{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T09:12:22Z","timestamp":1778231542495,"version":"3.51.4"},"reference-count":20,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VHRM"],"DOI":"10.2147\/vhrm.s601750","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:55:14Z","timestamp":1778230514000},"page":"1-14","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal Associations Between Metabolic Risk Burden and the Cardio\u2013Ankle Vascular Index (CAVI) in Japan Using Health-Check Cohort"],"prefix":"10.2147","volume":"Volume 22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7463-1067","authenticated-orcid":true,"given":"Yuzo","family":"Horibuchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larbi","family":"Aluariachy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9286-752X","authenticated-orcid":true,"given":"Reiko","family":"Yamaura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideko","family":"Kasahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichiro","family":"Tsugane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2026,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"101","DOI":"10.5551\/jat.13.101","volume":"13","author":"Shirai","year":"2006","journal-title":"J Atheroscler Thromb"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2147\/VHRM.S223330","volume":"16","author":"Takahashi","year":"2020","journal-title":"Vasc Health Risk Manag"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1093\/eurheartj\/ehl254","volume":"27","author":"Laurent","year":"2006","journal-title":"Eur Heart J"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e020103","DOI":"10.1161\/JAHA.120.020103","volume":"10","author":"Miyoshi","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/jch.13425","volume":"21","author":"Matsushita","year":"2018","journal-title":"J Clin Hypertens"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1093\/ajh\/hpab178","volume":"35","author":"Budoff","year":"2021","journal-title":"Am J Hypertens"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1186\/s12933-016-0465-7","volume":"15","author":"Gomez-Sanchez","year":"2016","journal-title":"Cardiovasc Diabetol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.5551\/jat.63371","volume":"29","author":"Kim","year":"2022","journal-title":"J Atheroscler Thromb"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e0186863","DOI":"10.1371\/journal.pone.0186863","volume":"12","author":"Yue","year":"2017","journal-title":"PLoS One"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"596","DOI":"10.5551\/jat.31385","volume":"23","author":"Sato","year":"2016","journal-title":"J Atheroscler Thromb"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"629","DOI":"10.5551\/jat.7922","volume":"18","author":"Matsuzawa","year":"2011","journal-title":"J Atheroscler Thromb"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/S0140-6736(05)67402-8","volume":"366","author":"Alberti","year":"2005","journal-title":"Lancet"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1161\/CIRCULATIONAHA.105.169404","volume":"112","author":"Grundy","year":"2005","journal-title":"Circulation"},{"key":"ref14","unstructured":"Ministry of Education, Culture, Sports, Science and Technology; Ministry of Health, Labour and Welfare; Ministry of Economy, Trade and Industry. Ethical Guidelines for Medical and Biological Research Involving Human Subjects. Tokyo, Japan; 2021. https:\/\/www.mext.go.jp\/content\/20250325-mxt_life-000035486-01.pdf?utm_source=chatgpt.com."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"653","DOI":"10.2147\/VHRM.S386077","volume":"19","author":"Nagayama","year":"2023","journal-title":"Vasc Health Risk Manag"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"105107","DOI":"10.1016\/j.ebiom.2024.105107","volume":"103","author":"B\u00e4ck","year":"2024","journal-title":"EBioMedicine"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1161\/HYPERTENSIONAHA.118.11800","volume":"73","author":"Kario","year":"2019","journal-title":"Hypertension"},{"key":"ref18","first-page":"44","volume":"31","author":"Horibuchi","year":"2026","journal-title":"J Int Univ Health Welfare"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2602","DOI":"10.2174\/0929867324666170710121145","volume":"24","author":"Santilli","year":"2017","journal-title":"Curr Med Chem"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-022-01665-8","volume":"21","author":"Ramezankhani","year":"2022","journal-title":"Cardiovasc Diabetol"}],"container-title":["Vascular Health and Risk Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/114960","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/114960","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:55:18Z","timestamp":1778230518000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/longitudinal-associations-between-metabolic-risk-burden-and-the-cardio-peer-reviewed-fulltext-article-VHRM"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":20,"URL":"https:\/\/doi.org\/10.2147\/vhrm.s601750","relation":{},"ISSN":["1178-2048"],"issn-type":[{"value":"1178-2048","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]}}}