{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:11:50Z","timestamp":1782889910703,"version":"3.54.5"},"reference-count":30,"publisher":"Japanese Society of Internal Medicine","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2025,6,15]]},"DOI":"10.2169\/internalmedicine.4546-24","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T22:15:47Z","timestamp":1732745747000},"page":"1808-1819","source":"Crossref","is-referenced-by-count":2,"title":["Deterioration of the Defecation Status after Hospitalization in Patients with Type 2 Diabetes Is Associated with Albuminuria Rather Than Diabetic Neuropathy"],"prefix":"10.2169","volume":"64","author":[{"given":"Hiroyuki","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuho","family":"Shibuya","sequence":"additional","affiliation":[{"name":"Department of Nursing, Edogawa Medicare Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riko","family":"Iwami","sequence":"additional","affiliation":[{"name":"Department of Nursing, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitomi","family":"Ina","sequence":"additional","affiliation":[{"name":"Department of Nursing, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayo","family":"Okawa","sequence":"additional","affiliation":[{"name":"Department of Nursing, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiaki","family":"I","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzuko","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Antoku","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiko","family":"Togane","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","unstructured":"1. Ministry of Health, Labour and Welfare. Summary report of Comprehensive Survey of Living Conditions 2022 [Internet]. [cited 2024 Aug 11]. Available from: https:\/\/www.mhlw.go.jp\/english\/database\/db-hss\/dl\/report_gaikyo_2022.pdf"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Kubota Y, Iso H, Tamakoshi A. Bowel movement frequency, laxative use, and mortality from coronary heart disease and stroke among Japanese men and women: the Japan Collaborative Cohort (JACC) Study. J Epidemiol 26: 242-248, 2016.","DOI":"10.2188\/jea.JE20150123"},{"key":"3","doi-asserted-by":"publisher","unstructured":"3. Honkura K, Tomata Y, Sugiyama K, et al. Defecation frequency and cardiovascular disease mortality in Japan: the Ohsaki cohort study. Atherosclerosis 246: 251-256, 2016.","DOI":"10.1016\/j.atherosclerosis.2016.01.007"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Ma W, Li Y, Heianza Y, et al. Associations of bowel movement frequency with risk of cardiovascular disease and mortality among US women. Sci Rep 6: 33005, 2016.","DOI":"10.1038\/srep33005"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5. Sumida K, Molnar MZ, Potukuchi PK, et al. Constipation and risk of death and cardiovascular events. Atherosclerosis 281: 114-120, 2019.","DOI":"10.1016\/j.atherosclerosis.2018.12.021"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6. Yang S, Yu C, Guo Y, et al; the China Kadoorie Biobank Collaborative Group. Bowel movement frequency and risks of major vascular and non-vascular diseases: a population-based cohort study among Chinese adults. BMJ Open 10: e031028, 2020.","DOI":"10.1136\/bmjopen-2019-031028"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Sumida K, Molnar MZ, Potukuchi PK, et al. Constipation and incident CKD. J Am Soc Nephrol 28: 1248-1258, 2017.","DOI":"10.1681\/ASN.2016060656"},{"key":"8","unstructured":"8. Research Society for the Diagnosis and Treatment of Chronic Constipation\/Affiliated to the Japanese Society of Gastroenterology. Evidence-based Clinical Practice Guidelines for Chronic Constipation 2017. Nankodo, Tokyo, 2017 (in Japanese)."},{"key":"9","unstructured":"9. The Japanese Gastroenterological Association. Evidence-based Clinical Practice Guidelines for Chronic Constipatin 2023. Nankodo, Tokyo, 2023 (in Japanese)."},{"key":"10","doi-asserted-by":"publisher","unstructured":"10. Locke GR 3rd, Pemberton JH, Phillips SF. AGA technical review on constipation. Gastroenterology 119: 1766-1778, 2000.","DOI":"10.1053\/gast.2000.20392"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Ihana-Sugiyama N, Nagata N, Yamamoto-Honda R, et al. Constipation, hard stools, fecal urgency, and incomplete evacuation, but not diarrhea is associated with diabetes and its related factors. World J Gastroenterol 22: 3252-3260, 2016.","DOI":"10.3748\/wjg.v22.i11.3252"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Bytzer P, Talley NJ, Leemon M, Young LJ, Jones MP, Horowitz M. Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults. Arch Intern Med 161: 1989-1996, 2001.","DOI":"10.1001\/archinte.161.16.1989"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Ito H, Ito K, Tanaka M, et al. Constipation is a frequent problem associated with vascular complications in patients with type 2 diabetes: a cross-sectional study. Intern Med 61: 1309-1317, 2022.","DOI":"10.2169\/internalmedicine.7676-21"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Noiesen E, Trosborg I, Bager L, Herning M, Lyngby C, Konradsen H. Constipation - prevalence and incidence among medical patients acutely admitted to hospital with a medical condition. J Clin Nurs 23: 2295-2302, 2014.","DOI":"10.1111\/jocn.12511"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Al Nou&apos;mani J, Al Alawi AM, Al-Maqbali JS, Al Abri N, Al Sabbri M. Prevalence, recognition, and risk factors of constipation among medically hospitalized patients: a cohort prospective study. Medicina (Kaunas) 59: 1347, 2023.","DOI":"10.3390\/medicina59071347"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. O&apos;Donnell LJ, Virjee J, Heaton KW. Detection of pseudodiarrhoea by simple clinical assessment of intestinal transit rate. BMJ 300: 439-440, 1990.","DOI":"10.1136\/bmj.300.6722.439"},{"key":"17","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1053\/j.gastro.2016.02.031","volume":"150","author":"F Mearin","year":"2016","unstructured":"17. Mearin F, Lacy BE, Chang L, et al. Bowel disorders. Gastroenterology 150: 1393-1407, 2016.","journal-title":"Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Examination Committee of Criteria for &apos;Obesity Disease&apos; in Japan, Japan Society for the Study of Obesity. New criteria for &apos;obesity disease&apos; in Japan. Circ J 66: 987-992, 2002.","DOI":"10.1253\/circj.66.987"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Matsuo S, Imai E, Horio M, et al; Collaborators developing the Japanese equation for estimated GFR. Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 53: 982-992, 2009.","DOI":"10.1053\/j.ajkd.2008.12.034"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Yasuda H, Sanada M, Kitada K, et al. Rationale and usefulness of newly devised abbreviated diagnostic criteria and staging for diabetic polyneuropathy. Diabetes Res Clin Pract 77 (Suppl 1): S178-S183, 2007.","DOI":"10.1016\/j.diabres.2007.01.053"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Iovino P, Chiarioni G, Bilancio G, et al. New onset of constipation during long-term physical inactivity: a proof-of-concept study on the immobility-induced bowel changes. PLoS One 8: e72608, 2013.","DOI":"10.1371\/journal.pone.0072608"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Yamada E, Namiki Y, Takano Y, et al. Clinical factors associated with the symptoms of constipation in patients with diabetes mellitus: a multicenter study. J Gastroenterol Hepatol 33: 863-868, 2018.","DOI":"10.1111\/jgh.14022"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Bellizzi V, Scalfi L, Terracciano V, et al. Early changes in bioelectrical estimates of body composition in chronic kidney disease. J Am Soc Nephrol 17: 1481-1487, 2006.","DOI":"10.1681\/ASN.2005070756"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Basile C, Della-Morte D, Cacciatore F, et al. Phase angle as bioelectrical marker to identify elderly patients at risk of sarcopenia. Exp Gerontol 58: 43-46, 2014.","DOI":"10.1016\/j.exger.2014.07.009"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Yamada M, Kimura Y, Ishiyama D, et al. Phase angle is a useful indicator for muscle function in older adults. J Nutr Health Aging 23: 251-255, 2019.","DOI":"10.1007\/s12603-018-1151-0"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Muramae N, Matsuda T, Inagaki S, et al. Determinants of phase angle in Japanese patients with diabetes. Diabetol Int 14: 339-343, 2023.","DOI":"10.1007\/s13340-023-00633-1"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Oyanagi T, Sada Y, Sasaki Y, Sone M, Tanaka Y. Associations of phase angle obtained by bioelectrical impedance analysis with muscle mass and strength in Japanese patients with type 2 diabetes. Endocr J 70: 925-932, 2023.","DOI":"10.1507\/endocrj.EJ23-0022"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Choi HN, Kim KA, Kim YS, Yim JE. Independent association of phase angle with fasting blood glucose and hemoglobin A1c in Korean type 2 diabetes patients. Clin Nutr Res 9: 205-212, 2020.","DOI":"10.7762\/cnr.2020.9.3.205"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Chen LK, Woo J, Assantachai P, et al. Asian Working Group for Sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir 21: 300-307.e2, 2020.","DOI":"10.1016\/j.jamda.2019.12.012"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Konta T, Hao Z, Abiko H, et al. Prevalence and risk factor analysis of microalbuminuria in Japanese general population: the Takahata study. Kidney Int 70: 751-756, 2006.","DOI":"10.1038\/sj.ki.5001504"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/12\/64_4546-24\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T04:00:25Z","timestamp":1750478425000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/12\/64_4546-24\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,15]]},"references-count":30,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4546-24","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,15]]},"article-number":"4546-24"}}