{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T18:11:52Z","timestamp":1698775912744},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drugs in R & D"],"published-print":{"date-parts":[[2008]]},"DOI":"10.2165\/0126839-200809060-00006","type":"journal-article","created":{"date-parts":[[2008,11,10]],"date-time":"2008-11-10T08:10:01Z","timestamp":1226304601000},"page":"435-446","source":"Crossref","is-referenced-by-count":3,"title":["Pharmacokinetic-Pharmacodynamic Interaction between Nebicapone, a Novel Catechol-O-Methyltransferase Inhibitor, and Controlled-Release Levodopa\/Carbidopa 200\u00a0mg\/50\u00a0mg"],"prefix":"10.1007","volume":"9","author":[{"given":"Manuel","family":"Vaz-da-Silva","sequence":"first","affiliation":[]},{"given":"Ana I","family":"Loureiro","sequence":"additional","affiliation":[]},{"given":"Teresa","family":"Nunes","sequence":"additional","affiliation":[]},{"given":"Carlos","family":"Lopes","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9","family":"Rocha","sequence":"additional","affiliation":[]},{"given":"Rita","family":"Machado","sequence":"additional","affiliation":[]},{"given":"Raquel","family":"Costa","sequence":"additional","affiliation":[]},{"given":"Leonel","family":"Torr\u00e3o","sequence":"additional","affiliation":[]},{"given":"Am\u00edlcar","family":"Falc\u00e3o","sequence":"additional","affiliation":[]},{"given":"Lyndon","family":"Wright","sequence":"additional","affiliation":[]},{"given":"Luis","family":"Almeida","sequence":"additional","affiliation":[]},{"given":"Patr\u00edcio","family":"Soares-da-Silva","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"R1-6-20081110","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1517\/14728214.11.3.403","volume":"11","author":"Morgan","year":"2006","journal-title":"Expert Opin Emerg Drugs"},{"key":"R2-6-20081110","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1586\/14737175.6.1.91","volume":"6","author":"Rajput","year":"2006","journal-title":"Expert Rev Neurother"},{"key":"R3-6-20081110","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1212\/WNL.34.8.991","volume":"34","author":"Rajput","year":"1984","journal-title":"Neurology"},{"key":"R4-6-20081110","first-page":"985","volume":"II","author":"Quinn","year":"1984","journal-title":"Lancet"},{"key":"R5-6-20081110","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1212\/WNL.62.1_suppl_1.S31","volume":"62","author":"Poewe","year":"2004","journal-title":"Neurology"},{"key":"R6-6-20081110","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1212\/WNL.55.1.24","volume":"55","author":"Dingemanse","year":"2000","journal-title":"Neurology"},{"key":"R8-6-20081110","first-page":"S45","volume":"17","author":"Lang","year":"2002","journal-title":"Mov Disord"},{"key":"R9-6-20081110","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/S0140-6736(05)61511-5","volume":"352","author":"Assal","year":"1998","journal-title":"Lancet"},{"key":"R10-6-20081110","first-page":"263","volume":"2","author":"Benabou","year":"2003","journal-title":"Expert Opin Drug Saf"},{"key":"R11-6-20081110","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1212\/WNL.62.1_suppl_1.S39","volume":"62","author":"Brooks","year":"2004","journal-title":"Neurology"},{"key":"R12-6-20081110","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0014-2999(02)02879-0","volume":"460","author":"Bonifacio","year":"2003","journal-title":"Eur J Pharmacol"},{"key":"R13-6-20081110","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0014-2999(01)01020-2","volume":"420","author":"Parada","year":"2001","journal-title":"Eur J Pharmacol"},{"key":"R14-6-20081110","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00002826-200401000-00007","volume":"27","author":"Almeida","year":"2004","journal-title":"Clin Neuropharmacol"},{"key":"R15-6-20081110","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1159\/000068730","volume":"68","author":"Parada","year":"2003","journal-title":"Pharmacology"},{"key":"R16-6-20081110","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s00228-003-0680-5","volume":"59","author":"Silveira","year":"2003","journal-title":"Eur J Clin Pharmacol"},{"key":"R17-6-20081110","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2165\/00126839-200304040-00001","volume":"4","author":"Almeida","year":"2003","journal-title":"Drugs R D"},{"key":"R18-6-20081110","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1177\/0091270003258666","volume":"43","author":"Almeida","year":"2003","journal-title":"J Clin Pharmacol"},{"key":"R19-6-20081110","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1124\/dmd.106.010447","volume":"34","author":"Loureiro","year":"2006","journal-title":"Drug Metab Dispos"},{"key":"R20-6-20081110","first-page":"S641","volume":"21","author":"Almeida","year":"2006","journal-title":"Mov Disord"},{"key":"R21-6-20081110","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/wnf.0b013e3180645cb0","volume":"31","author":"Ferreira","year":"2008","journal-title":"Clin Neuropharmacol"},{"key":"R22-6-20081110","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1476-5381.1996.tb15220.x","volume":"117","author":"Vieira-Coelho","year":"1996","journal-title":"Br J Pharmacol"},{"key":"R23-6-20081110","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0006-8993(99)01063-X","volume":"821","author":"Vieira-Coelho","year":"1999","journal-title":"Brain Res"},{"key":"R24-6-20081110","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/01.wnf.0000166393.33781.87","volume":"28","author":"Paija","year":"2005","journal-title":"Clin Neuropharmacol"},{"key":"R25-6-20081110","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/00002826-199502000-00006","volume":"18","author":"Ahtila","year":"1995","journal-title":"Clin Neuropharmacol"},{"key":"R26-6-20081110","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s004150050209","volume":"245","author":"Jorga","year":"1998","journal-title":"J Neurol"}],"container-title":["Drugs in R & D"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T12:59:20Z","timestamp":1550235560000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.2165\/0126839-200809060-00006"}},"subtitle":["Randomized, Double-Blind, Placebo-Controlled, Crossover\u00a0Study in Healthy Subjects"],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":25,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.2165\/0126839-200809060-00006","relation":{},"ISSN":["1174-5886"],"issn-type":[{"value":"1174-5886","type":"print"}],"subject":[],"published":{"date-parts":[[2008]]}}}