{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T02:46:01Z","timestamp":1775529961705,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,1,2]],"date-time":"2013-01-02T00:00:00Z","timestamp":1357084800000},"content-version":"vor","delay-in-days":114,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Andrology"],"published-print":{"date-parts":[[2012,9,10]]},"abstract":"<jats:p><jats:bold>Abstract:<\/jats:bold> Chronic prostatitis\/chronic pelvic pain syndrome (CP\/CPPS) is a common condition that adversely affects men across a wide range of ages. A number of pharmacologic and nonpharmacologic therapies for CP\/CPPS have been investigated. Our study aimed to evaluate the prevalence of CPPS in Korean men in their thirties and to investigate the effect of CPPS and medical treatment on semen quality. Of 314 men with prostatitis, 74 patients with CPPS class IIIA (23.6%) were eligible for the study; these patients underwent combined \u03b1\u2010blocker and cyclo\u2010oxygenase 2 inhibitor therapy. These 74 men were prospectively studied at a medical center in Seoul, Korea. A number of parameters, including ejaculations per month, semen variables, and the levels of hormones (such as follicle\u2010stimulating hormone, estradiol [E<jats:sub>2<\/jats:sub>], luteinizing hormone [LH], testosterone, and prolactin) were evaluated. The mean number of ejaculations per month, the mean number of daily hours spent sitting at work, smoking, body mass index, LH and E<jats:sub>2<\/jats:sub> levels, and semen parameters all showed significant differences (<jats:italic>P<\/jats:italic> &lt; .0001) between the study patients and the controls. The combined regimen was effective in improving all aspects of semen quality except morphology (<jats:italic>P<\/jats:italic> &lt; .05). CPPS class IIIA, which is notably prevalent among Korean men in the fourth decade of life, affects semen quality and poses a challenge to fertility. Proper treatment of CPPS class IIIA results in improved semen quality. Men with CPPS therefore require proper evaluation and treatment by andrologists\/urologists before planning a natural conception.<\/jats:p>","DOI":"10.2164\/jandrol.111.014555","type":"journal-article","created":{"date-parts":[[2012,9,19]],"date-time":"2012-09-19T14:13:14Z","timestamp":1348063994000},"page":"876-885","source":"Crossref","is-referenced-by-count":13,"title":["Chronic Pelvic Pain Syndrome and Semen Quality of Korean Men in Their Fourth Decade"],"prefix":"10.1002","volume":"33","author":[{"given":"Jae Sang","family":"Byun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Ki","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong Woo","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin 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