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During the operation of the reactor, the hydraulic retention time was progressively reduced from 4.8 to 1.6 days while achieving an average organic loading rate of 12.46 kg chemical oxygen demand (COD)\/(m3\u00b7d). Moreover, the removal rate of COD exceeded 98%, and the energy balance (\u0394E) reached 10.29 kJ\/g fed COD. The initial manifestation of organic acidosis in the reactor was a decline in gas production, which is primarily caused by propionic acid accumulation. The subsequent analysis revealed a high diversity of prokaryotes in granular sludge, with the predominant archaea primarily involved in methane production through the acetic acid pathway. The IC anaerobic reactor shows exceptional performance in treating corn alcohol wastewater by optimizing its operating conditions. Energy balance analysis confirmed the feasibility of the process. The findings of this study may offer valuable insights for optimizing control strategies and engineering applications.<\/jats:p>","DOI":"10.2166\/wst.2023.397","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T16:17:51Z","timestamp":1702052271000},"page":"3129-3141","update-policy":"https:\/\/doi.org\/10.2166\/iwapcrossmarkpolicypage","source":"Crossref","is-referenced-by-count":5,"title":["Study on the treatment of corn alcohol wastewater by the internal circulation anaerobic reactor"],"prefix":"10.2166","volume":"88","author":[{"given":"Junlin","family":"Ji","sequence":"first","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"},{"name":"b Economic Crop Technology Extension Station, Agricultural and Rural Bureau of Honghe Hani and Yi Autonomous Prefecture, Mengzi 661100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqin","family":"Xu","sequence":"additional","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"},{"name":"c College of Biological and Agricultural Science, Honghe University, Mengzi 661100, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Yang","sequence":"additional","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changmei","family":"Wang","sequence":"additional","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9744-1723","authenticated-orcid":false,"given":"Fang","family":"Yin","sequence":"additional","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wudi","family":"Zhang","sequence":"additional","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumei","family":"Hao","sequence":"additional","affiliation":[{"name":"a School of Energy and Environment Science, Yunnan Normal University, Kunming 650500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"945","published-online":{"date-parts":[[2023,12,8]]},"reference":[{"key":"key-10.2166\/wst.2023.397-1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2021.125027"},{"key":"key-10.2166\/wst.2023.397-2","doi-asserted-by":"publisher","DOI":"10.1007\/s10311-022-01435-8"},{"issue":"5","key":"key-10.2166\/wst.2023.397-3","first-page":"78","article-title":"IC acidification and recovery measures of internal cycle reactor treating canned fruit wastewater","volume":"35","author":"Guan","year":"2019","journal-title":"China Water & Wastewater"},{"key":"key-10.2166\/wst.2023.397-4","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s12571-021-01212-5","article-title":"Impacts of China's bioethanol policy on the global maize market: A partial equilibrium analysis to 2030","volume":"14","author":"Han","year":"2022","journal-title":"Food Security"},{"key":"key-10.2166\/wst.2023.397-5","doi-asserted-by":"publisher","DOI":"10.1080\/26395940.2019.1662734"},{"key":"key-10.2166\/wst.2023.397-6","unstructured":"Ji J. 2019 Anaerobic Treatment of Corn Alcohol Waste Water and Prokaryotic Microbial Community Analysis. 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