{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:33:34Z","timestamp":1793414014294,"version":"4.5.0"},"reference-count":18,"publisher":"Japanese Society of Internal Medicine","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2018,11,1]]},"DOI":"10.2169\/internalmedicine.0639-17","type":"journal-article","created":{"date-parts":[[2018,6,5]],"date-time":"2018-06-05T22:25:31Z","timestamp":1528237531000},"page":"3117-3122","source":"Crossref","is-referenced-by-count":4,"title":["Myxedema Coma Following the Administration of Gonadotropin-releasing Hormone Agonist Complicated by Acute Pancreatitis"],"prefix":"10.2169","volume":"57","author":[{"given":"Naoki","family":"Gocho","sequence":"first","affiliation":[{"name":"Diabetes Center, Ebina General Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ema","family":"Aoki","sequence":"additional","affiliation":[{"name":"Diabetes Center, Ebina General Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiho","family":"Okada","sequence":"additional","affiliation":[{"name":"Diabetes Center, Ebina General Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Hirashima","sequence":"additional","affiliation":[{"name":"Diabetes Center, Ebina General Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Wilson AC, Meethal SV, Bowen RL, Atwood CS. Leuprolide acetate: a drug of diverse clinical applications. Expert Opin Investig Drugs 16: 1851-1863, 2007.","DOI":"10.1517\/13543784.16.11.1851"},{"key":"2","unstructured":"2. Aoki C, Kasai K. The diagnosis and treatment of myxedema coma. Nihon Rinsho (Jpn J Clin Med) 70: 1995-1999, 2012 (in Japanese, Abstract in English)."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Eyal O, Rose SR. Autoimmune thyroiditis during leuprolide acetate treatment. J Pediatr 144: 394-396, 2004.","DOI":"10.1016\/j.jpeds.2003.11.036"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Kasayama S, Miyake S, Samejima Y. Transient thyrotoxicosis and hypothyroidism following administration of the GnRH agonist leuprolide acetate. Endocr J 47: 783-785, 2000.","DOI":"10.1507\/endocrj.47.783"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Han EJ, Song HD, Yang JH, et al. Thyroid dysfunction associated with administration of the long acting gonadotropin releasing hormone agonist. Endocrinol Metab (Seoul) 28: 221-225, 2013.","DOI":"10.3803\/EnM.2013.28.3.221"},{"key":"6","unstructured":"6. Matsuda M, Morita S, Arima T, Inoue I, Miyamura K. Buserelin induced painless thyroiditis. Naika (Int Med) 75: 363-364, 1995 (in Japanese)."},{"key":"7","doi-asserted-by":"publisher","unstructured":"7. Amino N, Hidaka Y, Takano T, Tatsumi KI, Izumi Y, Nakata Y. Possible induction of Graves&apos; disease and painless thyroiditis by gonadotropin-releasing hormone analogues. Thyroid 13: 815-818, 2003.","DOI":"10.1089\/105072503768499707"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Klubo-Gwiezdzinska J, Wartofsky L. Thyroid emergencies. Med Clin North Am 96: 385-403, 2012.","DOI":"10.1016\/j.mcna.2012.01.015"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Agarwal V, Parikh V, Otterbeck PE, Lafferty J. Myxedema coma induced by short-term amiodarone therapy. Am J Med Sci 347: 258-259, 2014.","DOI":"10.1097\/MAJ.0000000000000241"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Morote J, Esquena S, Orsola A, et al. Effect of androgen deprivation therapy in the thyroid function test of patients with prostate cancer. Anticancer Drugs 16: 863-866, 2005.","DOI":"10.1097\/01.cad.0000173474.82486.74"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Salminen E, Koskinen A, Backman H, Nurmi M. Effect of adjuvant androgen deprivation on thyroid function tests in prostate cancer patients. Anticancer Drugs 15: 351-356, 2004.","DOI":"10.1097\/00001813-200404000-00007"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Mathew V, Misgar RA, Ghosh S, et al. Myxedema coma: a new look into an old crisis. J Thyroid Res 2011: 493462, 2011.","DOI":"10.4061\/2011\/493462"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Maclean D, Murison J, Griffiths PD. Acute pancreatitis and diabetic ketoacidosis in accidental hypothermia and hypothermic myxoedema. Br Med J 4: 757-761, 1973.","DOI":"10.1136\/bmj.4.5895.757"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Stiff RE, Morris-Stiff GJ, Torkington J. Hypothermia and acute pancreatitis: myth or reality? J R Soc Med 96: 228-229, 2003.","DOI":"10.1177\/014107680309600506"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Alty JE, Ford HL. Multi-system complications of hypothermia: a case of recurrent episodic hypothermia with a review of the pathophysiology of hypothermia. Postgrad Med J 84: 282-286, 2008.","DOI":"10.1136\/pgmj.2007.066050"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Preuss J, Lignitz E, Dettmeyer R, Madea B. Pancreatic changes in cases of death due to hypothermia. Forensic Sci Int 166: 194-198, 2007.","DOI":"10.1016\/j.forsciint.2006.05.034"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Warshaw AL, O&apos;Hara PJ. Susceptibility of the pancreas to ischemic injury in shock. Ann Surg 188: 197-201, 1978.","DOI":"10.1097\/00000658-197808000-00012"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Zhou ZG, Chen YD. Influencing factors of pancreatic microcirculatory impairment in acute pancreatitis. World J Gastroenterol 8: 406-412, 2002.","DOI":"10.3748\/wjg.v8.i3.406"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/57\/21\/57_0639-17\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,3]],"date-time":"2018-11-03T05:16:08Z","timestamp":1541222168000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/57\/21\/57_0639-17\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,1]]},"references-count":18,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.0639-17","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,1]]}}}