{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T03:58:38Z","timestamp":1763179118269},"reference-count":20,"publisher":"Japanese Society of Internal Medicine","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2019,3,15]]},"DOI":"10.2169\/internalmedicine.1246-18","type":"journal-article","created":{"date-parts":[[2019,3,14]],"date-time":"2019-03-14T22:46:11Z","timestamp":1552603571000},"page":"849-854","source":"Crossref","is-referenced-by-count":9,"title":["Recurrent Epstein-Barr Virus-positive (EBV+) Primary Central Nervous System Lymphoma (PCNSL) in a Patient with Clinical Features of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS)"],"prefix":"10.2169","volume":"58","author":[{"given":"Masahiro","family":"Nagano","sequence":"first","affiliation":[{"name":"Department of Neurology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Ayaki","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsuko","family":"Koita","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyuki","family":"Kitano","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Momoko","family":"Nishikori","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Goda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Minamiguchi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kyoto University Graduate School of Medicine, Japan"},{"name":"Department of Epilepsy, Movement Disorders and Physiology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akifumi","family":"Takaori-Kondo","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kyoto University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","unstructured":"1. Fraser E, Gruenberg K, Rubenstein JL. Rubenstein. New approaches in primary central nervous system lymphoma. Chin Clin Oncol 4: 11, 2015."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Pittock SJ, Debruyne J, Krecke KN, et al. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Brain 133: 2626-2634, 2010.","DOI":"10.1093\/brain\/awq164"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Limousin N, Praline J, Motica O, et al. Brain biopsy is required in steroid-resistant patients with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). J Neurooncol 107: 223-224, 2012.","DOI":"10.1007\/s11060-011-0724-0"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Taieb G, Uro-Coste E, Clanet M, et al. A central nervous system B-cell lymphoma arising two years after initial diagnosis of CLIPPERS. J Neurol Sci 344: 224-226, 2014.","DOI":"10.1016\/j.jns.2014.06.015"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Lin AW, Das S, Fraser JA, et al. Emergence of primary CNS lymphoma in a patient with findings of CLIPPERS. Can J Neurol Sci 41: 528-529, 2014.","DOI":"10.1017\/S0317167100018631"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6. Dudesek A, Rimmele F, Tesar S, et al. CLIPPERS: chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. Review of an increasingly recognized entity within the spectrum of inflammatory central nervous system disorders. Clin Exp Immunol 175: 385-396, 2014.","DOI":"10.1111\/cei.12204"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Poortmans PM, Kluin-Nelemans HC, Haaxma-Reiche H, et al. High-dose methotrexate-based chemotherapy followed by consolidating radiotherapy in non-aids-related primary central nervous system lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group phase II trial 20962. J Clin Oncol 24: 4483-4488, 2003.","DOI":"10.1200\/JCO.2003.03.108"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Manoj N, Arivazhagan A, Mahadevan A, et al. Central nervous system lymphoma: patterns of incidence in Indian population and effect of steroids on stereotactic biopsy yield. Neurol India 62: 19-25, 2014.","DOI":"10.4103\/0028-3886.128272"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Simon NG, Parratt JD, Barnett MH, et al. Expanding the clinical, radiological and neuropathological phenotype of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). J Neurol Neurosurg Psychiatry 83: 15-22, 2012.","DOI":"10.1136\/jnnp-2011-301054"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Weller M. Glucocorticoid treatment of primary CNS lymphoma. J Neuro-Oncol 43: 237-239, 1999.","DOI":"10.1023\/A:1006254518848"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Vaquero J, Martinez R, Rossi E, Lopez R. Primary cerebral lymphoma: the &quot;ghost tumor&quot; . J Neurosurg 60: 174-176, 1984.","DOI":"10.3171\/jns.1984.60.1.0174"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Alderson L, Fetell MR, Sisti M, Hochberg F, Cohen M, Louis DN. Sentinel lesions of primary CNS lymphoma. J Neurol Neurosurg Psychiatry 60: 102-105, 1996.","DOI":"10.1136\/jnnp.60.1.102"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Porter AB, Giannini C, Kaufmann T, et al. Primary central nervous system lymphoma can be histologically diagnosed after previous corticosteroid use: a pilot study to determine whether corticosteroids prevent the diagnosis of primary central nervous system lymphoma. Ann Neurol 63: 662-667, 2008.","DOI":"10.1002\/ana.21366"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Pirotte B, Levivier M, Goldman S, Brucher JM, Brotchi J, Hildebrand J. Glucocorticoid-induced long-term remission in primary cerebral lymphoma: case report and review of the literature. J Neurooncol 32: 63-69, 1997.","DOI":"10.1023\/A:1005733416571"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. De Graaff HJ, Wattjes MP, Rozemuller-Kwakkel AJ, Petzold A, Killestein J. Fatal B-cell lymphoma following chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids. JAMA Neurol 70: 915-918, 2013.","DOI":"10.1001\/jamaneurol.2013.2016"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Wang X, Huang D, Huang X, et al. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS): a lymphocytic reactive response of the central nervous system? a case report. J Neuroimmunol 305: 68-71, 2017.","DOI":"10.1016\/j.jneuroim.2017.01.014"},{"key":"17","unstructured":"17. Swerdlow SH, Campo E, Harris NL, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Revised 4th ed. International Agency for Research on Cancer, Lyon, 2017."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Niller H, Bauer G. Epstein-Barr virus: clinical diagnostics. In: Epstein Barr Virus: Methods and Protocols (Methods in Molecular Biology). 1st ed. Minarovits J, Niller H, Eds. Humana Press, Totowa, 2017: 33-55.","DOI":"10.1007\/978-1-4939-6655-4_2"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Ma Y, Sun X, Li W, et al. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) with intracranial Epstein-Barr virus infection. Medicine 95: 1-4, 2017.","DOI":"10.1097\/MD.0000000000005377"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Mashima K, Suzuki S, Mori T, et al. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) after treatment for Hodgkin&apos;s lymphoma. Int J Hematol 102: 709-712, 2015.","DOI":"10.1007\/s12185-015-1850-9"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/58\/6\/58_1246-18\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T15:45:59Z","timestamp":1574351159000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/58\/6\/58_1246-18\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,15]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.1246-18","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,15]]}}}