{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:55:27Z","timestamp":1790776527927,"version":"4.1.0"},"reference-count":29,"publisher":"Japanese Society of Internal Medicine","issue":"17","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2019,9,1]]},"DOI":"10.2169\/internalmedicine.2535-18","type":"journal-article","created":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T22:03:35Z","timestamp":1559858615000},"page":"2427-2433","source":"Crossref","is-referenced-by-count":25,"title":["Vonoprazan versus Lansoprazole for the Initial Treatment of Reflux Esophagitis: A Cost-effectiveness Analysis in Japan"],"prefix":"10.2169","volume":"58","author":[{"given":"Yasuki","family":"Habu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Saiseikai-Noe Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 63: 871-880, 2014.","DOI":"10.1136\/gutjnl-2012-304269"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Kinoshita Y, Adachi K, Hongo M, Haruma K. Systematic review of the epidemiology of gastroesophageal reflux disease in Japan. J Gastroenterol 46: 1092-1103, 2011.","DOI":"10.1007\/s00535-011-0429-3"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Iwakiri K, Kinoshita Y, Habu Y, et al. Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015. J Gastroenterol 51: 751-767, 2016.","DOI":"10.1007\/s00535-016-1227-8"},{"key":"4","unstructured":"4. Wahlqvist P, Reilly MC, Barkun A. Systematic review: the impact of gastro-oesophageal reflux disease on work productivity. Aliment Pharmacol Ther 24: 259-272, 2006."},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Peery AF, Crockett SD, Murphy CC, et al. Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2018. Gastroenterology 2018 (Epub ahead of print).","DOI":"10.1053\/j.gastro.2018.08.063"},{"key":"6","unstructured":"6. Habu Y, Maeda K, Kusuda T, et al.  "Proton-pump inhibitor-first" strategy versus "step-up" strategy for the acute treatment of reflux esophagitis: a cost-effectiveness analysis in Japan. J Gastroenterol 40: 1029-1035, 2005."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Gawron AJ, French DD, Pandolfino JE, Howden CW. Economic evaluations of gastroesophageal reflux disease medical management. Pharmacoeconomics 32: 745-758, 2014.","DOI":"10.1007\/s40273-014-0164-8"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol 108: 308-328, 2013.","DOI":"10.1038\/ajg.2012.444"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Inadomi JM, Jamal R, Murata GH, et al. Step-down management of gastroesophageal reflux disease. Gastroenterology 121: 1095-1100, 2001.","DOI":"10.1053\/gast.2001.28649"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Umezawa M, Kawami N, Hoshino S, et al. Efficacy of on-demand therapy using 20-mg vonoprazan for mild reflux esophagitis. Digestion 97: 309-315, 2018.","DOI":"10.1159\/000485795"},{"key":"11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1053\/j.gastro.2017.04.047","volume":"153","author":"MF Vaezi","year":"2017","unstructured":"11. Vaezi MF, Yang YX, Howden CW. Complications of proton pump inhibitor therapy. Gastroenterology 153: 35-48, 2017.","journal-title":"Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"key":"12","unstructured":"12. Choosing Wisely. Promoting conversations between patients and clinicians [Internet]. [cited 2018 Dec 12]. Available from: http:\/\/www.choosingwisely.org\/"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Sakurai Y, Mori Y, Okamoto H, et al. Acid-inhibitory effects of vonoprazan 20 mg compared with esomeprazole 20 mg or rabeprazole 10 mg in healthy adult male subjects-a randomised open-label cross-over study. Aliment Pharmacol Ther 42: 719-730, 2015.","DOI":"10.1111\/apt.13325"},{"key":"14","unstructured":"14. Ashida K, Sakurai Y, Hori T, et al. Randomised clinical trial: vonoprazan, a novel potassium-competitive acid blocker, vs. lansoprazole for the healing of erosive oesophagitis. Aliment Pharmacol Ther 43: 240-251, 2016."},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Beck JR, Pauker SG. The Markov process in medical prognosis. Med Decis Making 3: 419-458, 1983.","DOI":"10.1177\/0272989X8300300403"},{"key":"16","unstructured":"16. Pharmaceuticals and Medical Devices Agency [Internet]. [cited 2018 Dec 12]. Available from: http:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuSearch\/ (in Japanese)"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Sandmark S, Carlsson R, Fausa O, Lundell L. Omeprazole or ranitidine in the treatment of reflux esophagitis. Results of a double-blind, randomized, Scandinavian multicenter study. Scand J Gastroenterol 23: 625-632, 1988.","DOI":"10.3109\/00365528809093923"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Hetzel DJ, Dent J, Reed WD, et al. Healing and relapse of severe peptic esophagitis after treatment with omeprazole. Gastroenterology 95: 903-912, 1988.","DOI":"10.1016\/0016-5085(88)90162-X"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Bate CM, Booth SN, Crowe JP, et al. Omeprazole 10 mg or 20 mg once daily in the prevention of recurrence of reflux oesophagitis. Solo Investigator Group. Gut 36: 492-498, 1995.","DOI":"10.1136\/gut.36.4.492"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Robinson M, Lanza F, Avner D, Haber M. Effective maintenance treatment of reflux esophagitis with low-dose lansoprazole. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 124: 859-867, 1996.","DOI":"10.7326\/0003-4819-124-10-199605150-00001"},{"key":"21","unstructured":"21. Hegarty JH, Halvorsen L, Hazenberg BP, et al. Prevention of relapse in reflux esophagitis: a placebo controlled study of ranitidine 150 mg bid and 300 mg bid. Can J Gastroenterol 11: 83-88, 1997."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Sonnenberg A. Costs of medical and surgical treatment of duodenal ulcer. Gastroenterology 96: 1445-1452, 1989.","DOI":"10.1016\/0016-5085(89)90511-8"},{"key":"23","unstructured":"23. Sakaguchi M, Ashida K, Habu Y, et al. Understanding and treatment of gastroesophageal reflux disease (GERD) and symptomatic gastroesophageal reflux disease (S-GERD): Examination by a questionnaire survey. Gastroenterology (Tokyo) 39: 330-340, 2004 (in Japanese, Abstract in English)."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Kantor ED, Rehm CD, Haas JS, Chan AT, Giovannucci EL. Trends in prescription drug use among adults in the United States from 1999-2012. JAMA 314: 1818-1831, 2015.","DOI":"10.1001\/jama.2015.13766"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Schumock GT, Li EC, Suda KJ, et al. National trends in prescription drug expenditures and projections for 2016. Am J Health Syst Pharm 73: 1058-1075, 2016.","DOI":"10.2146\/ajhp160205"},{"key":"26","unstructured":"26. Shimatani T, Inoue M, Kuroiwa T, Xu J, Mieno H, Tazuma S. Acid-suppressive effects of generic omeprazole: comparison of three brands of generic omeprazole with original omeprazole. Dig Liver Dis 38: 554-559, 2006."},{"key":"27","unstructured":"27. Shimatani T, Hirokawa S, Tawara Y, et al. Comparing the acid-suppressive effects of three brands of generic lansoprazole with the original: pharmacokinetic bioequivalence tests do not necessarily guarantee pharmacodynamic equivalence. Dig Dis Sci 54: 2385-2390, 2009."},{"key":"28","doi-asserted-by":"publisher","unstructured":"28. Chiba N, De Gara CJ, Wilkinson JM, Hunt RH. Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis. Gastroenterology 112: 1798-1810, 1997.","DOI":"10.1053\/gast.1997.v112.pm9178669"},{"key":"29","unstructured":"29. Kassirer JP, Moskowitz AJ, Lau J, Pauker SG. Decision analysis: a progress report. Ann Intern Med 106: 275-291, 1987."}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/58\/17\/58_2535-18\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,7]],"date-time":"2019-09-07T03:42:10Z","timestamp":1567827730000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/58\/17\/58_2535-18\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,1]]},"references-count":29,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.2535-18","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,1]]}}}