{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T10:37:53Z","timestamp":1776422273232,"version":"3.51.2"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,1,2]],"date-time":"2013-01-02T00:00:00Z","timestamp":1357084800000},"content-version":"vor","delay-in-days":2243,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Andrology"],"published-print":{"date-parts":[[2006,11,12]]},"abstract":"<jats:p>\n                    <jats:bold>ABSTRACT:<\/jats:bold>\n                    The effectiveness of \u03b1\u2010adrenergic antagonists on patients with chronic prostatitis\/chronic pelvic pain syndrome (CP\/CPPS) has not been supported by well\u2010evaluated study. The meta\u2010analysis was performed to supply the best evidence about use of this class of drugs in CP\/CPPS. A fully recursive literature search to June 2005 was conducted in PubMed, EMBASE, the Cochrane Controlled Trials Register, and the Chinese Biomedicine Database to identify potentially relevant randomized controlled trials. RevMan4.2 was used for statistical analysis. Nine studies with 734 patients were included. Combined analysis showed a significant reduction of total NIH\u2010CPSI or I\u2010PSS in patients with treatment duration of more than 3 months. There were also valuable results in urinary symptom alleviation. Alph\u03b1\u2010adrenergic antagonists did not show benefit in pain. The meta\u2010analysis revealed that the use of \u03b1\u2010adrenergic antagonists was warranted in CP\/CPPS, and the treatment duration should be long enough (more than 3 months).\n                  <\/jats:p>","DOI":"10.2164\/jandrol.106.000661","type":"journal-article","created":{"date-parts":[[2006,11,2]],"date-time":"2006-11-02T13:43:47Z","timestamp":1162475027000},"page":"847-852","source":"Crossref","is-referenced-by-count":25,"title":["The Effect of \u03b1\u2010Adrenergic Antagonists in Chronic Prostatitis\/Chronic Pelvic Pain Syndrome: A Meta\u2010Analysis of Randomized Controlled Trials"],"prefix":"10.1002","volume":"27","author":[{"given":"Gang","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuru","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sixiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-8-200410190-00005"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)63960-2"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)01637-0"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/089277904773582804"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1024487604631"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1017504830834"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(03)00169-X"},{"key":"e_1_2_5_9_1","first-page":"99","article-title":"Classification, epidemiology and implications of chronic prostatitis in North America, Europe and Asia","volume":"56","author":"Krieger JN","year":"2004","journal-title":"Minerva Urol Nefrol"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.3.236"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2004.11.006"},{"key":"e_1_2_5_12_1","first-page":"169","article-title":"[Alph\u03b1\u2010blockers and bioflavonoids in men with chronic nonbacterial prostatitis (NIH\u2010IIIa): a prospective, placebo\u2010controlled trial]","volume":"25","author":"Lu M.","year":"2004","journal-title":"Zhonghua Liuxing Bingxue Zazhi"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030656"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-133-5-200009050-00013"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(03)00466-7"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0266462300009570"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000117811.40279.19"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-200320150-00004"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2003.11.002"},{"key":"e_1_2_5_20_1","first-page":"518","article-title":"[Effect and mechanism of alpha1\u2010adrenoceptor blocker combined with antibiotics for chronic prostatitis]","volume":"10","author":"Shen B.","year":"2004","journal-title":"Zhonghua Nan Ke Xue"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.01.042"},{"key":"e_1_2_5_22_1","first-page":"48","article-title":"[Treatment of external RF hyperthermia combining with alpha 1\u2010adrenergic receptor blocker for patients with prostatodynia and chronic non\u2010bacterial prostatitis]","volume":"8","author":"Wang J.","year":"2002","journal-title":"Zhonghua Nan Ke Xue"}],"container-title":["Journal of Andrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.2164%2Fjandrol.106.000661","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.2164\/jandrol.106.000661","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T08:56:28Z","timestamp":1697100988000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.2164\/jandrol.106.000661"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,12]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,11,12]]}},"alternative-id":["10.2164\/jandrol.106.000661"],"URL":"https:\/\/doi.org\/10.2164\/jandrol.106.000661","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1058930.510858","asserted-by":"object"}]},"ISSN":["0196-3635","1939-4640"],"issn-type":[{"value":"0196-3635","type":"print"},{"value":"1939-4640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,12]]}}}