{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:44:50Z","timestamp":1761972290561,"version":"build-2065373602"},"reference-count":0,"publisher":"Global Cardiology Science and Practice","issue":"5","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["gcsp"],"abstract":"<jats:p>Introduction: Heart failure is a clinical syndrome characterized by signs and symptoms of structural and\/or functional alterations accompanied by impaired expulsion of blood or ventricular filling. COVID-19 contributes to circulatory failure and frequently induces or facilitates pulmonary artery thrombosis. HF can be a risk factor as well as a complication of COVID-19.\nAims: The purpose of this study was to evaluate the association between HFpEF isolate and RHF + HFpEF on mortality according to sex in hospitalized patients caused by COVID-19.Methods: A prospective cohort study was performed on hospitalized COVID-19 patients from February 2021 to October 2022. Patients \u226518 years with COVID-19 and an echocardiogram during their hospitalization were included. We excluded patients with HIV, shock, and with missing data.\nResults: A total of 105 patients were included in this study. The median age was 64 years (50-76), 32% (n=37) of the subjects were women. Patients with \u201cHFpEF + RHF\u201d were found to have an increased risk of death (HR 5.58; 95% CI 1.26-24.6, p=0.023) compared to those with HFpEF alone. A comparison of all patients with HFpEF vs \u201cHFpEF + RHF\u201d according to sex, revealed that women and men with \u201cHFpEF + RHF\u201d had greater mortality than those with HFpEF alone, (p=0.0129, p=0.081), respectively. \nConclusions: Heart failure is an important condition associated with poor prognosis irrespective of the cause of hospitalization. COVID-19 causes damage to the heart and is associated with \u201cRHF and HFpEF\u201d. Furthermore, there were found an increased incidence of \u201cRHF and HFpEF\u201d in women.<\/jats:p>","DOI":"10.21542\/gcsp.2025.47","type":"journal-article","created":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T03:37:57Z","timestamp":1761968277000},"source":"Crossref","is-referenced-by-count":0,"title":["Heart failure with preserved ejection fraction: the impact of right heart failure on risk mortality in hospitalized COVID-19 patients: Cohort study"],"prefix":"10.21542","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0661-1916","authenticated-orcid":false,"given":"Roc\u00edo N.","family":"S\u00e1nchez Santill\u00e1n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arturo","family":"Orea-Tejeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3378-1769","authenticated-orcid":false,"given":"Dulce","family":"Gonz\u00e1lez-Islas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celemi","family":"Vigil-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luz Magdaly","family":"Jim\u00e9nez-Gallardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Hern\u00e1ndez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benigno","family":"Valderrabano-Salas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro","family":"Monta\u00f1ez Orozco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas","family":"Pe\u00f1a-Espinosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura P","family":"Arcos-Pacheco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8990","published-online":{"date-parts":[[2025,10,31]]},"container-title":["Global Cardiology Science and Practice"],"original-title":[],"link":[{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/download\/916\/678","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/download\/916\/678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T03:37:57Z","timestamp":1761968277000},"score":1,"resource":{"primary":{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/view\/916"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,10,31]]}},"URL":"https:\/\/doi.org\/10.21542\/gcsp.2025.47","relation":{},"ISSN":["2305-7823"],"issn-type":[{"value":"2305-7823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,31]]}}}