{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T17:37:19Z","timestamp":1771695439480,"version":"3.50.1"},"reference-count":40,"publisher":"IWA Publishing","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012056","name":"Enhancing Learning and Research for Humanitarian Assistance","doi-asserted-by":"publisher","award":["Research on Health in Humanitarian Contexts"],"award-info":[{"award-number":["Research on Health in Humanitarian Contexts"]}],"id":[{"id":"10.13039\/100012056","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["iwaponline.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Bucket chlorination, where chlorine is dosed directly into water collection containers, is a point-of-source water treatment intervention commonly implemented in cholera outbreaks. There is little previous data on chlorine efficacy against Vibrio cholerae in different waters and appropriate dosage regimes. We evaluated V. cholerae reduction and free chlorine residual (FCR) in waters with four turbidities (1\/5\/10\/50 NTU), two total organic carbon (TOC) concentrations (0.4, 1 mg\/L), and two dosing schemes (fixed-dose of 2 or 4 mg\/L, variable-dose based on jar testing) treated with three chlorine types (HTH, NaOCl, NaDCC). We found that chlorine was efficacious at reducing V. cholerae by \u22652.75 to \u22653.63 log reduction value (LRV); variably dosed reactors were dosed higher, met \u22650.5 mg\/L FCR at 30 min, and had higher LRVs (p=0.024) than fixed doses; and low TOC reactors had more samples \u22650.2 mg\/L FRC at 4 h (p=0.007). Our results are conservative, as internationally recommended additives to create test water increased chlorine demand, highlighting the challenge of replicating field conditions in laboratory testing. Overall, we found that chlorine can efficaciously reduce V. cholerae; we recommend further research on appropriate chlorine demand for test waters; and we recommend establishing appropriate chlorine doses based on source water and taste\/odor acceptability in bucket chlorination programs.<\/jats:p>","DOI":"10.2166\/wh.2022.043","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T03:30:56Z","timestamp":1656646256000},"page":"1071-1083","update-policy":"https:\/\/doi.org\/10.2166\/iwapcrossmarkpolicypage","source":"Crossref","is-referenced-by-count":3,"title":["Laboratory evaluation of the efficacy of bucket chlorination guidelines at inactivating <i>Vibrio cholerae<\/i> for waters of varying quality"],"prefix":"10.2166","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0266-923X","authenticated-orcid":false,"given":"Gabrielle M.","family":"String","sequence":"first","affiliation":[{"name":"a Tufts University School of Engineering, Medford, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie","family":"Huang","sequence":"additional","affiliation":[{"name":"b Tufts University School of Arts and Sciences, Medford, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Lantagne","sequence":"additional","affiliation":[{"name":"a Tufts University School of Engineering, Medford, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"945","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"key":"key-10.2166\/wh.2022.043-1","unstructured":"ACF 2013 EAU \u2013 Assainissment \u2013 Hygiene dans la Lutte Contre le Cholera 107."},{"key":"key-10.2166\/wh.2022.043-2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003832"},{"key":"key-10.2166\/wh.2022.043-3","doi-asserted-by":"publisher","DOI":"10.3362\/1756-3488.2017.002"},{"key":"key-10.2166\/wh.2022.043-4","unstructured":"CAWST 2021 Aquatabs [WWW Document]. 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