{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T19:23:27Z","timestamp":1784229807530,"version":"3.55.0"},"reference-count":33,"publisher":"Japanese Society of Internal Medicine","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2020,8,1]]},"DOI":"10.2169\/internalmedicine.4465-20","type":"journal-article","created":{"date-parts":[[2020,5,25]],"date-time":"2020-05-25T22:04:45Z","timestamp":1590444285000},"page":"1803-1809","source":"Crossref","is-referenced-by-count":5,"title":["Use of a Low-carbohydrate Enteral Nutrition Formula with Effective Inhibition of Hypoglycemia and Post-infusion Hyperglycemia in Non-diabetic Patients Fed via a Jejunostomy Tube"],"prefix":"10.2169","volume":"59","author":[{"given":"Shinji","family":"Nishiwaki","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Nishimino Kosei Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Tokai University School of Medicine, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Kurobe","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nishimino Kosei Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nishimino Kosei Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahide","family":"Iwashita","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nishimino Kosei Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroo","family":"Hatakeyama","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nishimino Kosei Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nishimino Kosei Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruo","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nishimino Kosei Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Chowdhury MA, Batey R. Complications and outcome of percutaneous endoscopic gastrostomy in different patient groups. J Gastroenterol Hepatol 11: 835-839, 1996.","DOI":"10.1111\/j.1440-1746.1996.tb00089.x"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Coben RM, Weintraub A, DiMarino AJ, Cohen S. Gastroesophageal reflux during gastrostomy feeding. Gastroenterol 106: 13-18, 1994.","DOI":"10.1016\/S0016-5085(94)93969-1"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Nishiwaki S, Araki H, Goto N, et al. Clinical analysis of gastroesophageal reflux after PEG. Gastrointest Endosc 64: 890-896, 2006.","DOI":"10.1016\/j.gie.2006.06.086"},{"key":"4","unstructured":"4. Ponsky JL, Aszodi A. Percutaneous endoscopic jejunostomy. Am J Gastroenterol 79: 113-116, 1984."},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Shike M, Schroy P, Ritchie MA, Lightdale CJ, Morse R. Percutanous endoscopic jejunostomy in cancer patients with previous gastric resection. Gastrointest Endosc 33: 372-374, 1987.","DOI":"10.1016\/S0016-5107(87)71642-3"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Shike M, Wallach C, Lacier H. Direct percutaneous endoscopic jejunostomies. Gastrointest Endosc 37: 62-65, 1991.","DOI":"10.1016\/S0016-5107(91)70625-1"},{"key":"7","unstructured":"7. Mathus-Vliegen LM, Koning H. Percutaneous endoscopic gastrostomy and gastrojejunostomy: a critical reappraisal of patient selection, tube function and the feasibility of nutritional support during extended follow-up. Gastrointest Endosc 50: 746-754, 1999."},{"key":"8","unstructured":"8. Ryan JA Jr, Page CP. Intrajejunal feeding: development and current status. JPEN J Parenter Enteral Nutr 8: 187-198, 1984."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Schrezenmeir J. Rationale for specialized nutrition support for hyperglycemic patients. Clin Nutr 17 (Suppl 2): 26-34, 1998.","DOI":"10.1016\/S0261-5614(98)80015-0"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Mori Y, Ohta T, Yokoyama J, Utsunomiya K. Effects of low-carbohydrate\/high-monounsaturated fatty acid liquid diets on diurnal glucose variability and insulin dose in type 2 diabetes patients on tube feeding who require insulin therapy. Diabetes Technol Ther 15: 762-767, 2013.","DOI":"10.1089\/dia.2013.0066"},{"key":"11","unstructured":"11. Tapia J, Murguia R, Garcia G, de los Monteros PE, O\u00f1ate E. Jejunostomy: techniques, indications, and complications. World J Surg 23: 596-602, 1999."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Fang JC. Minimizing endoscopic complications in enteral access. Gastrointest Endosc Clin N Am 17: 179-196, 2007.","DOI":"10.1016\/j.giec.2006.10.003"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Custer MD, Butt HR, Waugh JM. The so-called dumping syndrome after subtotal gastrectomy. Ann Surg 123: 410-418, 1946.","DOI":"10.1097\/00000658-194603000-00007"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Smith-Choban P, Max MH. Feeding jejunostomy: a small bowel stress test? Am J Surg 155: 112-117, 1988.","DOI":"10.1016\/S0002-9610(88)80267-8"},{"key":"15","unstructured":"15. Lawrence W Jr. Nutritional consequences of surgical resection of the gastrointestinal tract for cancer. Cancer Res 37: 2379-2386, 1977."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Halverson JD. Vitamin and mineral deficiencies following obesity surgery. Gastroenterol Clin North Am 16: 307-315, 1987.","DOI":"10.1016\/S0889-8553(21)00294-6"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Nishiwaki S, Iwashita M, Goto N, et al. Predominant copper deficiency during prolonged enteral nutrition through a jejunostomy tube compared to that through a gastrostomy tube. Clin Nutr 30: 585-589, 2011.","DOI":"10.1016\/j.clnu.2011.04.008"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Breuer RI, Moses H 3rd, Hagen TC, Zuckerman L. Gastric operations and glucose homeostasis. Gastroenterology 62: 1109-1119, 1972.","DOI":"10.1016\/S0016-5085(72)80078-7"},{"key":"19","unstructured":"19. Fiorillo C, Rosa F, Quero G, Menghi R, Doglietto GB, Alfieri S. Postoperative hyperglycemia in nondiabetic patients after gastric surgery for cancer: perioperative outcomes. Gastric Cancer 20: 536-542, 2017."},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Breitman I, Isbell JM, Saliba J, et al. Effects of proximal gut bypass on glucose tolerance and insulin sensitivity in humans. Diabetes Care 36: e57, 2013.","DOI":"10.2337\/dc12-1722"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Jain A, Gupta AK, Jat KR, Kabra SK. Late dumping syndrome in an infant on feeding jejunostomy. BMJ Case Rep 12: e228471, 2019.","DOI":"10.1136\/bcr-2018-228471"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Service GJ, Thompson GB, Service FJ, Andrews JC, Collazo-Clavell ML, Lloyd RV. Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery. N Engl J Med 353: 249-254, 2005.","DOI":"10.1056\/NEJMoa043690"},{"key":"23","unstructured":"23. Hirakawa Y, Arima H, Zoungas S, et al. Impact of visit-to-visit glycemic variability on the risks of macrovascular and microvascular events and all-cause mortality in type 2 diabetes: the ADVANCE trial. Diabetes Care 37: 2359-2365, 2014."},{"key":"24","unstructured":"24. Ritz P, Vaurs C, Barigou M, Hanaire H. Hypoglycaemia after gastric bypass: mechanisms and treatment. Diabetes Obes Metab 18: 217-223, 2016."},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Borges VC. Specialized enteral formulae for diabetic patients. Nutrition 19: 196-198, 2003.","DOI":"10.1016\/S0899-9007(02)00848-1"},{"key":"26","unstructured":"26. Le\u00f3n-Sanz M, Garc\u00eda-Luna PP, Sanz-Par\u00eds A, et al.; Abbott SPAI-97-004 Study Cooperative Group. Glycemic and lipid control in hospitalized type 2 diabetic patients: evaluation of 2 enteral nutrition formulas (low carbohydrate-high monounsaturated fat vs. high carbohydrate). J Parenter Enteral Nutr 29: 21-29, 2005."},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Wang WQ, Zhang YF, Zhou DJ, et al. Open-label, randomized, multiple-center, parallel study comparing glycemic responses and safety profiles of Glucerna versus Fresubin in subjects of type 2 diabetes mellitus. Endocrine 33: 45-52, 2008.","DOI":"10.1007\/s12020-008-9059-9"},{"key":"28","unstructured":"28. Pohl M, Mayr P, Mertl-Roetzer M, et al. Glycaemic control in type II diabetic tube-fed patients with a new enteral formula low in carbohydrates and high in monounsaturated fatty acids: a randomised controlled trial. Eur J Clin Nutr 59: 1221-1232, 2005."},{"key":"29","unstructured":"29. Kellogg TA, Bantle JP, Leslie DB, et al. Postgastric bypass hyperinsulinemic hypoglycemia syndrome: characterization and response to a modified diet. Surg Obes Relat Dis 4: 492-499, 2008."},{"key":"30","unstructured":"30. Becker DJ, Sinclair J, Castell DO, Wu WC. A comparison of high and low fat meals on postprandial esophageal acid exposure. Am J Gastroenterol 84: 782-786, 1989."},{"key":"31","unstructured":"31. Stacher G, Bergmann H, Gaupmann G, et al. Fat preload delays gastric emptying: reversal by cisapride. Br J Clin Pharmacol 30: 839-845, 1990."},{"key":"32","unstructured":"32. Adachi S, Oura G, Kitazawa T, et al. A case of the patient with jejunal tube through the percutaneous endoscopic gastrostomy who vomited gastric juice frequently after the high fat enteral formula. Nihon Shokakibyo Gakkai Zasshi 101: 36-40, 2004 (in Japanese, Abstract in English)."},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Mottalib A, Mohd-Yusof BN, Shehabeldin M, Pober DM, Mitri J, Hamdy O. Impact of diabetes-specific nutritional formulas versus oatmeal on postprandial glucose, insulin, GLP-1 and postprandial lipidemia. Nutrients 8: E443, 2016.","DOI":"10.3390\/nu8070443"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/59\/15\/59_4465-20\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T21:22:11Z","timestamp":1666646531000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/59\/15\/59_4465-20\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,1]]},"references-count":33,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4465-20","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,1]]}}}