{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:10:51Z","timestamp":1747206651099,"version":"3.40.5"},"reference-count":22,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RRU"],"DOI":"10.2147\/rru.s485238","type":"journal-article","created":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T04:55:10Z","timestamp":1728449710000},"page":"245-252","source":"Crossref","is-referenced-by-count":1,"title":["Relugolix Plus Enzalutamide For Metastatic Hormone-Sensitive Prostate Cancer: A Case Report"],"prefix":"10.2147","volume":"Volume 16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6666-1088","authenticated-orcid":true,"given":"Alastair","family":"Thomson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucinda","family":"Gunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Victor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellis","family":"Adamson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kashyap","family":"Thakrar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2024,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.ajur.2018.09.001","volume":"6","author":"Etheridge","year":"2019","journal-title":"Asian J Urol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1038\/s41585-022-00669-z","volume":"20","author":"Chen","year":"2023","journal-title":"Nat Rev Urol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1056\/NEJMoa2004325","volume":"382","author":"Shore","year":"2020","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1007\/s11523-022-00944-4","volume":"18","author":"Shirley","year":"2023","journal-title":"Target Oncol"},{"key":"ref5","unstructured":"Accord Healthcare. Orgovyx 120 mg film-coated tablets. Summary of Product Characteristics. Available from https:\/\/products.mhra.gov.uk\/. Accessed May 2024."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1093\/oncolo\/oyad036","volume":"28","author":"Kasparian","year":"2023","journal-title":"Oncologist"},{"key":"ref7","unstructured":"ClinicalTrials.gov. Relugolix + Enzalutamide Study in High-Risk Prostate Cancer. Available from https:\/\/clinicaltrials.gov\/study\/NCT06130995. Accessed June 2024."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.clgc.2023.03.009","volume":"21","author":"George","year":"2023","journal-title":"Clin Genitourin Cancer"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1056\/NEJMoa1503747","volume":"373","author":"Sweeney","year":"2015","journal-title":"New Eng J Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19020972","volume":"19","author":"Andersen","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.euros.2024.03.003","volume":"63","author":"Cornford","year":"2024","journal-title":"Eur Urol Open Sci"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1016\/j.ctrv.2012.12.014","volume":"39","author":"Verbrugghe","year":"2013","journal-title":"Cancer Treat Rev"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1586\/14737140.2016.1159515","volume":"16","author":"Huang","year":"2016","journal-title":"Expert Rev Anticancer Ther"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"4266","DOI":"10.3390\/ijerph18084266","volume":"18","author":"Talens","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1097\/JU.0000000000003081","volume":"209","author":"Higano","year":"2023","journal-title":"J Urol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012419.pub2","volume":"5","author":"Cross","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"e212","DOI":"10.3747\/co.21.1657","volume":"21","author":"Chen","year":"2014","journal-title":"Curr Oncol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1086\/523576","volume":"45","author":"Nagappan","year":"2007","journal-title":"Clinic Infect Dis"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s10928-023-09867-7","volume":"50","author":"Otsuka","year":"2023","journal-title":"J Pharmacokinet Pharmacodyn"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"3372","DOI":"10.1128\/aac.02931-15","volume":"60","author":"Lempers","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s11523-023-00967-5","volume":"18","author":"De La Cerda","year":"2023","journal-title":"Target Oncol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1210\/js.2018-00039","volume":"2","author":"Gagliano-Juc\u00e1","year":"2018","journal-title":"J Endocr Soc"}],"container-title":["Research and Reports in Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/96266","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/96266","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T04:55:14Z","timestamp":1728449714000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/relugolix-plus-enzalutamide-for-metastatic-hormone-sensitive-prostate--peer-reviewed-fulltext-article-RRU"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":22,"URL":"https:\/\/doi.org\/10.2147\/rru.s485238","relation":{},"ISSN":["2253-2447"],"issn-type":[{"type":"electronic","value":"2253-2447"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}