{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T16:47:41Z","timestamp":1758127661096},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,1,2]],"date-time":"2013-01-02T00:00:00Z","timestamp":1357084800000},"content-version":"vor","delay-in-days":1639,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Andrology"],"published-print":{"date-parts":[[2008,7,8]]},"abstract":"<jats:p><jats:bold>ABSTRACT: <\/jats:bold> The aim of this study was to compare the efficiency of using a double ejaculate with the efficiency of using a single ejaculate for intrauterine insemination in male subfertility. Eligibility for the study was a total motile sperm count between 1 \u00d7 10<jats:sup>6<\/jats:sup> and 5 \u00d7 10<jats:sup>6<\/jats:sup> on postwash sperm analysis. Thirty\u2010nine couples were randomized to the study group, while another 50 couples were randomized to serve as the control group. Males in the study group were asked to produce a second semen sample within 2 hours of the first sample on the day of insemination. In the study group, the mean total motile sperm count in the first sample was 3.83 \u00d7 10<jats:sup>6<\/jats:sup> (SD \u00b1 0.85 \u00d7 10<jats:sup>6<\/jats:sup>; range 1.1\u20134.9) and 3.99 \u00d7 10<jats:sup>6<\/jats:sup> (SD \u00b1 0.72 \u00d7 10<jats:sup>6<\/jats:sup>; range 0.9\u20134.4) in the control group. The mean total motile sperm count in the second sample was 3.52 \u00d7 10<jats:sup>6<\/jats:sup> (SD \u00b1 1.46 \u00d7 10<jats:sup>6<\/jats:sup>; range 0.9\u20133.7) in the study group. The mean total motile sperm count in the final inseminate was 7.35 \u00d7 10<jats:sup>6<\/jats:sup> (SD \u00b1 1.90 \u00d7 10<jats:sup>6<\/jats:sup>; range 2.9\u201310.6) in the study group. The difference in total motile sperm counts between the study and the control group was statistically significant (<jats:italic>P<\/jats:italic> &lt; .001). There were 6 pregnancies in the study group, providing a pregnancy rate of 15.3%, whereas there were 5 pregnancies in the control group, representing a pregnancy rate of 10% (<jats:italic>P<\/jats:italic> = .44). We concluded that although it does not increase the pregnancy rate significantly, obtaining a second semen sample when the motile sperm yield of the first semen sample is 1 million to 5 million significantly increases the total motile sperm count in the final inseminate.<\/jats:p>","DOI":"10.2164\/jandrol.107.004754","type":"journal-article","created":{"date-parts":[[2008,6,4]],"date-time":"2008-06-04T21:55:47Z","timestamp":1212616547000},"page":"404-407","source":"Crossref","is-referenced-by-count":5,"title":["Intrauterine Insemination With Double Ejaculate Compared With Single Ejaculate in Male Factor Infertility: A Pilot Study"],"prefix":"10.1002","volume":"29","author":[{"given":"Tansu","family":"K\u00fc\u00e7\u00fck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eran","family":"Sozen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burcu","family":"Buluc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)81377-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)90722-6"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a019244"},{"key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S0015-0282(16)48870-9","article-title":"Improved semen quality after a short interval second ejaculation","volume":"44","author":"Check JH","year":"1985","journal-title":"Fertil Steril"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.6.1553"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00519-6"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)54168-5"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/8.4.373"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)57784-X"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)04002-7"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02068871"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)55799-9"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)01773-9"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.7.1458"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.3.630"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh390"},{"key":"e_1_2_5_18_1","volume-title":"WHO Laboratory Manual for the Examination of Human Semen and Semen\u2010Cervical Mucus Interaction","author":"Organization World Health","year":"1999"}],"container-title":["Journal of Andrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.2164%2Fjandrol.107.004754","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.2164\/jandrol.107.004754","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T21:03:48Z","timestamp":1697144628000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.2164\/jandrol.107.004754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,8]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,7,8]]}},"alternative-id":["10.2164\/jandrol.107.004754"],"URL":"https:\/\/doi.org\/10.2164\/jandrol.107.004754","archive":["Portico"],"relation":{},"ISSN":["0196-3635","1939-4640"],"issn-type":[{"value":"0196-3635","type":"print"},{"value":"1939-4640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,8]]}}}