{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T16:24:20Z","timestamp":1783441460149,"version":"3.54.6"},"reference-count":62,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VHRM"],"DOI":"10.2147\/vhrm.s330766","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T01:29:32Z","timestamp":1635902972000},"page":"689-699","source":"Crossref","is-referenced-by-count":10,"title":["Association between Paraoxonase-1 p.Q192R Polymorphism and Coronary Artery Disease susceptibility in the Colombian Population"],"prefix":"10.2147","volume":"Volume 17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0676-1770","authenticated-orcid":true,"given":"David","family":"Corredor-Orlandelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Sambracos-Parrado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Mantilla-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josu\u00e9","family":"Tovar-Tirado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Vega-Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago David","family":"Mendoza-Ay\u00fas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Catalina","family":"Pe\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Fernanda","family":"Leal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Rodr\u00edguez-Carrillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jnr","given":"Juanita","family":"Le\u00f3n-Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0084-3449","authenticated-orcid":true,"given":"Juan Mauricio","family":"Pardo-Oviedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Parra Abaunza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora Constanza","family":"Contreras Bravo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8076-0346","authenticated-orcid":true,"given":"Oscar","family":"Ortega-Recalde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7323-6570","authenticated-orcid":true,"given":"Dora Janeth","family":"Fonseca Mendoza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,11]]},"reference":[{"key":"ref1","unstructured":"World Health Organization. Global Health Estimates: life expectancy and leading causes of death and disability. Global Health Estimates: life expectancy and leading causes of death and disability. 2019. Accessed June 9, 2021. https:\/\/www.who.int\/data\/gho\/data\/themes\/mortality-and-global-health-estimates."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1161\/CIR.0000000000000950","volume":"143","author":"Virani","year":"2021","journal-title":"Circulation"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1093\/eurheartj\/ehs411","volume":"34","author":"Falk","year":"2013","journal-title":"Eur Heart J"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/j.ijcard.2017.05.059","volume":"243","author":"Ponte-Negretti","year":"2017","journal-title":"Int J Cardiol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1146\/annurev.genom.5.061903.175930","volume":"5","author":"Lusis","year":"2004","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2878","DOI":"10.1161\/CIRCULATIONAHA.107.183679","volume":"115","author":"Arnett","year":"2007","journal-title":"Circulation"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.gene.2015.04.088","volume":"567","author":"Mackness","year":"2015","journal-title":"Gene"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"17527","DOI":"10.1074\/jbc.M910376199","volume":"275","author":"Shih","year":"2000","journal-title":"J Biol Chem"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1161\/01.cir.0000023623.87083.4f","volume":"106","author":"Tward","year":"2002","journal-title":"Circulation"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.ymgme.2011.09.018","volume":"105","author":"Zhao","year":"2012","journal-title":"Mol Genet Metab"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.arteri.2016.07.005","volume":"29","author":"Mart\u00ednez-Quintana","year":"2017","journal-title":"Clin Investig Arterioscler"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1038\/ejcn.2014.105","volume":"68","author":"Liu","year":"2014","journal-title":"Eur J Clin Nutr"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/s0021-9150(99)00340-8","volume":"149","author":"Imai","year":"2000","journal-title":"Atherosclerosis"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"e17805","DOI":"10.1371\/journal.pone.0017805","volume":"6","author":"Gupta","year":"2011","journal-title":"PLoS One"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s11010-013-1665-z","volume":"380","author":"Hassan","year":"2013","journal-title":"Mol Cell Biochem"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"e0133719","DOI":"10.1371\/journal.pone.0133719","volume":"10","author":"Bounafaa","year":"2015","journal-title":"PLoS One"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/j.annepidem.2011.08.007","volume":"21","author":"Luu","year":"2011","journal-title":"Ann Epidemiol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.arcmed.2019.02.002","volume":"49","author":"Moreno-God\u00ednez","year":"2018","journal-title":"Arch Med Res"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1590\/2359-3997000000184","volume":"60","author":"de Souza-nogueira","year":"2016","journal-title":"Arch Endocrinol Metab"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/s0021-9150(99)00489-x","volume":"152","author":"Gardemann","year":"2000","journal-title":"Atherosclerosis"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1161\/01.atv.18.10.1611","volume":"18","author":"Ombres","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1172\/JCI118869","volume":"98","author":"Antikainen","year":"1996","journal-title":"J Clin Invest"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/nm.2281","volume":"17","author":"Bouman","year":"2011","journal-title":"Nat Med"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.jacc.2016.03.599","volume":"68","author":"Rodriguez","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"3470145","DOI":"10.1155\/2019\/3470145","volume":"2019","author":"Peng","year":"2019","journal-title":"Cardiovasc Ther"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.jacc.2004.09.067","volume":"45","author":"Serebruany","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1001\/jama.2009.1232","volume":"302","author":"Shuldiner","year":"2009","journal-title":"JAMA"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1097\/MJT.0b013e3181bdc3e4","volume":"17","author":"Sugunaraj","year":"2010","journal-title":"Am J Ther"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"400","DOI":"10.3390\/jpm11050400","volume":"11","author":"Angulo-Aguado","year":"2021","journal-title":"Journal of Personalized Medicine"},{"key":"ref30","first-page":"45","volume":"20","author":"Senior","year":"2013","journal-title":"Revista Colombiana De Cardiologia"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1038\/s41586-020-2308-7","volume":"581","author":"Karczewski","year":"2020","journal-title":"Nature"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1093\/bioinformatics\/btm025","volume":"23","author":"Gonz\u00e1lez","year":"2007","journal-title":"Bioinformatics"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1016\/j.jacc.2009.05.061","volume":"54","author":"Regieli","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"ref34","first-page":"101","volume":"81","author":"Marija","year":"2008","journal-title":"Croatica Chemica Acta"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1353\/hub.2003.0049","volume":"75","author":"Scacchi","year":"2003","journal-title":"Hum Biol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s13410-013-0146-y","volume":"33","author":"Helaly","year":"2013","journal-title":"Int J Diabetes Dev Ctries"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"22","DOI":"10.24265\/horizmed.2017.v17n2.04","volume":"17","author":"Carranza Alva","year":"2017","journal-title":"HorizMed"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.acmx.2016.08.001","volume":"86","author":"Fridman","year":"2016","journal-title":"Arch Cardiol Mex"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1161\/01.ATV.20.9.2120","volume":"20","author":"Sen-Banerjee","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"01","DOI":"10.4172\/2153-0645.1000113","volume":"04","author":"Orengo-Mercado","year":"2013","journal-title":"J Pharmacogenom Pharmacoproteomics"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"6913106","DOI":"10.1155\/2017\/6913106","volume":"2017","author":"Siller-L\u00f3pez","year":"2017","journal-title":"J Toxicol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/978-3-319-09665-0_5","volume":"224","author":"Karlsson","year":"2015","journal-title":"Handb Exp Pharmacol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1038\/28406","volume":"394","author":"Shih","year":"1998","journal-title":"Nature"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"e5298","DOI":"10.1097\/MD.0000000000005298","volume":"95","author":"Hern\u00e1ndez-D\u00edaz","year":"2016","journal-title":"Medicine"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1001\/jama.299.11.1265","volume":"299","author":"Bhattacharyya","year":"2008","journal-title":"JAMA"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0009-9120(02)00295-3","volume":"35","author":"Ferr\u00e9","year":"2002","journal-title":"Clin Biochem"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"51","DOI":"10.4103\/0971-6866.132756","volume":"20","author":"Hampe","year":"2014","journal-title":"Indian J Hum Genet"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"376","DOI":"10.5551\/jat.11320","volume":"19","author":"Bayrak","year":"2012","journal-title":"JAT"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"219","DOI":"10.2174\/1875692117666181227112119","volume":"16","author":"Munshi","year":"2019","journal-title":"CPPM"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1146\/annurev.med.54.101601.152421","volume":"54","author":"Costa","year":"2003","journal-title":"Annu Rev Med"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1038\/clpt.2011.194","volume":"90","author":"Lewis","year":"2011","journal-title":"Clin Pharmacol Ther"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1161\/CIRCINTERVENTIONS.111.963025","volume":"4","author":"Hulot","year":"2011","journal-title":"Circ Cardiovasc Interv"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1038\/nm.2386","volume":"17","author":"Camps","year":"2011","journal-title":"Nat Med"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4172\/2329-6607.1000148","volume":"4","author":"Garcia","year":"2015","journal-title":"Cardiovasc Pharmacol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1080\/10937400903158409","volume":"12","author":"Ginsberg","year":"2009","journal-title":"J Toxicol Environ Health B Crit Rev"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1590\/s1415-47572014000200003","volume":"37","author":"Salzano","year":"2014","journal-title":"Genet Mol Biol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.gde.2016.09.003","volume":"41","author":"Adhikari","year":"2016","journal-title":"Curr Opin Genet Dev"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"e34695","DOI":"10.1371\/journal.pone.0034695","volume":"7","author":"Avena","year":"2012","journal-title":"PLoS One"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1111\/j.1365-2362.2007.01769.x","volume":"37","author":"Roest","year":"2007","journal-title":"Eur J Clin Invest"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"e1007591","DOI":"10.1371\/journal.pgen.1007591","volume":"14","author":"Hendricks","year":"2018","journal-title":"PLoS Genet"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/gepi.22370","volume":"45","author":"Li","year":"2021","journal-title":"Genet Epidemiol"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1111\/cge.13066","volume":"93","author":"Ghouse","year":"2018","journal-title":"Clin Genet"}],"container-title":["Vascular Health and Risk Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=75517","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=75517","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T01:29:43Z","timestamp":1635902983000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/association-between-paraoxonase-1-pq192r-polymorphism-and-coronary-art-peer-reviewed-fulltext-article-VHRM"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":62,"URL":"https:\/\/doi.org\/10.2147\/vhrm.s330766","relation":{},"ISSN":["1178-2048"],"issn-type":[{"value":"1178-2048","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}