{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T19:48:28Z","timestamp":1779306508956,"version":"3.51.4"},"reference-count":22,"publisher":"Japanese Society of Internal Medicine","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2018,9,15]]},"DOI":"10.2169\/internalmedicine.0696-17","type":"journal-article","created":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T18:24:51Z","timestamp":1524767091000},"page":"2727-2734","source":"Crossref","is-referenced-by-count":14,"title":["A Punctate Magnetic Resonance Imaging Pattern in a Patient with Systemic Lupus Erythematosus Is an Early Sign of Progressive Multifocal Leukoencephalopathy: A Clinicopathological Study"],"prefix":"10.2169","volume":"57","author":[{"given":"Junko","family":"Ishii","sequence":"first","affiliation":[{"name":"Department of Neurology, Kobe City Medical Center General Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Shishido-Hara","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology, Tokyo Medical University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michi","family":"Kawamoto","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kobe City Medical Center General Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kobe City Medical Center General Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kobe City Medical Center General Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Nakamichi","sequence":"additional","affiliation":[{"name":"Department of Virology 1, National Institute of Infectious Diseases, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Kohara","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kobe City Medical Center General Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Tan CS, Koralnik IJ. Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis. Lancet Neurol 9: 425-437, 2010.","DOI":"10.1016\/S1474-4422(10)70040-5"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. White MK, Khalili K. Pathogenesis of progressive multifocal leukoencephalopathy--revisited. J Infect Dis 203: 578-586, 2011.","DOI":"10.1093\/infdis\/jiq097"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Shishido-Hara Y. Progressive multifocal leukoencephalopathy and promyelocytic leukemia nuclear bodies: a review of clinical, neuropathological, and virological aspects of JC virus-induced demyelinating disease. Acta Neuropathol 120: 403-417, 2010.","DOI":"10.1007\/s00401-010-0694-x"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Schwab N, Schneider-Hohendorf T, Melzer N, Cutter G, Wiendl H. Natalizumab-associated PML: challenges with incidence, resulting risk, and risk stratification. Neurology 88: 1197-1205, 2017.","DOI":"10.1212\/WNL.0000000000003739"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5. Henegar CE, Eudy AM, Kharat V, Hill DD, Bennett D, Haight B. Progressive multifocal leukoencephalopathy in patients with systemic lupus erythematosus: a systematic literature review. Lupus 25: 617-626, 2016.","DOI":"10.1177\/0961203315622819"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Sahraian MA, Radue EW, Eshaghi A, Besliu S, Minagar A. Progressive multifocal leukoencephalopathy: a review of the neuroimaging features and differential diagnosis. Eur J Neurol 19: 1060-1069, 2012.","DOI":"10.1111\/j.1468-1331.2011.03597.x"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Phan-Ba R, Lommers E, Tshibanda L, et al. MRI preclinical detection and asymptomatic course of a progressive multifocal leucoencephalopathy (PML) under natalizumab therapy. J Neurol Neurosurg Psychiatry 83: 224-226, 2012.","DOI":"10.1136\/jnnp-2011-300511"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Hodel J, Darchis C, Outteryck O, et al. Punctate pattern: a promising imaging marker for the diagnosis of natalizumab-associated PML. Neurology 86: 1516-1523, 2016.","DOI":"10.1212\/WNL.0000000000002586"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Wijburg MT, Witte BI, Vennegoor A, et al. MRI criteria differentiating asymptomatic PML from new MS lesions during natalizumab pharmacovigilance. J Neurol Neurosurg Psychiatry 87: 1138-1145, 2016.","DOI":"10.1136\/jnnp-2016-313772"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Hodel J, Outteryck O, Dubron C, et al. Asymptomatic progressive multifocal leukoencephalopathy associated with natalizumab: diagnostic precision with MR imaging. Radiology 278: 863-872, 2016.","DOI":"10.1148\/radiol.2015150673"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Bertsias GK, Boumpas DT. Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations. Nat Rev Rheumatol 6: 358-367, 2010.","DOI":"10.1038\/nrrheum.2010.62"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Jennings JE, Sundgren PC, Attwood J, McCune J, Maly P. Value of MRI of the brain in patients with systemic lupus erythematosus and neurologic disturbance. Neuroradiology 46: 15-21, 2004.","DOI":"10.1007\/s00234-003-1049-2"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Plavina T, Subramanyam M, Bloomgren G, et al. Anti-JC virus antibody levels in serum or plasma further define risk of natalizumab-associated progressive multifocal leukoencephalopathy. Ann Neurol 76: 802-812, 2014.","DOI":"10.1002\/ana.24286"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Brandao M, Damasio J, Marinho A, et al. Systemic lupus erythematosus, progressive multifocal leukoencephalopathy, and T-CD4+ lymphopenia. Clin Rev Allergy Immunol 43: 302-307, 2012.","DOI":"10.1007\/s12016-012-8327-x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Wattjes MP, Verhoeff L, Zentjens W, et al. Punctate lesion pattern suggestive of perivascular inflammation in acute natalizumab-associated progressive multifocal leukoencephalopathy: productive JC virus infection or preclinical PML-IRIS manifestation? J Neurol Neurosurg Psychiatry 84: 1176-1177, 2013.","DOI":"10.1136\/jnnp-2013-304986"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Fredericks CA, Kvam KA, Bear J, Crabtree GS, Josephson SA. A case of progressive multifocal leukoencephalopathy in a lupus patient treated with belimumab. Lupus 23: 711-713, 2014.","DOI":"10.1177\/0961203314524292"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Beppu M, Kawamoto M, Nukuzuma S, Kohara N. Mefloquine improved progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus. Intern Med 51: 1245-1247, 2012.","DOI":"10.2169\/internalmedicine.51.6810"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Sinnecker T, Othman J, Kuhl M, et al. 7T MRI in natalizumab-associated PML and ongoing MS disease activity: a case study. Neurol Neuroimmunol Neuroinflamm 2: e171, 2015.","DOI":"10.1212\/NXI.0000000000000171"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Gieselbach RJ, Muller-Hansma AH, Wijburg MT, et al. Progressive multifocal leukoencephalopathy in patients treated with fumaric acid esters: a review of 19 cases. J Neurol 264: 1155-1164, 2017.","DOI":"10.1007\/s00415-017-8509-9"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Bartsch T, Rempe T, Wrede A, et al. Progressive neurologic dysfunction in a psoriasis patient treated with dimethyl fumarate. Ann Neurol 78: 501-514, 2015.","DOI":"10.1002\/ana.24471"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Shishido-Hara Y, Yazawa T, Nagane M, et al. JC virus inclusions in progressive multifocal leukoencephalopathy: scaffolding promyelocytic leukemia nuclear bodies grow with cell cycle transition through an S-to-G2-like state in enlarging oligodendrocyte nuclei. J Neuropathol Exp Neurol 73: 442-453, 2014.","DOI":"10.1097\/NEN.0000000000000066"},{"key":"22","doi-asserted-by":"publisher","unstructured":"22. Berger JR, Aksamit AJ, Clifford DB, et al. PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section. Neurology 80: 1430-1438, 2013.","DOI":"10.1212\/WNL.0b013e31828c2fa1"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/57\/18\/57_0696-17\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T01:09:43Z","timestamp":1537060183000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/57\/18\/57_0696-17\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,15]]},"references-count":22,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.0696-17","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,15]]}}}