{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T19:59:08Z","timestamp":1783627148289,"version":"3.55.0"},"reference-count":29,"publisher":"Japanese Society of Internal Medicine","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2024,1,15]]},"DOI":"10.2169\/internalmedicine.1630-23","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T22:14:25Z","timestamp":1685484865000},"page":"259-264","source":"Crossref","is-referenced-by-count":1,"title":["Rare Coexistence of Aldosterone-producing Adrenocortical Adenoma Confirmed by an Immunohistochemical Analysis of Steroidogenic Enzymes with Adrenal Ectopic Thyroid Tissue: A Case Report and Literature Review"],"prefix":"10.2169","volume":"63","author":[{"given":"Yohsuke","family":"Ohkubo","sequence":"first","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Division of Internal Medicine, Shinshu University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Division of Internal Medicine, Shinshu University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuho","family":"Shimada","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Division of Internal Medicine, Shinshu University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Kubota","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Division of Internal Medicine, Shinshu University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohei","family":"Takayama","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Division of Internal Medicine, Shinshu University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ako","family":"Oiwa","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Division of Internal Medicine, Shinshu University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironobu","family":"Sasano","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tohoku University Graduate School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhisa","family":"Komatsu","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Division of Internal Medicine, Shinshu University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Ibrahim NA, Fadeyibi IO. Ectopic thyroid: etiology, pathology, and management. Hormones (Athens) 10: 261-269, 2011.","DOI":"10.14310\/horm.2002.1317"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Nanba K, Tsuiki M, Sawai K, et al. Histopathological diagnosis of primary aldosteronism using CYP11B2 immunohistochemistry. J Clin Endocrinol Metab 98: 1567-1574, 2013.","DOI":"10.1210\/jc.2012-3726"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Mete O, Erickson LA, Juhlin CC, et al. Overview of the 2022 WHO classification of adrenal cortical tumors. Endocr Pathol 33: 155-196, 2022.","DOI":"10.1007\/s12022-022-09710-8"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4. Omata K, Satoh F, Morimoto R, et al. Cellular and genetic causes of idiopathic hyperaldosteronism. Hypertension 72: 874-880, 2018.","DOI":"10.1161\/HYPERTENSIONAHA.118.11086"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Oelkers W, Diederich S, Bahr V. Primary hyperaldosteronism without suppressed renin due to secondary hypertensive kidney damage. J Clin Endocrinol Metab 85: 3266-3270, 2000.","DOI":"10.1210\/jcem.85.9.6819"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Catena C, Colussi G, Nadalini E, et al. Relationships of plasma renin levels with renal function in patients with primary aldosteronism. Clin J Am Soc Nephrol 2: 722-731, 2007.","DOI":"10.2215\/CJN.00050107"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Tsujimura A, Takaha M, Takayama H, Sugao H, Takeda M, Kurata A. Ectopic thyroid tissue in a cystic adrenal mass. Br J Urol 77: 605-606, 1996.","DOI":"10.1046\/j.1464-410X.1996.99026.x"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Shiraishi T, Imai H, Fukutome K, Watanabe M, Yatani R. Ectopic thyroid in the adrenal gland. Hum Pathol 30: 105-108, 1999.","DOI":"10.1016\/S0046-8177(99)90309-X"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Shuno Y, Kobayashi T, Morita K, et al. Ectopic thyroid in the adrenal gland presenting as cystic lesion. Surgery 139: 580-582, 2006.","DOI":"10.1016\/j.surg.2004.12.011"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Hagiuda J, Kuroda I, Tsukamoto T, et al. Ectopic thyroid in an adrenal mass: a case report. BMC Urol 6: 18, 2006.","DOI":"10.1186\/1471-2490-6-18"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Takao H, Doi I, Watanabe T. Ectopic thyroid in the adrenal gland: computed tomography findings. J Comput Assist Tomogr 30: 221-222, 2006.","DOI":"10.1097\/00004728-200603000-00009"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12. Bohinc BN, Parker JC, Hope WW, et al. Micropapillary thyroid carcinoma and concomitant ectopic thyroid tissue in the adrenal gland: metastasis or metaplasia? Thyroid 21: 1033-1038, 2011.","DOI":"10.1089\/thy.2010.0390"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Romero-Rojas A, Bella-Cueto MR, Meza-Cabrera IA, et al. Ectopic thyroid tissue in the adrenal gland: a report of two cases with pathogenetic implications. Thyroid 23: 1644-1650, 2013.","DOI":"10.1089\/thy.2013.0063"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Gourmaud J, Bongiovanni M, Triponez F, Pusztaszeri M. Ectopic thyroid tissue in the adrenal gland. Endocr Pathol 25: 353-355, 2014.","DOI":"10.1007\/s12022-013-9255-x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Casadei GP, Bertarelli C, Giorgini E, Cremonini N, de Biase D, Tallini G. Ectopic thyroid tissue in the adrenal gland: report of a case. Int J Surg Pathol 23: 170-175, 2015.","DOI":"10.1177\/1066896914541001"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Tada A, Tanaka T, Takamoto A, Yanai H, Sato S, Kanazawa S. Ectopic thyroid tissue in the adrenal gland: CT and MRI findings. Diagn Interv Imaging 97: 373-375, 2016.","DOI":"10.1016\/j.diii.2015.06.025"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Y\u0131lmaz BA, Akt\u00fcrk M, Kan E, et al. Ectopic thyroid in the adrenal presenting as an adrenal incidentaloma. Turk J Endocrinol Metab 20: 4, 2016.","DOI":"10.4274\/tjem.3153"},{"key":"18","unstructured":"18. Li H, Chen Q, Zhu Y, Mu Q, Cao Z, Wu S. Ectopic thyroid tissue in the adrenal gland: a case report with clinical and pathogenetic implications. Int J Clin Exp Pathol 10: 8761-8764, 2017."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Wang SC, Hung SW, Lee CH, Ho HC, Ou YC, Yang CK. Ectopic thyroid tissue in the adrenal gland mimicking a pheochromocytoma. J Endourol Case Rep 3: 149-151, 2017.","DOI":"10.1089\/cren.2017.0080"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Lin-Iin Z, Xiao-Qian Z, Lan-ping W, Ming J, Feng Z. Ectopic thyroid tissue in the adrenal gland: a case report and literature review. Hum Pathol Case Rep 21: 200386, 2020.","DOI":"10.1016\/j.ehpc.2020.200386"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Rawitzer J, Kapakoglou A, Walz MK, Schmid KW, Reis H. Ectopic thyroid tissue in the adrenal gland: a case report and review of the literature. Pathologe 41: 177-180, 2020.","DOI":"10.1007\/s00292-019-00724-4"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Paunovic I, Rovcanin B, Jovanovic M, Buzejic M, Dundjerovic D, Zivaljevic V. Ectopic thyroid tissue in adrenal gland, case report and review of literature. Gland Surg 9: 1573-1578, 2020.","DOI":"10.21037\/gs-20-471"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Huang CC, Kraft C, Moy N, Ng L, Forrest D. A novel population of inner cortical cells in the adrenal gland that displays sexually dimorphic expression of thyroid hormone receptor \u03b21. Endocrinology 156: 2338-2348, 2015.","DOI":"10.1210\/en.2015-1118"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Patyra K, L\u00f6f C, Jaeschke H, et al. Congenital hypothyroidism and hyperthyroidism alters adrenal gene expression, development, and function. Thyroid 32: 459-471, 2022.","DOI":"10.1089\/thy.2021.0535"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Williams TA, Gomez-Sanchez CE, Rainey WE, et al. International histopathology consensus for unilateral primary aldosteronism. J Clin Endocrinol Metab 106: 42-54, 2021.","DOI":"10.1210\/clinem\/dgaa484"},{"key":"26","unstructured":"26. Yamazaki Y, Nakamura Y, Omata K, et al. Histopathological classification of cross-sectional image - negative hyperaldosteronism. J Clin Endocrinol Metab 102: 1182-1192, 2017."},{"key":"27","unstructured":"27. LiVolsi VA. Surgical Pathology of the Thyroid. vol 22. W.B. Saunders, Philadelphia, PA, 1990."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Rossi ED, Martini M, Straccia P, Larocca LM, Fadda G. Detection of ectopic thyroid remnants: a serious diagnostic dilemma. When molecular biology and immunohistochemistry can solve the problem. Pathol Res Pract 209: 59-61, 2013.","DOI":"10.1016\/j.prp.2012.09.010"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Nikiforova MN, Lynch RA, Biddinger PW, et al. <i>RAS<\/i> point mutations and PAX8-PPAR\u03b3 rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma. J Clin Endocrinol Metab 88: 2318-2326, 2003.","DOI":"10.1210\/jc.2002-021907"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/63\/2\/63_1630-23\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T03:20:41Z","timestamp":1705720841000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/63\/2\/63_1630-23\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,15]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.1630-23","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,15]]},"article-number":"1630-23"}}