{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T10:14:58Z","timestamp":1753438498193},"reference-count":25,"publisher":"University of Tokushima Faculty of Medicine","issue":"3.4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Invest."],"published-print":{"date-parts":[[2023]]},"DOI":"10.2152\/jmi.70.361","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T22:14:49Z","timestamp":1699481689000},"page":"361-368","source":"Crossref","is-referenced-by-count":1,"title":["Early Prediction of Radiotherapeutic Efficacy in a Mouse Model of Non-Small Cell Lung Carcinoma Using <sup>18<\/sup>F-FLT and <sup>18<\/sup>F-FDG PET\/CT"],"prefix":"10.2152","volume":"70","author":[{"given":"Tamaki","family":"Otani","sequence":"first","affiliation":[{"name":"Advance Radiation Research, Education, and Management Center, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Ikushima","sequence":"additional","affiliation":[{"name":"Department of Therapeutic Radiology, Institute of Biomedical Science, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshimi","family":"Bando","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Institute of Biomedical Science, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiko","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Analytical Pathology, Institute of Biomedical Science, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenmei","family":"Kuwahara","sequence":"additional","affiliation":[{"name":"Faculty of Health Science, Tokushima University Graduate School of Medicine, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Otsuka","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging\/Nuclear Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuya","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Oncological Medical Services, Institute of Biomedical Science, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Miyoshi","sequence":"additional","affiliation":[{"name":"Advance Radiation Research, Education, and Management Center, Tokushima University, Tokushima, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"925","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Thomas M, Macha HN, Ukena D, Hamm M, Deppermann M, Semik M, Riesenbeck D, R?be C, Heinecke A:Cisplatin\/etoposide (PE) followed by twice-daily chemoradiation (hfRT\/CT) versus PE alone before surgery in stage III non-small cell lung cancer (NSCLC):a randomised phase III trial of the German Lung Cancer Cooperative Group (GLCCG). J Clin Oncol ?22:7004, 2004","DOI":"10.1200\/jco.2004.22.90140.7004"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Faber LP, Kittle CF, Warren WH, Bonomi PD, Taylor 4th SG, Reddy S, Lee MS:Preoperative chemotherapy and irradiation for stage III non-small cell lung cancer. Ann Thorac Surg 47:669-75;discussion 676-7, 1989","DOI":"10.1016\/0003-4975(89)90115-X"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Skarin A, Jochelson M, Sheldon T, Malcolm A, Oliynyk P, Overholt R, Hunt M, Frei 3rd E:Neoadjuvant chemotherapy in marginally resectable stage III M0 non-small cell lung cancer:Long-term follow-up in 41 patients. J Surg Oncol 40:266-74, 1989","DOI":"10.1002\/jso.2930400413"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Okawara G, Mackay JA, Evans WK, Ung YC:Management of unresected stage III non-small cell lung cancer:a systematic review. J Thorac Oncol 1:377-93, 2006","DOI":"10.1016\/S1556-0864(15)31598-7"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Albain KS, Scott CB, Rusch VR, Turrisi AT, Shepherd FA, Smith C, Gandara DR, Johnson DH, Green MR, Miller RC, for RTOG, SWOG, NCIC-CTG, ECOG, CALGB:NCCTG Phase III comparison of concurrent chemotherapy plus radiotherapy (CT\/RT) and CT\/RT followed by surgical resection for stage IIIA (pN2) non-small cell lung cancer:initial results from intergroup trial 0139 (RTOG 93-09). Proc Am Soc Clin Oncol 22:621, 2003","DOI":"10.1016\/S0169-5002(03)91657-6"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Christensen JD, Colby TV, Patz Jr EF:Correlation of [18F]-2-fluoro-deoxy-D-glucose positron emission tomography standard uptake values with the cellular composition of stage I nonsmall cell lung cancer. Cancer 116:4095-102, 2010","DOI":"10.1002\/cncr.25302"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Sauter AW, Spira D, Schulze M, Pfannenberg C, Hetzel J, Reimold M, Klotz E, Claussen CD, Horger MS:Correlation between [18F]FDG PET\/CT and volume perfusion CT in primary tumours and mediastinal lymph nodes of non-small-cell lung cancer. Eur J Nucl Med Mol Imaging 40:677-84, 2013","DOI":"10.1007\/s00259-012-2318-2"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Mac Manus MP, Hicks RJ, Matthews JP, Wirth A, Rischin D, Ball DL:Metabolic (FDG-PET) response after radical radiotherapy\/chemoradiotherapy for non-small cell lung cancer correlates with patterns of failure. Lung Cancer 49:95-108, 2005","DOI":"10.1016\/j.lungcan.2004.11.024"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Hicks RJ, Mac Manus MP, Matthews JP, Hogg A, Binns D, Rischin D, Ball DL, Peters LJ:Early FDG-PET imaging after radical radiotherapy for non-small-cell lung cancer:inflammatory changes in normal tissues correlate with tumour response and do not confound therapeutic response evaluation. Int J Radiat Oncol Biol Phys 60:412-8, 2004","DOI":"10.1016\/j.ijrobp.2004.03.036"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Zheng Y, Yang Z, Zhang Y, Shi Q, Bao X, Zhang J, Yuan H, Yao Z, Hu C, Zhang Y:The preliminary study of 18F-FLT micro-PET\/CT in predicting radiosensitivity of human nasopharyngeal carcinoma xenografts. Ann Nucl Med 29:29-36, 2015","DOI":"10.1007\/s12149-014-0906-x"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Chalkidou A, Landau DB, Odell EW, Cornelius VR, O\u2019Doherty MJ, Marsden PK:Correlation between Ki-67 immunohistochemistry and 18F-fluorothymidine uptake in patients with cancer:a systematic review and meta-analysis. Eur J Cancer 48:3499-513, 2012","DOI":"10.1016\/j.ejca.2012.05.001"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Fujino H, Kondo K, Miyoshi T, Ishikura H, Takahashi Y, Sawada N, Hirose Y, Takizawa H, Nagao T, Sakiyama S, Monden Y:Establishment of patient-like SCID mouse model by orthotopically implanting primary cultured cells from surgically-resected lung cancer tissues. Oncol Rep 10:1709-15, 2003","DOI":"10.3892\/or.10.6.1709"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Otani T, Kondo K, Takizawa H, Kajiura K, Fujino H, Otsuka H, Miyoshi H:Non-invasive monitoring of cisplatin and erlotinib efficacy against lung cancer in orthotopic SCID mouse models by small animal FDG-PET\/CT and CT. Oncol Rep 41:447-54, 2019","DOI":"10.3892\/or.2018.6818"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Kitao T, Hirata K, Shima K, Hayashi T, Sekizawa M, Takei T, Ichimura W, Harada M, Kondo K, Tamaki N:Reproducibility and uptake time dependency of volume-based parameters on FDG-PET for lung cancer. BMC Cancer 16:576, 2016","DOI":"10.1186\/s12885-016-2624-3"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Hoshikawa H, Mori T, Yamamoto Y, Kishino T, Fukumura T, Samukawa Y, Mori N, Nishiyama Y:Prognostic value comparison between 18F-FLT PET\/CT and 18F-FDG PET\/CT volume-based metabolic parameters in patients with head and neck cancer. Clin Nucl Med 40(6):464-8, 2015","DOI":"10.1097\/RLU.0000000000000652"},{"key":"16","unstructured":"16. Lloyd R, Osamura RY, Kloppel G, Rosai J:WHO classification of tumours of endocrine organs. 4th ed. Lyon:IARC Press:2017"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Magota K, Kubo N, Kuge Y, Nishijima K, Zhao S, Tamaki N:Performance characterization of the Inveon preclinical small-animal PET\/SPECT\/CT system for multimodality imaging. Eur J Nucl Med Mol Imaging 38:742-52, 2011","DOI":"10.1007\/s00259-010-1683-y"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Molthoff CF, Klabbers BM, Berkhof J, Felten JT, van Gelder M, Windhorst AD, Slotman BJ, Lammertsma AA:?Monitoring response to radiotherapy in human squamous cell cancer bearing nude mice:comparison of 2\u2019-deoxy-2\u2019-[18F]fluoro-D-glucose (FDG) and 3\uff62-[18F]fluoro-3\uff62-deoxythymidine (FLT). Mol Imaging Biol 9:340-7, 2007","DOI":"10.1007\/s11307-007-0104-5"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Everitt SJ, Ball DL, Hicks RJ, Callahan J, Plumridge N, Collins M, Herschtal A, Binns D, Kron T, Schneider M, MacManus M:Differential 18F-FDG and 18F-FLT uptake on serial PET\/CT imaging before and during definitive chemoradiation for non-small cell lung cancer. J Nucl Med 55(7):1069-74, 2014","DOI":"10.2967\/jnumed.113.131631"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Christensen TN, Langer SW, Persson G, Larsen KR, Loft A, Amtoft AG, Berthelsen AK, Johannesen HH, Keller SH, Kjaer A, Fischer BM:18F-FLT PET\/CT adds value to 18F-FDG PET\/CT for diagnosing relapse after definitive radiotherapy in patients with lung cancer:results of a prospective clinical trial. J Nucl Med 62:628-35, 2021","DOI":"10.2967\/jnumed.120.247742"},{"key":"21","unstructured":"21. Buck AK, Halter G, Schirrmeister H, Kotzerke J, Wurziger I, Glatting G, Mattfeldt T, Neumaier B, Reske SN, Hetzel M:Imaging proliferation in lung tumors with PET:18F-FLT versus 18F-FDG. J Nucl Med 44:1426-31, 2003"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Gerbaudo VH, Killoran JH, Kim CK, Hornick JL, Nowak JA, Enzinger PC, Mamon HJ:Pilot study of serial FLT and FDG-PET\/CT imaging to monitor response to neoadjuvant chemoradiotherapy of esophageal adenocarcinoma:correlation with histopathologic response. Ann Nucl Med 32:165-74, 2018","DOI":"10.1007\/s12149-018-1229-0"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Wang Z, Wang Y, Sui X, Zhang W, Shi R, Zhang Y, Dang Y, Qiao Z, Zhang B, Song W, Jiang J:Performance of FLT-PET for pulmonary lesion diagnosis compared with traditional FDG-PET:a meta-analysis. Eur J Radiol 84:1371-7, 2015","DOI":"10.1016\/j.ejrad.2015.03.025"},{"key":"24","unstructured":"24. Jensen MM, Kjaer A:Monitoring of anti-cancer treatment with 18F-FDG and 18F-FLT PET:a comprehensive review of pre-clinical studies. Am J Nucl Med Mol Imaging 5(5):431-56, 2015"},{"key":"25","doi-asserted-by":"publisher","unstructured":"25. Goerres GW, Schmid DT, Bandhauer F, Huguenin PU, von Schulthess GK, Schmid S, Stoeckli SJ:Positron emission tomography in the early follow-up of advanced head and neck cancer. Arch Otolaryngol Head Neck Surg 130:105-9, 2004. doi:10.1001\/archotol.130.1.105.","DOI":"10.1001\/archotol.130.1.105"}],"container-title":["The Journal of Medical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jmi\/70\/3.4\/70_361\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T05:15:56Z","timestamp":1699679756000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jmi\/70\/3.4\/70_361\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":25,"journal-issue":{"issue":"3.4","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.2152\/jmi.70.361","relation":{},"ISSN":["1343-1420","1349-6867"],"issn-type":[{"value":"1343-1420","type":"print"},{"value":"1349-6867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]}}}