{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T04:01:07Z","timestamp":1749355267467,"version":"3.41.0"},"reference-count":10,"publisher":"Japanese Society of Internal Medicine","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2025,6,1]]},"DOI":"10.2169\/internalmedicine.4383-24","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T22:11:49Z","timestamp":1731017509000},"page":"1724-1727","source":"Crossref","is-referenced-by-count":0,"title":["Localized Unresectable Thymic Carcinoma Treated with Induction Chemotherapy with Lenvatinib before Radiotherapy"],"prefix":"10.2169","volume":"64","author":[{"given":"Shodai","family":"Fujimoto","sequence":"first","affiliation":[{"name":"Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoko","family":"Katsurada","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rie","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, Kobe University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeaki","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, Kobe University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Hazama","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatsugu","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoko","family":"Tachihara","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Gatta G, van der Zwan JM, Casali PG, et al.; The RARECARE working group. Rare cancers are not so rare: the rare cancer burden in Europe. Eur J Cancer 47: 2493-2511, 2011.","DOI":"10.1016\/j.ejca.2011.08.008"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. S\u00fcveg K, Putora PM, Joerger M, et al. Radiotherapy for thymic epithelial tumours: a review. Transl Lung Cancer Res 10: 2088-2100, 2021.","DOI":"10.21037\/tlcr-20-458"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Sato J, Satouchi M, Itoh S, et al. Lenvatinib in patients with advanced or metastatic thymic carcinoma (REMORA): a multicentre, phase 2 trial. Lancet Oncol 21: 843-850, 2020.","DOI":"10.1016\/S1470-2045(20)30162-5"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Shimura M, Miura K, Koizumi T, et al. Successful resection after first-line lenvatinib therapy in an advanced thymic carcinoma. Thorac Cancer 14: 1640-1643, 2023.","DOI":"10.1111\/1759-7714.14913"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Loehrer PJ Sr, Chen M, Kim K, et al. Cisplatin, doxorubicin, and cyclophosphamide plus thoracic radiation therapy for limited-stage unresectable thymoma: an intergroup trial. J Clin Oncol 15: 3093-3099, 1997.","DOI":"10.1200\/JCO.1997.15.9.3093"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Wang CL, Gao LT, Lv CX, Zhu Lei, Fang WT. Outcome of nonsurgical treatment for locally advanced thymic tumors. J Thorac Dis 8: 705-710, 2016.","DOI":"10.21037\/jtd.2016.01.79"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Fan XW, Yang Y, Wang HB, et al. Intensity modulated radiation therapy plus etoposide\/cisplatin for patients with limited advanced unresectable thymic epithelial tumors: a prospective phase 2 study. Int J Radiat Oncol Biol Phys 107: 98-105, 2020.","DOI":"10.1016\/j.ijrobp.2019.12.045"},{"key":"8","doi-asserted-by":"publisher","unstructured":"8. Niho S, Sato J, Satouchi M, et al. Long-term follow-up and exploratory analysis of lenvatinib in patients with metastatic or recurrent thymic carcinoma: results from the multicenter, phase 2 REMORA trial. Lung Cancer 191: 107557, 2024.","DOI":"10.1016\/j.lungcan.2024.107557"},{"key":"9","unstructured":"9. Camera S, Rimini M, Rossari F, et al. Safety and efficacy of lenvatinib in very old patients with unresectable hepatocellular carcinoma. Target Oncol 19: 29-39, 2024."},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kogure Y, Iwasawa S, Saka H, et al. Efficacy and safety of carboplatin with nab-paclitaxel versus docetaxel in older patients with squamous non-small-cell lung cancer (CAPITAL): a randomised, multicentre, open-label, phase 3 trial. Lancet Healthy Longev 2: e791-e800, 2021.","DOI":"10.1016\/S2666-7568(21)00255-5"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/11\/64_4383-24\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T04:39:06Z","timestamp":1749271146000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/11\/64_4383-24\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,1]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4383-24","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"type":"print","value":"0918-2918"},{"type":"electronic","value":"1349-7235"}],"subject":[],"published":{"date-parts":[[2025,6,1]]},"article-number":"4383-24"}}