sciadv.abn7774","volume":"8","author":"Chi","year":"2022","journal-title":"Sci Adv"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1038\/nature09447","volume":"467","author":"Ghoreschi","year":"2010","journal-title":"Nature"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.jdermsci.2015.11.007","volume":"81","author":"Yang","year":"2016","journal-title":"J Dermatol Sci"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"13139","DOI":"10.1073\/pnas.1409155111","volume":"111","author":"Qi","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.exger.2017.05.015","volume":"96","author":"Yoshida","year":"2017","journal-title":"Exp Gerontol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.smim.2012.04.006","volume":"24","author":"Berent-Maoz","year":"2012","journal-title":"Semin Immunol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2737","DOI":"10.1111\/all.15272","volume":"77","author":"Roesner","year":"2022","journal-title":"Allergy"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.clim.2019.07.003","volume":"207","author":"Yanes","year":"2019","journal-title":"Clin Immunol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"911050","DOI":"10.3389\/fimmu.2022.911050","volume":"13","author":"Chen","year":"2022","journal-title":"Front Immunol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"3010","DOI":"10.1097\/CM9.0000000000003410","volume":"137","author":"Chen","year":"2024","journal-title":"Chin Med J"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1038\/s12276-025-01527-9","volume":"57","author":"Nguyen","year":"2025","journal-title":"Exp Mol Med"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.3390\/biology14101371","volume":"14","author":"Yuan","year":"2025","journal-title":"Biology"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"4255","DOI":"10.1038\/s41467-022-31935-8","volume":"13","author":"Yong","year":"2022","journal-title":"Nat Commun"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"e13032","DOI":"10.1111\/acel.13032","volume":"18","author":"Cui","year":"2019","journal-title":"Aging Cell"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1530\/REP-19-0330","volume":"159","author":"Zhang","year":"2020","journal-title":"Reproduction"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"65","DOI":"10.5483\/BMBRep.2020.53.2.291","volume":"53","author":"Lee","year":"2020","journal-title":"BMB Rep"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"696605","DOI":"10.3389\/fimmu.2021.696605","volume":"12","author":"Su","year":"2021","journal-title":"Front Immunol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"5002","DOI":"10.3390\/ijms20205002","volume":"20","author":"Tominaga","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"955175","DOI":"10.3389\/fimmu.2022.955175","volume":"13","author":"Xiao","year":"2022","journal-title":"Front Immunol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"7308","DOI":"10.7150\/thno.111352","volume":"15","author":"Barthelaix","year":"2025","journal-title":"Theranostics"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1016\/j.apsb.2024.01.008","volume":"14","author":"Wang","year":"2024","journal-title":"Acta Pharm Sin B"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1222308","DOI":"10.3389\/fimmu.2023.1222308","volume":"14","author":"Moss","year":"2023","journal-title":"Front Immunol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1186\/s12964-025-02308-7","volume":"23","author":"Zhang","year":"2025","journal-title":"Cell Commun Signal"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"1364","DOI":"10.3390\/cells13161364","volume":"13","author":"Lim","year":"2024","journal-title":"Cells"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"e13753","DOI":"10.1111\/acel.13753","volume":"22","author":"Tabibzadeh","year":"2023","journal-title":"Aging Cell"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1111\/exd.14332","volume":"30","author":"Zeng","year":"2021","journal-title":"Exp Dermatol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"896","DOI":"10.3389\/fimmu.2017.00896","volume":"8","author":"Agrawal","year":"2017","journal-title":"Front Immunol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"e13838","DOI":"10.1111\/acel.13838","volume":"22","author":"Bashir","year":"2023","journal-title":"Aging Cell"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1016\/j.immuni.2016.10.010","volume":"45","author":"Durai","year":"2016","journal-title":"Immunity"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"14275","DOI":"10.1038\/ncomms14275","volume":"8","author":"Li","year":"2017","journal-title":"Nat Commun"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1038\/s43587-025-00910-5","volume":"5","author":"Majewska","year":"2025","journal-title":"Nat Aging"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.14336\/AD.2025.10731","volume":"16","author":"Adlimoghaddam","year":"2025","journal-title":"Aging Dis"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"e0273882","DOI":"10.1371\/journal.pone.0273882","volume":"18","author":"Kam","year":"2023","journal-title":"PLoS One"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/nrm3352","volume":"13","author":"Sahin","year":"2012","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"2624","DOI":"10.4049\/jimmunol.1501006","volume":"195","author":"Chougnet","year":"2015","journal-title":"J Immunol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/s41514-024-00144-6","volume":"10","author":"Reitsema","year":"2024","journal-title":"NPJ Aging"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3390\/ijms19010042","volume":"19","author":"Kim","year":"2017","journal-title":"Int J Mol Sci"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-026-09575-1","volume":"9","author":"Gao","year":"2026","journal-title":"Commun Biol"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s12979-025-00540-w","volume":"22","author":"Liu","year":"2025","journal-title":"Immun Ageing"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"622306","DOI":"10.3389\/fimmu.2021.622306","volume":"12","author":"Kucuksezer","year":"2021","journal-title":"Front Immunol"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"S0022\u2013202X(25)03684","DOI":"10.1016\/j.jid.2025.12.015","author":"Braun","year":"2025","journal-title":"J Invest Dermatol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1656398","DOI":"10.3389\/fimmu.2025.1656398","volume":"16","author":"Chen","year":"2025","journal-title":"Front Immunol"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"e70042","DOI":"10.1111\/exd.70042","volume":"34","author":"Yong","year":"2025","journal-title":"Exp Dermatol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1002\/path.2200","volume":"212","author":"Watson","year":"2007","journal-title":"J Pathol"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.2353\/ajpath.2009.080973","volume":"175","author":"Kirschner","year":"2009","journal-title":"Am J Pathol"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1038\/nature06116","volume":"449","author":"Lande","year":"2007","journal-title":"Nature"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1002\/eji.201344277","volume":"45","author":"Lande","year":"2015","journal-title":"Eur J Immunol"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"220","DOI":"10.3390\/medicina61020220","volume":"61","author":"Argalia","year":"2025","journal-title":"Medicina"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"e70642","DOI":"10.1111\/jcmm.70642","volume":"29","author":"Di Vincenzo","year":"2025","journal-title":"J Cell Mol Med"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s00424-009-0726-3","volume":"459","author":"Jylh\u00e4v\u00e4","year":"2010","journal-title":"Pflugers Arch"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1016\/j.jamda.2013.05.009","volume":"14","author":"Michaud","year":"2013","journal-title":"J Am Med Dir Assoc"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"e8392","DOI":"10.1590\/1414-431X20198392","volume":"52","author":"Milan-Mattos","year":"2019","journal-title":"Braz J Med Biol Res"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s11897-025-00710-3","volume":"22","author":"Kurt","year":"2025","journal-title":"Curr Heart Fail Rep"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1093\/gerona\/59.3.m242","volume":"59","author":"Cesari","year":"2004","journal-title":"J Gerontol a Biol Sci Med Sci"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"2392","DOI":"10.1002\/pro.3306","volume":"26","author":"Tran","year":"2017","journal-title":"Protein Sci"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/s41572-025-00630-5","volume":"11","author":"Armstrong","year":"2025","journal-title":"Nat Rev Dis Primers"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/j.det.2010.03.009","volume":"28","author":"Mazza","year":"2010","journal-title":"Dermatol Clin"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"1354593","DOI":"10.3389\/fimmu.2024.1354593","volume":"15","author":"Su","year":"2024","journal-title":"Front Immunol"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"55","DOI":"10.4103\/0378-6323.186498","volume":"83","author":"Ergun","year":"2017","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"ref75","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1093\/rheumatology\/kes305","volume":"52","author":"Listing","year":"2013","journal-title":"Rheumatology"},{"key":"ref76","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1111\/j.1540-9740.2005.04502.x","volume":"4","author":"Behnam","year":"2005","journal-title":"Skinmed"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.5070\/D3271156085","volume":"27","author":"Hong","year":"2021","journal-title":"Dermatol Online J"},{"key":"ref78","first-page":"S115","volume":"33","author":"Johnsson","year":"2015","journal-title":"Clin Exp Rheumatol"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"7581","DOI":"10.1038\/s41467-025-62874-9","volume":"16","author":"Sun","year":"2025","journal-title":"Nat Commun"},{"key":"ref80","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.4049\/jimmunol.1800013","volume":"201","author":"Hawkes","year":"2018","journal-title":"J Immunol"},{"key":"ref81","doi-asserted-by":"publisher","first-page":"e12946","DOI":"10.1111\/sji.12946","volume":"92","author":"Ten Bergen","year":"2020","journal-title":"Scand J Immunol"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1111\/1346-8138.12653","volume":"41","author":"Hayashi","year":"2014","journal-title":"J Dermatol"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"e13224","DOI":"10.1111\/dth.13224","volume":"33","author":"Acer","year":"2020","journal-title":"Dermatol Ther"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"58","DOI":"10.5114\/reum.2021.102618","volume":"59","author":"Gediz","year":"2021","journal-title":"Reumatologia"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"17093","DOI":"10.1007\/s00432-023-05387-6","volume":"149","author":"Jung","year":"2023","journal-title":"J Cancer Res Clin Oncol"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1001\/jamadermatol.2020.2977","volume":"156","author":"Poizeau","year":"2020","journal-title":"JAMA Dermatol"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1016\/j.jaad.2024.12.025","volume":"92","author":"Chen","year":"2025","journal-title":"J Am Acad Dermatol"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"2321194","DOI":"10.1080\/09546634.2024.2321194","volume":"35","author":"Cho","year":"2024","journal-title":"J Dermatolog Treat"},{"key":"ref89","doi-asserted-by":"publisher","first-page":"100991","DOI":"10.1016\/j.ajpc.2025.100991","volume":"22","author":"Chaaban","year":"2025","journal-title":"Am J Prev Cardiol"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"1395968","DOI":"10.3389\/fimmu.2024.1395968","volume":"15","author":"Strunz","year":"2024","journal-title":"Front Immunol"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"101422","DOI":"10.1016\/j.arr.2021.101422","volume":"71","author":"Santoro","year":"2021","journal-title":"Ageing Res Rev"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1111\/1440-1681.13816","volume":"50","author":"Lin","year":"2023","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"103500","DOI":"10.1016\/j.jaut.2025.103500","volume":"157","author":"Zabotti","year":"2025","journal-title":"J Autoimmun"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1016\/S0140-6736(08)60726-6","volume":"371","author":"Papp","year":"2008","journal-title":"Lancet"},{"key":"ref95","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1080\/14712598.2022.2132143","volume":"22","author":"Vu","year":"2022","journal-title":"Expert Opin Biol Ther"},{"key":"ref96","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1159\/000524199","volume":"238","author":"Naik","year":"2022","journal-title":"Dermatology"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/s13555-025-01607-8","volume":"16","author":"Izu-Belloso","year":"2026","journal-title":"Dermatol Ther"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"2583227","DOI":"10.1080\/09546634.2025.2583227","volume":"36","author":"Fenkel","year":"2025","journal-title":"J Dermatolog Treat"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1111\/ddg.15251","volume":"22","author":"Mastorino","year":"2024","journal-title":"J Dtsch Dermatol Ges"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"111897","DOI":"10.1016\/j.celrep.2022.111897","volume":"41","author":"Veras","year":"2022","journal-title":"Cell Rep"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"599947","DOI":"10.3389\/fimmu.2020.599947","volume":"11","author":"Christmann","year":"2020","journal-title":"Front Immunol"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"3080","DOI":"10.1080\/09546634.2022.2114288","volume":"33","author":"Norden","year":"2022","journal-title":"J Dermatolog Treat"},{"key":"ref103","doi-asserted-by":"publisher","first-page":"e15772","DOI":"10.1111\/dth.15772","volume":"35","author":"Tichy","year":"2022","journal-title":"Dermatol Ther"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"e0307050","DOI":"10.1371\/journal.pone.0307050","volume":"19","author":"Dilokthornsakul","year":"2024","journal-title":"PLoS One"},{"key":"ref105","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1111\/jdv.20739","volume":"39","author":"Motedayen Aval","year":"2025","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"2905","DOI":"10.3390\/jcm11102905","volume":"11","author":"Greigert","year":"2022","journal-title":"J Clin Med"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1038\/ajg.2016.298","volume":"111","author":"Targan","year":"2016","journal-title":"Am J Gastroenterol"},{"key":"ref108","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1080\/1744666X.2023.2195165","volume":"19","author":"Burden","year":"2023","journal-title":"Expert Rev Clin Immunol"},{"key":"ref109","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s40257-021-00655-y","volume":"23","author":"Marrakchi","year":"2022","journal-title":"Am J Clin Dermatol"},{"key":"ref110","doi-asserted-by":"publisher","first-page":"321","DOI":"10.20344\/amp.22672","volume":"38","author":"Torres","year":"2025","journal-title":"Acta Med Port"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"1292941","DOI":"10.3389\/fimmu.2023.1292941","volume":"14","author":"Hawkes","year":"2023","journal-title":"Front Immunol"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"9048","DOI":"10.3390\/ijms22169048","volume":"22","author":"Samotij","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1111\/exd.14765","volume":"32","author":"Kodali","year":"2023","journal-title":"Exp Dermatol"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1177\/24755303211051724","volume":"7","author":"Baniel","year":"2022","journal-title":"J Psoriasis Psoriatic Arthritis"},{"key":"ref115","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1177\/10600280241252688","volume":"59","author":"Pathak","year":"2025","journal-title":"Ann Pharmacother"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1007\/s00105-023-05140-7","volume":"74","author":"M\u00fcller","year":"2023","journal-title":"Dermatologie"},{"key":"ref117","doi-asserted-by":"publisher","first-page":"23","DOI":"10.2147\/PTT.S393978","volume":"14","author":"Rega","year":"2024","journal-title":"Psoriasis"},{"key":"ref118","first-page":"1","volume":"29","author":"Bukhari","year":"2024","journal-title":"Skin Therapy Lett"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.jid.2016.08.034","volume":"137","author":"D\u00e1vila-Seijo","year":"2017","journal-title":"J Invest Dermatol"},{"key":"ref120","doi-asserted-by":"publisher","first-page":"2482867","DOI":"10.1080\/09546634.2025.2482867","volume":"36","author":"Yin","year":"2025","journal-title":"J Dermatolog Treat"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"e141193","DOI":"10.1172\/jci.insight.141193","volume":"7","author":"Merleev","year":"2022","journal-title":"JCI Insight"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"645","DOI":"10.5114\/ada.2022.118919","volume":"39","author":"Fr\u0105tczak","year":"2022","journal-title":"Postepy Dermatol Alergol"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"e15157","DOI":"10.1111\/exd.15157","volume":"33","author":"Zang","year":"2024","journal-title":"Exp Dermatol"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1001\/jamadermatol.2022.6051","volume":"159","author":"Zhao","year":"2023","journal-title":"JAMA Dermatol"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"1396036","DOI":"10.3389\/fmed.2024.1396036","volume":"11","author":"Liu","year":"2024","journal-title":"Front Med"},{"key":"ref126","doi-asserted-by":"publisher","first-page":"5770","DOI":"10.3390\/ijms22115770","volume":"22","author":"Ji","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref127","doi-asserted-by":"publisher","first-page":"1873","DOI":"10.3390\/life13091873","volume":"13","author":"Fr\u0105tczak","year":"2023","journal-title":"Life"},{"key":"ref128","doi-asserted-by":"publisher","first-page":"179","DOI":"10.2147\/PTT.S492205","volume":"14","author":"Mao","year":"2024","journal-title":"Psoriasis"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"e04232","DOI":"10.1002\/adhm.202504232","volume":"15","author":"Zhou","year":"2025","journal-title":"Adv Healthc Mater"},{"key":"ref130","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.1016\/j.ccell.2024.09.015","volume":"42","author":"Liu","year":"2024","journal-title":"Cancer Cell"},{"key":"ref131","doi-asserted-by":"publisher","first-page":"eady8566","DOI":"10.1126\/sciadv.ady8566","volume":"11","author":"Wrublewsky","year":"2025","journal-title":"Sci Adv"},{"key":"ref132","doi-asserted-by":"publisher","first-page":"1591197","DOI":"10.3389\/fimmu.2025.1591197","volume":"16","author":"Bogdanova","year":"2025","journal-title":"Front Immunol"},{"key":"ref133","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1089\/jir.2023.0172","volume":"44","author":"Hu","year":"2024","journal-title":"J Interferon Cytokine Res"},{"key":"ref134","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/s00005-018-0527-5","volume":"67","author":"Wawrzycki","year":"2019","journal-title":"Arch Immunol Ther Exp"},{"key":"ref135","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1111\/j.1365-2249.2007.03511.x","volume":"150","author":"Boniface","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"ref136","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1007\/s11596-007-0533-z","volume":"27","author":"Liu","year":"2007","journal-title":"J Huazhong Univ Sci Technolog Med Sci"}],"container-title":["Psoriasis: Targets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/115695","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/115695","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T05:50:15Z","timestamp":1779861015000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/immunosenescence-in-older-patients-with-psoriasis-mechanistic-insights-peer-reviewed-fulltext-article-PTT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":136,"URL":"https:\/\/doi.org\/10.2147\/ptt.s604199","relation":{},"ISSN":["2230-326X"],"issn-type":[{"value":"2230-326X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]}}}