{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T02:10:07Z","timestamp":1748052607980,"version":"3.41.0"},"reference-count":0,"publisher":"Global Cardiology Science and Practice","issue":"2","license":[{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["gcsp"],"abstract":"<jats:p>\n\n\nA 21-year-old female with no prior cardiac history presented multiple times with chest pain and elevated cardiac biomarkers. Single-photon emission computed tomography revealed a reversible perfusion defect, and coronary angiography was attempted, but was aborted. After multiple similar presentations without angiography, the patient suffered ST-elevation myocardial infarction. Coronary angiography revealed 99% subtotal occlusion of the left main coronary artery and a reduced ejection fraction of 20% complicated by cardiac arrest and cardiogenic shock requiring mechanical circulatory support-assisted percutaneous coronary intervention and veno-arterial extracorporeal membrane oxygenation as a bridge to recovery. An extensive workup did not reveal any secondary causes. Despite frequent follow-up and strict adherence to dual antiplatelet therapy, she developed recurrent angina and was found to have severe in-stent restenosis of the left main coronary artery, requiring two-vessel coronary artery bypass grafting. Despite normal blood counts prior to surgery, post-surgical labs revealed blast-phase acute myeloid leukemia, prompting the initiation of chemotherapy.\n\n\n<\/jats:p>","DOI":"10.21542\/gcsp.2025.24","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T01:45:47Z","timestamp":1747878347000},"source":"Crossref","is-referenced-by-count":0,"title":["Recurrent, isolated left main coronary artery stenosis in a young female"],"prefix":"10.21542","volume":"2025","author":[{"family":"Brianna Skaff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff","family":"Spindel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya","family":"Ignaszewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8990","published-online":{"date-parts":[[2025,5,21]]},"container-title":["Global Cardiology Science and Practice"],"original-title":[],"link":[{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/download\/810\/645","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/download\/810\/645","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T01:47:42Z","timestamp":1748051262000},"score":1,"resource":{"primary":{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/view\/810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,21]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,5,21]]}},"URL":"https:\/\/doi.org\/10.21542\/gcsp.2025.24","relation":{},"ISSN":["2305-7823"],"issn-type":[{"type":"electronic","value":"2305-7823"}],"subject":[],"published":{"date-parts":[[2025,5,21]]}}}