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This is a very important clinical problem because patients with dyslipidemia are at increased risk of developing erectile dysfunction (ED); hence, statins exert a protective effect. At the same time, the administration of these drugs reduce endothelial dysfunction, a key etiopathogenetic factor in the onset of ED. Moreover, statins are universally considered a key element of secondary prevention for vascular events; therefore, several points are opened. In this critical summary, we attempt to evaluate the effects of statins on ED and to understand the mechanisms through which statins improve the quality of erection and the possible synergism with V phosphodiesterase inhibitors, drugs largely used for the treatment of ED.<\/jats:p>","DOI":"10.2164\/jandrol.111.015230","type":"journal-article","created":{"date-parts":[[2012,7,13]],"date-time":"2012-07-13T09:40:55Z","timestamp":1342172455000},"page":"552-558","source":"Crossref","is-referenced-by-count":19,"title":["Statins and Erectile Dysfunction: A Critical Summary of Current Evidence"],"prefix":"10.1002","volume":"33","author":[{"given":"Sandro","family":"La Vignera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosita 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