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Accessed January 8, 2023."},{"key":"ref110","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1056\/NEJMoa2119115","volume":"386","author":"Smith","year":"2022","journal-title":"N Engl J Med"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1002\/cncr.10656","volume":"95","author":"Fowler","year":"2002","journal-title":"Cancer"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1200\/JCO.2017.75.4853","volume":"36","author":"Ost","year":"2018","journal-title":"J Clin Oncol"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1001\/jamaoncol.2020.0147","volume":"6","author":"Phillips","year":"2020","journal-title":"JAMA Oncol"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"3377","DOI":"10.1200\/JCO.22.00644","volume":"40","author":"Deek","year":"2022","journal-title":"J Clin Oncol"}],"container-title":["Research and Reports in Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=86895","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=86895","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T16:15:15Z","timestamp":1674058515000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/how-to-improve-the-quality-of-life-of-patients-with-prostate-cancer-tr-peer-reviewed-fulltext-article-RRU"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":114,"URL":"https:\/\/doi.org\/10.2147\/rru.s350793","relation":{},"ISSN":["2253-2447"],"issn-type":[{"value":"2253-2447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]}}}