{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T03:10:26Z","timestamp":1774408226209,"version":"3.50.1"},"reference-count":19,"publisher":"Japanese Society of Internal Medicine","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2025,6,1]]},"DOI":"10.2169\/internalmedicine.4347-24","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T22:11:50Z","timestamp":1731017510000},"page":"1633-1639","source":"Crossref","is-referenced-by-count":2,"title":["Ulcerative Colitis in Pregnancy: A Japanese Multicenter Cohort Study Focusing on Their Mutual Influence"],"prefix":"10.2169","volume":"64","author":[{"given":"Yuichi","family":"Shimodate","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Inflammatory Bowel Disease Center, Kurashiki Central Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Shiotani","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kawasaki Medical School, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken-ichi","family":"Tarumi","sequence":"additional","affiliation":[{"name":"Inflammatory Bowel Disease Center, Chikuba Hospital for Gastrointestinal and Colorectal Surgery, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kawasaki Medical School, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Handa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Kawasaki Medical School, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriaki","family":"Tomioka","sequence":"additional","affiliation":[{"name":"Department of Surgery, Watanabe Gastrointestinal and Surgical Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoyuki","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Inflammatory Bowel Disease Center, Kurashiki Central Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Matsueda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Inflammatory Bowel Disease Center, Kurashiki Central Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Mouri","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Inflammatory Bowel Disease Center, Kurashiki Central Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motowo","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Inflammatory Bowel Disease Center, Kurashiki Central Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Kim MA, Kim YH, Chun J, et al. The influence of disease activity on pregnancy outcomes in women with inflammatory bowel disease: a systematic review and meta-analysis. J Crohns Colitis 15: 719-732, 2021.","DOI":"10.1093\/ecco-jcc\/jjaa225"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Ikeda A, Kunisaki R, Aoki S, et al. Appropriate preconception corticosteroid-free remission period in pregnant women with ulcerative colitis. Inflamm Bowel Dis 30: 726-734, 2024.","DOI":"10.1093\/ibd\/izac270"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Takahashi S, Kakuta Y, Obara T, et al. Prescribing in pregnant women with inflammatory bowel disease and its relationship to congenital malformations in Japan. J Gastroenterol Hepatol 39: 1291-1298, 2024.","DOI":"10.1111\/jgh.16549"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Kawai Y, Tsuchiya T, Aoki S. Pregnancy outcomes of patients exposed to adalimumab in Japan. Dig Dis 37: 123-130, 2019.","DOI":"10.1159\/000493462"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5. Mahadevan U, Long MD, Kane SV, et al; Crohn&apos;s Colitis Foundation Clinical Research Alliance. Pregnancy and neonatal outcomes after fetal exposure to biologics and thiopurines among women with inflammatory bowel disease. Gastroenterology 160: 1131-1139, 2021.","DOI":"10.1053\/j.gastro.2020.11.038"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Julsgaard M, N\u00f8rgaard M, Hvas CL, Buck D, Christensen LA. Self-reported adherence to medical treatment beforeand during pregnancy among women withulcerative colitis. Inflamm Bowel Dis 17: 1573-1580, 2011.","DOI":"10.1002\/ibd.21522"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Watanabe T, Nagahori M, Fujii T, et al. Non-adherence to medications in pregnant ulcerative colitis patients contributes to disease flares and adverse pregnancy outcomes. Dig Dis Sci 66: 577-586, 2021.","DOI":"10.1007\/s10620-020-06221-6"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med 317: 1625-1629, 1987.","DOI":"10.1056\/NEJM198712243172603"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Magro F, Gionchetti P, Eliakim R, et al; the European Crohn&apos;s and Colitis Organisation [ECCO]. Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 1: definitions, diagnosis, extra-intestinal manifestations, pregnancy, cancer surveillance, surgery, and ileo-anal pouch disorders. J Crohns Colitis 11: 649-670, 2017.","DOI":"10.1093\/ecco-jcc\/jjx008"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Ito A, Iizuka B, Omori T, Nakamura S, Tokushige K. Relationship between the clinical course of ulcerative colitis during pregnancy and the outcomes of pregnancy: a retrospective evaluation. Intern Med 57: 159-164, 2018.","DOI":"10.2169\/internalmedicine.8550-16"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Miler JP. Inflammatory bowel disease in pregnancy: a review. J R Soc Med 79: 221-225, 1986.","DOI":"10.1177\/014107688607900410"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Alstead EM. Inflammatory bowel disease in pregnancy. Postgrad Med J 78: 23-26, 2002.","DOI":"10.1136\/pmj.78.915.23"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Komoto S, Motoya S, Nishiwaki Y, et al; Japanese study group for pregnant women with IBD. Pregnancy outcome in women with inflammatory bowel disease treated with anti-tumor necrosis factor and\/or thiopurine therapy: a multicenter study from Japan. Intest Res 14: 139-145, 2016.","DOI":"10.5217\/ir.2016.14.2.139"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Kammerlander H, Nielsen J, Kjeldsen J, Knudsen T, Friedman S, N\u00f8rg\u00e5rd B. The effect of disease activity on birth outcomes in a nationwide cohort of women with moderate to severe inflammatory bowel disease. Inflamm Bowel Dis 23: 1011-1018, 2017.","DOI":"10.1097\/MIB.0000000000001102"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Yu A, Friedman S, Ananthakrishnan AN. Incidence and predictors of flares in the postpartum year among women with inflammatory bowel disease. Inflamm Bowel Dis 26: 1926-1932, 2020.","DOI":"10.1093\/ibd\/izz313"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Koslowsky B, Grisaru-Granovsky S, Livovsky DM, Milgrom Y, Goldin E, Bar-Gil Shitrit A. Pregnancy-onset inflammatory disease: subtle diagnosis. Inflamm Bowel Dis 24: 1826-1832, 2018.","DOI":"10.1093\/ibd\/izy081"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Padhan K, Kedia S, Kumar Garg S, et al. Long-term disease course and pregnancy outcomes in women with inflammatory bowel disease: an indian cohort study. Dig Dis Sci 62: 2054-2062, 2017.","DOI":"10.1007\/s10620-016-4353-5"},{"key":"18","doi-asserted-by":"publisher","unstructured":"18. Brunelli R, Perrone S, Perrone G, et al. New-onset ulcerative colitis in pregnancy associated to toxic megacolon and sudden fetal decompensation: case report and literature review. J Obstet Gynaecol Res 45: 1215-1221, 2019.","DOI":"10.1111\/jog.13996"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Yu A, Friedman S, Ananthakrishnan AN. Characteristics and long-term outcomes of pregnancy-onset inflammatory bowel disease: a case-control study. Inflamm Bowel Dis 27: 476-481, 2021.","DOI":"10.1093\/ibd\/izaa096"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/11\/64_4347-24\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T04:38:48Z","timestamp":1749271128000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/11\/64_4347-24\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,1]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4347-24","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,1]]},"article-number":"4347-24"}}