{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:15:13Z","timestamp":1768583713571,"version":"3.49.0"},"reference-count":17,"publisher":"Japanese Society of Internal Medicine","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2020,6,15]]},"DOI":"10.2169\/internalmedicine.4265-19","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T22:05:33Z","timestamp":1584569133000},"page":"1549-1553","source":"Crossref","is-referenced-by-count":2,"title":["Accelerated Phase of Atypical Chronic Myeloid Leukemia with Severe Disseminated Intravascular Coagulation at Initial Presentation"],"prefix":"10.2169","volume":"59","author":[{"given":"Mai","family":"Fujita","sequence":"first","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuharu","family":"Kamachi","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Yokoo","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Kidoguchi","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kana","family":"Kusaba","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruna","family":"Kizuka-Sano","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyosuke","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsujiro","family":"Nishioka","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Kubota","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"},{"name":"Department of Transfusion Medicine, Saga University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Ando","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensuke","family":"Kojima","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"},{"name":"Department of Hematology, Kochi Medical School, Kochi University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Kimura","sequence":"additional","affiliation":[{"name":"Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 127: 2391-2405, 2016.","DOI":"10.1182\/blood-2016-03-643544"},{"key":"2","first-page":"1566","volume":"91","author":"M Breccia","year":"2006","unstructured":"2. Breccia M, Biondo F, Latagliata R, et al. Identification of risk factors in atypical chronic myeloid leukemia. Haematologica 91: 1566-1568, 2006.","journal-title":"Haematologica","ISSN":"https:\/\/id.crossref.org\/issn\/0390-6078","issn-type":"print"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Schwartz LC, Mascarenhas J. Current and evolving understanding of atypical chronic myeloid leukemia. Blood Rev 33: 74-81, 2019.","DOI":"10.1016\/j.blre.2018.07.004"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Kojima K, Omoto E, Hara M, et al. Myelodysplastic syndrome with translocation (8;21): a distinct myelodysplastic syndrome entity or M2-acute myeloid leukemia with extensive myeloid maturation? Ann Hematol 76: 279-282, 1998.","DOI":"10.1007\/s002770050402"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Miyamoto T, Weissman IL, Akashi K. AML1\/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation. Proc Natl Acad Sci U S A 97: 7521-7526, 2000.","DOI":"10.1073\/pnas.97.13.7521"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6. Pardanani A, Lasho TL, Laborde RR, et al. CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia. Leukemia 27: 1870-1873, 2013.","DOI":"10.1038\/leu.2013.122"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7. Theocharides A, Boissinot M, Girodon F, et al. Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation. Blood 110: 375-379, 2007.","DOI":"10.1182\/blood-2006-12-062125"},{"key":"8","doi-asserted-by":"publisher","unstructured":"8. Wang SA, Hasserjian RP, Fox PS, et al. Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic\/myeloproliferative neoplasms. Blood 123: 2645-2651, 2014.","DOI":"10.1182\/blood-2014-02-553800"},{"key":"9","doi-asserted-by":"publisher","unstructured":"9. Meggendorfer M, Haferlach T, Alpermann T, et al. Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia. Haematologica 99: e244-e246, 2014.","DOI":"10.3324\/haematol.2014.113159"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Zoi K, Cross NCP. Molecular pathogenesis of atypical CML, CMML and MDS\/MPN-unclassifiable. Int J Hematol 101: 229-242, 2015.","DOI":"10.1007\/s12185-014-1670-3"},{"key":"11","unstructured":"11. Langabeer SE. The mutational landscape of atypical chronic myeloid leukemia. EXCLI J 18: 256-258, 2019."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Piazza R, Valletta S, Winkelmann N, et al. Recurrent SETBP1 mutations in atypical chronic myeloid leukemia. Nat Genet 45: 18-24, 2013.","DOI":"10.1038\/ng.2495"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Patnaik MM, Barraco D, Lasho TL, et al. Targeted next generation sequencing and identification of risk factors in World Health Organization defined atypical chronic myeloid leukemia. Am J Hematol 92: 542-548, 2017.","DOI":"10.1002\/ajh.24722"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Gambacorti-Passerini CB, Donadoni C, Parmiani A, et al. Recurrent ETNK1 mutations in atypical chronic myeloid leukemia. Blood 125: 499-503, 2015.","DOI":"10.1182\/blood-2014-06-579466"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Ley TJ, Miller C, Ding L, et al.; Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 368: 2059-2074, 2013.","DOI":"10.1056\/NEJMoa1301689"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Brunetti L, Gundry MC, Goodell MA. New insights into the biology of acute myeloid leukemia with mutated NPM1. Int J Hematol 110: 150-160, 2019.","DOI":"10.1007\/s12185-018-02578-7"},{"key":"17","unstructured":"17. Ali AM, Mirrakhimov AE, Abboud CN, Cashen AF. Leukostasis in adult acute hyperleukocytic leukemia: a clinician's digest. Hematol Oncol 34: 69-78, 2016."}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/59\/12\/59_4265-19\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,20]],"date-time":"2020-06-20T03:30:12Z","timestamp":1592623812000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/59\/12\/59_4265-19\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,15]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4265-19","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,15]]}}}