{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T05:46:06Z","timestamp":1767246366135,"version":"3.48.0"},"reference-count":0,"publisher":"Global Cardiology Science and Practice","issue":"6","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["gcsp"],"abstract":"<jats:p>Background: Exercise stress testing is the gold standard for evaluating peripheral arterial disease (PAD) and exercise-induced pulmonary hypertension, but traditional treadmill testing has operational limitations including need for patient transport, specialized facilities, and inability to perform invasive hemodynamic monitoring during exercise.\nMethods: This prospective single-center feasibility study enrolled 54 consecutive patients undergoing ABI (n=35) or RHC (n=19) procedures at Owensboro Medical Practice. The Bedside Bike (Bedside Bike, LLC; 510(k)-exempt Class I device, product code ION) was integrated into routine vascular laboratory and catheterization laboratory workflows. Primary endpoints included exercise completion rates, data interpretability, and safety. Prespecified success criteria were: completion rate \u226590% and interpretability \u226580% for ABI; completion rate \u226590% and interpretability \u226570% for RHC; system usability \u226580% for both.\nResults: Exercise was attempted in 94.4% (51\/54; 95% CI: 87.0-100%) of patients with a 94.1% (48\/51; 95% CI: 86.3-100%) completion rate among those who attempted. Data interpretability was excellent: 97.1% (34\/35; 95% CI: 91.4-100%) for ABI and 84.2% (16\/19; 95% CI: 68.4-100%) for RHC. All prespecified feasibility criteria were met. System usability ratings were 85.7% (95% CI: 74.3-97.1%) for ABI and 89.5% (95% CI: 73.7-100%) for RHC. Adverse events were minor and occurred in 14.3% of ABI and 5.3% of RHC procedures. Among RHC patients with paired measurements, median cardiac output increased from 4.0 [IQR: 3.8-4.7] L\/min at rest to 5.0 [4.8-6.5] L\/min with exercise, with a median mPAP\/CO slope of 8.26 [6.88-14.12] mmHg\/L\/min.\nConclusions: This feasibility study demonstrates that bedside exercise testing using a portable pedaling device is technically feasible, safe, and well-tolerated for both ABI and RHC procedures. These preliminary results support larger studies to evaluate diagnostic validity and clinical utility.<\/jats:p>","DOI":"10.21542\/gcsp.2025.63","type":"journal-article","created":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T05:43:17Z","timestamp":1767246197000},"source":"Crossref","is-referenced-by-count":0,"title":["Feasibility of in-bed exercise testing using a clamp-on pedaling device: A single-center pragmatic study"],"prefix":"10.21542","volume":"2025","author":[{"given":"Neil K.","family":"Jairath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Mijares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kishor M.","family":"Vora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8990","published-online":{"date-parts":[[2025,12,31]]},"container-title":["Global Cardiology Science and Practice"],"original-title":[],"link":[{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/download\/952\/700","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/download\/952\/700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T05:43:18Z","timestamp":1767246198000},"score":1,"resource":{"primary":{"URL":"https:\/\/globalcardiologyscienceandpractice.com\/index.php\/gcsp\/article\/view\/952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,31]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,12,31]]}},"URL":"https:\/\/doi.org\/10.21542\/gcsp.2025.63","relation":{},"ISSN":["2305-7823"],"issn-type":[{"value":"2305-7823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,31]]}}}