{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T13:22:55Z","timestamp":1788009775525,"version":"build-2784847793"},"reference-count":21,"publisher":"University of Tokushima Faculty of Medicine","issue":"3.4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Invest."],"published-print":{"date-parts":[[2021]]},"DOI":"10.2152\/jmi.68.368","type":"journal-article","created":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T22:27:38Z","timestamp":1636583258000},"page":"368-371","source":"Crossref","is-referenced-by-count":4,"title":["A puerperal patient with agranulocytosis during tazobactam\u2009\/\u2009piperacillin administration\u2005:\u2005A case report"],"prefix":"10.2152","volume":"68","author":[{"given":"Haruna","family":"Iwazawa","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takakiyo","family":"Tatsumichi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyo","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Motoki","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Kanenishi","sequence":"additional","affiliation":[{"name":"Department of Perinatology and Gynecology, Kagawa University Graduate School of Medicine, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Kosaka","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Kagawa University Hospital, Ikenobe, Miki, Kagawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"925","reference":[{"key":"1","unstructured":"1. ZOSYN\u00ae Interview form, 18th ed. Taisho Toyama Pharmaceutical &amp; Co., Ltd., Tokyo, 2020"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Perry CM, Markham A\u2005:\u2005Piperacillin\u2009\/\u2009tazobactam\u2005:\u2005an updated review of its use in the treatment of bacterial infections. Drugs 57\u2005:\u2005805-843, 1999","DOI":"10.2165\/00003495-199957050-00017"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Nishida K, Higashitani F, Hyodo A\u2005:\u2005Superior effect of tazobactam\u2009\/\u2009piperacillin compared to piperacillin on beta-lactamase-producing Pseudomonas aeruginosa. Chemotherapy 43\u2005:\u2005171-178, 1997","DOI":"10.1159\/000239554"},{"key":"4","unstructured":"4. The Japanese Association for Infectious Diseases (JAID), Japanese Society of Chemotherapy (JSC)\u2005:\u2005Guidelines for Treatment of Respiratory Infectious Diseases, JAID, JSC. Tokyo\u2005:\u200521-48, 2014"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Andersohn F, Konzen C, Garbe E\u2005:\u2005Systematic review\u2005:\u2005agranulocytosis induced by nonchemotherapy drugs. Ann Intern Med 146\u2005:\u2005657-665, 2007","DOI":"10.7326\/0003-4819-146-9-200705010-00009"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Kaufman DW, Kelly JP, Jurgelon JM, Anderson T, Issaragrisil S, Wiholm BE, Young NS, Leaverton P, Levy M, Shapiro S\u2005:\u2005Drugs in the aetiology of agranulocytosis and aplastic anaemia. Eur J Haematol Suppl 60\u2005:\u200523-30, 1996","DOI":"10.1111\/j.1600-0609.1996.tb01641.x"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Kaufman DW, Kelly JP, Issaragrisil S, Laporte JR, Anderson T, Levy M, Shapiro S, Young NS\u2005:\u2005Relative incidence of agranulocytosis and aplastic anemia. Am J Hematol 8\u2005:\u200565-67, 2006","DOI":"10.1002\/ajh.20489"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Lee KW, Chow KM, Chan NP, Lo AO, Szeto CC\u2005:\u2005Piperacillin\u2009\/\u2009tazobactam Induced myelosuppression. J Clin Med Res 1\u2005:\u200553-55, 2009","DOI":"10.4021\/jocmr2009.03.1227"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Macwilliam JL, Mistry R, Floyd MS Jr, Baird AD\u2005:\u2005Piperacillin\u2009\/\u2009tazobactam induced thrombocytopaenia--a delayed response. BMJ Case Rep 2012","DOI":"10.1136\/bcr.03.2012.5981"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Nguyen VD, Tourigny JF, Roy R, Brouillette D\u2005:\u2005Rapid-onset thrombocytopenia following piperacillin-tazobactam reexposure. Pharmacotherapy 35\u2005:\u2005e326-e330, 2015","DOI":"10.1002\/phar.1675"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Ruiz-Irastorza G, Barreiro G, Aguirre C\u2005:\u2005Reversible bone marrow depression by high-dose piperacillin\u2009\/\u2009tazobactam. Br J Haematol 95\u2005:\u2005611-612, 1996","DOI":"10.1046\/j.1365-2141.1996.d01-1952.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Chen H, Fan Z, Guo F, Yang Y, Li J, Zhang J, Wang Y, LE J, Wang Z, Zhu J\u2005:\u2005Tazobactam and piperacillin-induced thrombocytopenia\u2005:\u2005a case report. Exp Ther Med 11\u2005:\u20051223-1226, 2016","DOI":"10.3892\/etm.2016.3062"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Boxer LA\u2005:\u2005Neutropenia. In\u2005:\u2005Sills RH, eds. Practical Algorithms in Pediatric Hematology and Hematology and Oncology. S. Karger AG, Albany, 2003, 42-43","DOI":"10.1159\/000069595"},{"key":"14","unstructured":"14. Pisciotta AV\u2005:\u2005Immune and toxic mechanisms in drug-induced agranulocytosis. Semin Hematol 10\u2005:\u2005279-310, 1973"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Saxon A, Adelman DC, Patel A, Hajdu R, Calandra GB\u2005:\u2005 Imipenem cross-reactivity with penicillin in humans. J Allergy Clin Immunol 82(2)\u2005:\u2005213-7, 1988","DOI":"10.1016\/0091-6749(88)91001-9"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Atanaskovic-Markovic M, Gaeta F, Medjo B, Viola M, Nestorovic B, Romano A\u2005:\u2005Tolerability of meropenem in children with IgE-mediated hypersensitivity to penicillins. Allergy 63(2)\u2005:\u2005237-40, 2008","DOI":"10.1111\/j.1398-9995.2007.01532.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Reichardt P, Handrick W, Linke A, Schille R, Kiess W\u2005:\u2005Leukocytopenia, thrombocytopenia and fever related to piperacillin\u2009\/\u2009tazobactam treatment--a retrospective analysis in 38 children with cystic fibrosis. Infection 27\u2005:\u2005355-356, 1999","DOI":"10.1007\/s150100050042"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Kaufman DW, Kelly JP, Levy M, Shapiro S\u2005:\u2005Drug etiology of agranulocytosis\u2005:\u2005an update of the international agranulocytosis and aplastic anemia study. Pharmacoepidemiol Drug Saf 2\u2005:\u2005S25-S29, 1993","DOI":"10.1002\/pds.2630020706"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Young NS\u2005:\u2005Agranulocytosis. JAMA 271\u2005:\u2005935-938, 1994","DOI":"10.1001\/jama.271.12.935"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. American Academy of Pediatrics Committee on Drugs\u2005:\u2005Transfer of drugs and other chemicals into human milk. Pediatrics 108\u2005:\u2005776-789, 2001","DOI":"10.1542\/peds.108.3.776"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Sauberan JB, Bradley JS, Blumer J, Stellwagen LM\u2005:\u2005Transmission of meropenem in breast milk. Pediatr Infect Dis J 31\u2005:\u2005832-834, 2012","DOI":"10.1097\/INF.0b013e318256f4bf"}],"container-title":["The Journal of Medical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jmi\/68\/3.4\/68_368\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T04:41:57Z","timestamp":1636778517000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jmi\/68\/3.4\/68_368\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":21,"journal-issue":{"issue":"3.4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2152\/jmi.68.368","relation":{},"ISSN":["1343-1420","1349-6867"],"issn-type":[{"value":"1343-1420","type":"print"},{"value":"1349-6867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}