{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T18:01:03Z","timestamp":1759341663951},"reference-count":17,"publisher":"Japanese Society of Internal Medicine","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2019,1,1]]},"DOI":"10.2169\/internalmedicine.0843-18","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T18:36:39Z","timestamp":1535049399000},"page":"67-71","source":"Crossref","is-referenced-by-count":3,"title":["Accelerated Progression of Hepatocellular Carcinoma during Immunosuppressive Therapy with Abatacept for Rheumatoid Arthritis"],"prefix":"10.2169","volume":"58","author":[{"given":"Satoshi","family":"Yoshiji","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Sawada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Mishima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Eso","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Morita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Takai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Marusawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihide","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuneyo","family":"Mimori","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Seno","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Genovese MC, Becker JC, Schiff M, et al. Abatacept for rheumatoid arthritis refractory to tumor necrosis factor \u03b1 inhibition. New Engl J Med 353: 1114-1123, 2005.","DOI":"10.1056\/NEJMoa050524"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Westhovens R, Robles M, Ximenes AC, et al. Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors. Ann Rheum Dis 68: 1870-1877, 2009.","DOI":"10.1136\/ard.2008.101121"},{"key":"3","unstructured":"3. Gartlehner G, Hansen RA, Jonas BL, Thieda P, Lohr KN. The comparative efficacy and safety of biologics for the treatment of rheumatoid arthritis: a systematic review and metaanalysis. J Rheumatol 33: 2398-2408, 2006."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Lipson EJ, Drake CG. Ipilimumab: an anti-CTLA-4 antibody for metastatic melanoma. Clin Cancer Res 17: 6958-6962, 2011.","DOI":"10.1158\/1078-0432.CCR-11-1595"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Weinblatt M, Combe B, Covucci A, Aranda R, Becker JC, Keystone E. Safety of the selective costimulation modulator abatacept in rheumatoid arthritis patients receiving background biologic and nonbiologic disease modifying antirheumatic drugs: a one year randomized, placebo-controlled study. Arthritis Rheumatol 54: 2807-2816, 2006.","DOI":"10.1002\/art.22070"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Kremer JM, Genant HK, Moreland LW, et al. Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial. Ann Intern Med 144: 865-876, 2006.","DOI":"10.7326\/0003-4819-144-12-200606200-00003"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Simon TA, Smitten AL, Franklin J, et al. Malignancies in the rheumatoid arthritis abatacept clinical development programme: an epidemiological assessment. Ann Rheum Dis 68: 1819-1826, 2009.","DOI":"10.1136\/ard.2008.097527"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Koda M, Maeda Y, Matsunaga Y, et al. Hepatocellular carcinoma with sarcomatous change arising after radiofrequency ablation for well-differentiated hepatocellular carcinoma. Hepatol Res 27: 163-167, 2003.","DOI":"10.1016\/S1386-6346(03)00207-9"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Wegener's GE. Etanercept plus standard therapy for Wegener's granulomatosis. New Engl J Med 352: 351-361, 2005.","DOI":"10.1056\/NEJMoa041884"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Duffy AG, Ulahannan SV, Makorova-Rusher O, et al. Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma. J Hepatol 66: 545-551, 2017.","DOI":"10.1016\/j.jhep.2016.10.029"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Corcorran MA, Olson JM, Hecht C, Knezevich S, Vary JC. Eruptive squamous cell carcinoma in a patient receiving abatacept for rheumatoid arthritis. J Am Acad Dermatol 69: e178-e179, 2013.","DOI":"10.1016\/j.jaad.2013.04.018"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Olivo D, Grembiale RD, Tallarigo F, Russo E, De Sarro G, Ursini F. Kaposi's sarcoma after T-cell costimulation blockade with abatacept in rheumatoid arthritis: a case report. J Clin Pharm Ther 42: 367-369, 2017.","DOI":"10.1111\/jcpt.12510"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Deidda A, Pisanu C, Garau D, et al. Squamous cell carcinoma of the tongue following therapy of rheumatoid arthritis with abatacept. Clin Case Rep 2: 66-69, 2014.","DOI":"10.1002\/ccr3.56"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Kumar A, Le DT. Hepatocellular carcinoma regression after cessation of immunosuppressive therapy. J Clin Oncol 34: e90-e92, 2014.","DOI":"10.1200\/JCO.2013.51.4067"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15. Shiina S, Teratani T, Obi S, et al. A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma. Gastroenterology 129: 122-130, 2005.","DOI":"10.1053\/j.gastro.2005.04.009"},{"key":"16","doi-asserted-by":"publisher","unstructured":"16. El-Serag HB. Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 142: 1264-1273, 2012.","DOI":"10.1053\/j.gastro.2011.12.061"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Crispe IN. Immune tolerance in liver disease. Hepatology 60: 2109-2117, 2014.","DOI":"10.1002\/hep.27254"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/58\/1\/58_0843-18\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,5]],"date-time":"2019-01-05T00:11:43Z","timestamp":1546647103000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/58\/1\/58_0843-18\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.0843-18","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,1]]}}}