{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,18]],"date-time":"2025-05-18T04:02:14Z","timestamp":1747540934794,"version":"3.40.5"},"reference-count":26,"publisher":"Japanese Society of Internal Medicine","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2025,5,15]]},"DOI":"10.2169\/internalmedicine.4424-24","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T22:11:29Z","timestamp":1729807889000},"page":"1569-1573","source":"Crossref","is-referenced-by-count":0,"title":["Management of Concurrent Immune Thrombocytopenia and Ulcerative Colitis: A Case Report and Literature Review"],"prefix":"10.2169","volume":"64","author":[{"given":"Masataka","family":"Hirai","sequence":"first","affiliation":[{"name":"Department of Hematology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minako","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Hematology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Hematology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Oka","sequence":"additional","affiliation":[{"name":"Department of Hematology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Murata","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koki","family":"Moriyoshi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kawabata","sequence":"additional","affiliation":[{"name":"Department of Hematology, NHO Kyoto Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. Rogler G, Singh A, Kavanaugh A, Rubin DT. Extraintestinal manifestations of inflammatory bowel disease: current concepts, treatment, and implications for disease management. Gastroenterology 161: 1118-1132, 2021.","DOI":"10.1053\/j.gastro.2021.07.042"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Mahajna H, Verstockt B, Bergemalm D, et al. Idiopathic Thrombocytopenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series. J Crohns Colitis 17: 722-777, 2023.","DOI":"10.1093\/ecco-jcc\/jjac179"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Raine T, Bonovas S, Burisch J, et al. ECCO guidelines on therapeutics in ulcerative colitis: medical treatment. J Crohns Colitis 16: 2-17, 2022.","DOI":"10.1093\/ecco-jcc\/jjab178"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Neunert C, Terrell DR, Arnold DM, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv 3: 3829-3866, 2019.","DOI":"10.1182\/bloodadvances.2019000966"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Suzuki K, Aizawa M, Tamazawa K, et al. Relapse of ulcerative colitis with immune thrombocytopenia and pyoderma gangrenosum subsequent to receiving COVID-19 vaccination. Intern Med 63: 665-669, 2024.","DOI":"10.2169\/internalmedicine.2969-23"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Subki AH, Bokhary MI, Alandijani SA, et al. Resolved hypereosinophilic syndrome and immune thrombocytopenic purpura in ulcerative colitis patients post colectomy: a case series and literature review. J Inflamm Res 15: 6373-6380, 2022.","DOI":"10.2147\/JIR.S365094"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Singh AK, Sasani A, Dhamor D, et al. Surgical management of medical refractory acute severe ulcerative colitis in immune thrombocytopenic purpura: killing two birds with one stone. Inflamm Bowel Dis 28: e90-e91, 2022.","DOI":"10.1093\/ibd\/izab324"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. de Medeiros Dutra R, Almeida LR, Sinkos C, et al. Immune thrombocytopenic purpura as an extraintestinal manifestation in a patient with ulcerative colitis. Case Rep Gastroenterol 16: 140-147, 2022.","DOI":"10.1159\/000522379"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Abdelmahmuod EA, Ali E, Ahmed MA, Yassin MA. Eltrombopag and its beneficial role in management of ulcerative Colitis associated with ITP as an upfront therapy case report. Clin Case Rep 9: 1416-1419, 2021.","DOI":"10.1002\/ccr3.3783"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Iwasa T, Nakamura K, Ihara E, Aso A, Ito T. The effective treatment with cyclosporine of a ulcerative colitis patient with concurrent idiopathic thrombocytopenic purpura who subsequently developed spontaneous pneumomediastinum. Intern Med 56: 1331-1337, 2017.","DOI":"10.2169\/internalmedicine.56.7909"},{"key":"11","unstructured":"11. Queliza K, Ihekweazu FD, Ali A, Kellermayer R. Inflammatory bowel disease and immune thrombocytopenic purpura: combined immune dysregulation in an adolescent. Ann Clin Lab Sci 47: 226-228, 2017."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Negoro A, Takano T, Tajiri H, Nezu R, Kawamura N, Brooks S. A role of colectomy in immune thrombocytopenic purpura associated with ulcerative colitis: a case report and a review of the literature. Int J Colorectal Dis 29: 1179-1180, 2014.","DOI":"10.1007\/s00384-014-1903-1"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Chandra S, Finn S, Obah E. Immune thrombocytopenic purpura in ulcerative colitis: a case report and systematic review. J Community Hosp Intern Med Perspect 4: 2014.","DOI":"10.3402\/jchimp.v4.23386"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Funato M, Fukao T, Sasai H, et al. Successful treatment of pediatric immune thrombocytopenic purpura associated with ulcerative colitis. Pediatr Int 53: 771-773, 2011.","DOI":"10.1111\/j.1442-200X.2010.03308.x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Mares WG, Gerver J, Masclee AA, Pierik M. Anti-TNF treatment of ulcerative colitis associated with idiopathic thrombocytopenic purpura. Inflamm Bowel Dis 17: 864-865, 2011.","DOI":"10.1002\/ibd.21327"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Hisada T, Miyamae Y, Mizuide M, et al. Acute thrombocytopenia associated with preexisting ulcerative colitis successfully treated with colectomy. Intern Med 45: 87-91, 2006.","DOI":"10.2169\/internalmedicine.45.1465"},{"key":"17","unstructured":"17. Varderili E, Sari\u00e7am T, Aslan V, G\u00fclba\u015f Z. Resolution of immune thrombocytopenic purpura after colectomy for ulcerative colitis. Turk J Gastroenterol 14: 270-272, 2003."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Mizuta Y, Isomoto H, Kadokawa Y, et al. Immune thrombocytopenic purpura in patients with ulcerative colitis. J Gastroenterol 38: 884-890, 2003.","DOI":"10.1007\/s00535-002-1166-4"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Higuchi LM, Joffe S, Neufeld EJ, et al. Inflammatory bowel disease associated with immune thrombocytopenic purpura in children. J Pediatr Gastroenterol Nutr 33: 582-587, 2001.","DOI":"10.1002\/j.1536-4801.2001.tb07539.x"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Miner RJ, Skoog SM. Immune thrombocytopenic purpura, profuse diarrhea, and new onset ulcerative colitis: a dramatic response to splenectomy. J Clin Gastroenterol 32: 276-277, 2001.","DOI":"10.1097\/00004836-200103000-00028"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Kodaira M, Hanai H, Kajimura M, et al. Further evidence that exacerbation of ulcerative colitis causes the onset of immune thrombocytopenia: a clinical case. Am J Gastroenterol 94: 1408-1410, 1999.","DOI":"10.1111\/j.1572-0241.1999.01098.x"},{"key":"22","unstructured":"22. Zlatanic J, Korelitz BI, Wisch N, et al. Inflammatory bowel disease and immune thrombocytopenic purpura: is there a correlation? Am J Gastroenterol 92: 2285-2288, 1997."},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. McCaulley ME. Immune thrombocytopenia and ulcerative colitis: response to nonoperative therapy. J Clin Gastroenterol 23: 242-243, 1996.","DOI":"10.1097\/00004836-199610000-00022"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Jinbo T, Tamura J, Shinohara M, et al. Possible causal association between ulcerative colitis and idiopathic thrombocytopenic purpura. Clin Rheumatol 11: 408-409, 1992.","DOI":"10.1007\/BF02207205"},{"key":"25","unstructured":"25. Bauer WM, Litchtin A, Lashner BA. Can colectomy cure immune thrombocytopenic purpura in a patient with ulcerative colitis? Dig Dis Sci 44: 2330-2333, 1999."},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Takeuchi H, Okamoto A. <i>Helicobacter pylori<\/i> infection and chronic immune thrombocytopenia. J Clin Med 11: 4822, 2022.","DOI":"10.3390\/jcm11164822"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/10\/64_4424-24\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T03:26:22Z","timestamp":1747452382000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/10\/64_4424-24\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,15]]},"references-count":26,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4424-24","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"type":"print","value":"0918-2918"},{"type":"electronic","value":"1349-7235"}],"subject":[],"published":{"date-parts":[[2025,5,15]]},"article-number":"4424-24"}}