{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T00:05:12Z","timestamp":1648857912636},"reference-count":42,"publisher":"University of Tokushima Faculty of Medicine","issue":"1.2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Invest."],"published-print":{"date-parts":[[2020]]},"DOI":"10.2152\/jmi.67.182","type":"journal-article","created":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T22:06:42Z","timestamp":1588370802000},"page":"182-188","source":"Crossref","is-referenced-by-count":0,"title":["Past infections are associated with low levels of anti-citrullinated protein autoantibodies in rheumatoid arthritis"],"prefix":"10.2152","volume":"67","author":[{"given":"Kenji","family":"Tani","sequence":"first","affiliation":[{"name":"General Medicine and Primary Care, Tokushima University Hospital, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minaho","family":"Kanamori","sequence":"additional","affiliation":[{"name":"Student Lab, The University of Tokushima Faculty of Medicine, Tokushima, Japan"},{"name":"Department of General Medicine, Institute of Biomedical Sciences, The University of Tokushima Graduate School, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaro","family":"Nagase","sequence":"additional","affiliation":[{"name":"Student Lab, The University of Tokushima Faculty of Medicine, Tokushima, Japan"},{"name":"Department of General Medicine, Institute of Biomedical Sciences, The University of Tokushima Graduate School, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Okura","sequence":"additional","affiliation":[{"name":"General Medicine and Primary Care, Tokushima University Hospital, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Kawaminami","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Institute of Biomedical Sciences, The University of Tokushima Graduate School, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Kawahito","sequence":"additional","affiliation":[{"name":"Kaifu Tokushima Prefectural Hospital, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Inaba","sequence":"additional","affiliation":[{"name":"Yoshinogawa Medical Center, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Inaba","sequence":"additional","affiliation":[{"name":"Yoshinogawa Medical Center, Tokushima, Japan"},{"name":"Tokushima Prefectural Central Hospital, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Miyatake","sequence":"additional","affiliation":[{"name":"Yamakami Hospital, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Institute of Biomedical Sciences, The University of Tokushima Graduate School, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Tabata","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Institute of Biomedical Sciences, The University of Tokushima Graduate School, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Institute of Biomedical Sciences, The University of Tokushima Graduate School, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harutaka","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Institute of Biomedical Sciences, The University of Tokushima Graduate School, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"925","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Shimizu T, Tani K, Hase K, Ogawa H, Huang L, Shinomiya F, Sone S. CD13\u2006\/\u2006aminopeptidase N\u2013induced lymphocyte involvement in inflamed joints of rheumatoid arthritis. Arthritis Rheum. 46\u2005:\u20052330-8, 2002","DOI":"10.1002\/art.10517"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Tani K, Shimizu T, Motoki Y, Sone S. Chemokines in synovial inflammation in rheumatoid arthritis\u2005:\u2005basic and clinical aspects. Mod Rheumatol 12(2)\u2005:\u200593-9, 2002","DOI":"10.3109\/s101650200017"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Paul BJ, Kandy HI, Krishnan V. Pre-rheumatoid arthritis and its prevention. Eur J Rheumatol 4(2)\u2005:\u2005161-5, 2017","DOI":"10.5152\/eurjrheum.2017.16006"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Zamanpoor M. The genetic pathogenesis, diagnosis and therapeutic insight of rheumatoid arthritis. Clin Genet 95(5)\u2005:\u2005547-57, 2019","DOI":"10.1111\/cge.13498"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Liao KP, Alfredsson L, Karlson EW. Environmental influences on risk for rheumatoid arthritis. Curr Opin Rheumatol 21(3)\u2005:\u2005279-83, 2009","DOI":"10.1097\/BOR.0b013e32832a2e16"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Honda K, Littman DR. The microbiota in adaptive immune homeostasis and disease. Nature 7-535(7610)\u2005:\u200575-84, 2016","DOI":"10.1038\/nature18848"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Yuasa S, Yamaguchi H , Nakanishi Y , Kawaminami S, Tabata R, Shimizu N, Kohno M, Shimizu T, Miyata J, Nakayama M, Kishi J, Toyoda Y, Nishioka Y, Tani K. Treatment responses and their predictors in patients with rheumatoid arthritis treated with biological agents. J Med Invest 60\u2005:\u200577-90, 2013","DOI":"10.2152\/jmi.60.77"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. van der Linden MP, Knevel R, Huizinga TW, van der Helm-van Mil AH. Classification of rheumatoid arthritis\u2005:\u2005comparison of the 1987 American College of Rheumatology criteria and the 2010 American College of Rheumatology\u2006\/\u2006European League Against Rheumatism criteria. Arthritis Rheum 63(1)\u2005:\u200537-42, 2011","DOI":"10.1002\/art.30100"},{"key":"9","unstructured":"9. de Brito Rocha S, Baldo DC, Andrade LEC. Clinical and pathophysiologic relevance of autoantibodies in rheumatoid arthritis. Ann Rheum Dis 70(1)\u2005:\u2005128-33, 2011"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. van de Stadt LA, van der Horst AR, de Koning MH, Bos WH, Wolbink GJ, van de Stadt RJ, Pruijn GJ, Dijkmans BA, van Schaardenburg D, Hamann D. The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia. Ann Rheum Dis 70(1)\u2005:\u2005128-33, 2011","DOI":"10.1136\/ard.2010.132662"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Willemze A, B\u00f6hringer S, Knevel R, Levarht EW, Stoeken-Rijsbergen G, Houwing-Duistermaat JJ, van der Helm-van Mil AH, Huizinga TW, Toes RE, Trouw LA. The ACPA recognition profile and subgrouping of ACPA-positive RA patients. Ann Rheum Dis 71(2)\u2005:\u2005268-74, 2012","DOI":"10.1136\/annrheumdis-2011-200421"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medsger TA, Mitchell DM, Neustadt DH, Pinals RS, Schaller JG, Sharp JT, Wilder RL, Hunder GG. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31(3)\u2005:\u2005315-24, 1988","DOI":"10.1002\/art.1780310302"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Heydari-Kamjani M, Demory Beckler M, Kesselman MM. Reconsidering the Use of Minocycline in the Preliminary Treatment Regime of Rheumatoid Arthritis. Cureus. 11(8)\u2005:\u2005 e5351, 2019.","DOI":"10.7759\/cureus.5351"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Darrah E, Andrade F. Rheumatoid arthritis and citrullination. Curr Opin Rheumatol 30(1)\u2005:\u200572-78, 2018","DOI":"10.1097\/BOR.0000000000000452"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Pedersen M, Jacobsen S, Klarlund M, Pedersen BV, Wiik A, Wohlfahrt J, Frisch M. Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides. Arthritis Res Ther 8(4)\u2005:\u2005R133, 2006","DOI":"10.1186\/ar2022"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Klareskog L, Widhe M, Hermansson M, R\u00f6nnelid J. Antibodies to citrullinated proteins in arthritis\u2005:\u2005pathology and promise. Curr Opin Rheumatol 20(3)\u2005:\u2005300-5, 2008","DOI":"10.1097\/BOR.0b013e3282fbd22a"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. De Rycke L, Nicholas AP, Cantaert T, Kruithof E, Echols JD, Vandekerckhove B, Veys EM, De Keyser F, Baeten D. Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity. Arthritis Rheum 52(8)\u2005:\u20052323-30, 2005","DOI":"10.1002\/art.21220"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Fisher BA, Venables PJ. Inhibiting citrullination in rheumatoid arthritis\u2005:\u2005taking fuel from the fire. Arthritis Res Ther 14(1)\u2005:\u2005108-9, 2012","DOI":"10.1186\/ar3740"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Foulquier C, Sebbag M, Clavel C, Chapuy-Regaud S, Al Badine R, M\u00e9chin MC, Vincent C, Nachat R, Yamada M, Takahara H, Simon M, Guerrin M, Serre G. Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation. Arthritis Rheum 56(11)\u2005:\u20053541-53, 2007","DOI":"10.1002\/art.22983"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Engstr\u00f6m M, Eriksson K, Lee L, Hermansson M, Johansson A, Nicholas AP, Gerasimcik N, Lundberg K, Klareskog L, Catrina AI, Yucel-Lindberg T. Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis. J Transl Med 16(1)\u2005:\u2005214-27, 2018","DOI":"10.1186\/s12967-018-1588-2"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Valesini G, Gerardi MC, Iannuccelli C, Pacucci VA, Pendolino M, Shoenfeld Y. Citrullination and autoimmunity. Autoimmun Rev 14(6)\u2005:\u2005490-7, 2015","DOI":"10.1016\/j.autrev.2015.01.013"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Diaz-Gallo LM, Ramsk\u00f6ld D, Shchetynsky K, Folkersen L, Chemin K, Brynedal B, Uebe S, Okada Y, Alfredsson L, Klareskog L, Padyukov L. Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis. Ann Rheum Dis 77(10)\u2005:\u20051454-62, 2018","DOI":"10.1136\/annrheumdis-2018-213412"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Ronninger M, Seddighzadeh M, Eike MC, Plant D, Daha NA, Skinningsrud B, Worthington J, Kvien TK, Toes RE, Lie BA, Alfredsson L, Padyukov L. Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis. PLoS One 7(3)\u2005:\u2005e32861, 2012","DOI":"10.1371\/journal.pone.0032861"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Elliott SE, Kongpachith S, Lingampalli N, Adamska JZ, Cannon BJ, Mao R, Blum LK, Robinson WH. Affinity maturation drives epitope spreading and generation of proinflammatory anti-citrullinated protein antibodies in rheumatoid arthritis. Arthritis Rheumatol 70(12)\u2005:\u20051946-58, 2018","DOI":"10.1002\/art.40587"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Deane KD, Demoruelle MK, Kelmenson LB, Kuhn KA, Norris JM, Holers VM. Genetic and environmental risk factors for rheumatoid arthritis. Best Pract Res Clin Rheumatol 31(1)\u2005:\u20053-18, 2017","DOI":"10.1016\/j.berh.2017.08.003"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Kudaeva FM, Speechley MR, Pope JE. A systematic review of viral exposures as a risk for rheumatoid arthritis. Semin Arthritis Rheum 48(4)\u2005:\u2005587-96, 2019","DOI":"10.1016\/j.semarthrit.2018.03.011"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Cannon JW, Abouzeid M, de Klerk N, Dibben C, Carapetis JR, Katzenellenbogen JM. Environmental and social determinants of acute rheumatic fever\u2005:\u2005a longitudinal cohort study. Epidemiol Infect 147\u2005:\u2005e79, 2019","DOI":"10.1017\/S0950268818003527"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Tani K, Murphy WJ, Chertov O, Salcedo R, Koh CY, Utsunomiya I, Funakoshi S, Asai O, Herrmann SH, Wang JM, Kwak LW, Oppenheim JJ. Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens. Int Immunol 12\u2005:\u2005691-700, 2000","DOI":"10.1093\/intimm\/12.5.691"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Tani K, Murphy WJ, Chertov O, Oppenheim JJ, Wang JM. The neutrophil granule protein cathepsin G activates murine T lymphocytes and up-regulates antigen-specific Ig production in mice. Biochem Biophys Res Comun 282\u2005:\u2005971-6, 2001","DOI":"10.1006\/bbrc.2001.4676"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Chertov O, Ueda H, Xu LL, Tani K, Murphy WJ, Wang JM, Howard OM, Sayers TJ, Oppenheim JJ. Identification of human neutrophil-derived cathepsin G and azurocidin\u2006\/\u2006CAP37 as chemoattractants for mononuclear cells and neutrophils. J Exp Med 186(5)\u2005:\u2005739-47, 1997","DOI":"10.1084\/jem.186.5.739"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Stobernack T, du Teil Espina M, Mulder LM, Palma Medina LM, Piebenga DR, Gabarrini G, Zhao X, Janssen KMJ, Hulzebos J, Brouwer E, Sura T, Becher D, van Winkelhoff AJ, G\u00f6tz F, Otto A, Westra J, van Dijl JM. A secreted bacterial peptidylarginine deiminase can neutralize human innate immune defenses. MBio 9(5)\u2005:\u2005e01704-18, 2018","DOI":"10.1128\/mBio.01704-18"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Wright HL, Moots RJ, Edwards SW. The multifactorial role of neutrophils in rheumatoid arthritis. Nat Rev Rheumatol. 10(10)\u2005:\u2005593-601, 2014","DOI":"10.1038\/nrrheum.2014.80"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Apel F, Zychlinsky A, Kenny EF. The role of neutrophil extracellular traps in rheumatic diseases. Nat Rev Rheumatol 14(8)\u2005:\u2005467-75, 2018","DOI":"10.1038\/s41584-018-0039-z"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Wong SL, Wagner DD. Peptidylarginine deiminase 4\u2005:\u2005a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging. FASEB J fj201800691R, 2018","DOI":"10.1096\/fj.201800691R"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. O\u2019Neil LJ, Kaplan MJ. Neutrophils in rheumatoid arthritis\u2005:\u2005Breaking immune tolerance and fueling disease. Trends Mol Med 25(3)\u2005:\u2005215-27, 2019","DOI":"10.1016\/j.molmed.2018.12.008"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Pollmann S, Stensland M, Halvorsen EH, Sollid LM, Kvien TK, Fleckenstein B, Molberg O. Anti-PAD4 autoantibodies in rheumatoid arthritis\u2005:\u2005levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate. Rheumatol Int 32(5)\u2005:\u20051271-6, 2012","DOI":"10.1007\/s00296-010-1765-y"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Auger I, Martin M, Balandraud N, Roudier J. Rheumatoid arthritis-specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen. Arthritis Rheum 62(1)\u2005:\u2005126-31, 2010","DOI":"10.1002\/art.27230"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Sandberg ME, Bengtsson C, Klareskog L, Alfredsson L, Saevarsdottir S. Recent infections are associated with decreased risk of rheumatoid arthritis\u2005:\u2005a population-based case-control study. Ann Rheum Dis 74 (5)\u2005:\u2005904-7, 2015.","DOI":"10.1136\/annrheumdis-2014-206493"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Karlson EW, Chang SC, Cui J, Chibnik LB, Fraser PA, De Vivo I, Costenbader KH. Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis. Ann Rheum Dis 69(1)\u2005:\u200554-60, 2010","DOI":"10.1136\/ard.2008.102962"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Corr\u00eaa MG, Sacchetti SB, Ribeiro FV, Pimentel SP, Casarin RC, Cirano FR, Casati MZ. Periodontitis increases rheumatic factor serum levels and citrullinated proteins in gingival tissues and alter cytokine balance in arthritic rats. PLoS One 12(3)\u2005:\u2005e0174442, 2017","DOI":"10.1371\/journal.pone.0174442"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41. Potempa J, Mydel P, Kozieel J. The case for periodontitis in the pathogenesis of rheumatoid arthritis. Nat Rev Rheumatol 13(10)\u2005:\u2005606-20, 2017","DOI":"10.1038\/nrrheum.2017.132"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42. Malmstr\u00f6m V, Catrina AI, Klareskog L. The immunopathogenesis of seropositive rheumatoid arthritis\u2005:\u2005from triggering to targeting. Nat Rev Immunol 17(1)\u2005:\u200560-75, 2017","DOI":"10.1038\/nri.2016.124"}],"container-title":["The Journal of Medical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jmi\/67\/1.2\/67_182\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,8]],"date-time":"2021-06-08T01:06:16Z","timestamp":1623114376000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jmi\/67\/1.2\/67_182\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":42,"journal-issue":{"issue":"1.2","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.2152\/jmi.67.182","relation":{},"ISSN":["1343-1420","1349-6867"],"issn-type":[{"value":"1343-1420","type":"print"},{"value":"1349-6867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}