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Clinical and molecular characterization of hereditary spastic paraplegias: a next-generation sequencing panel approach. J Neurol Sci 383: 18-25, 2017."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Gillespie MK, Humphreys P, McMillan HJ, Boycott KM. Association of early-onset spasticity and risk for cognitive impairment with Mutations at amino acid 499 in SPAST. J Child Neurol 33: 329-332, 2018.","DOI":"10.1177\/0883073818756680"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Meszarosova AU, Putzova M, Cermakova M, et al. SPAST mutation spectrum and familial occurrence among Czech patients with pure hereditary spastic paraplegia. J Hum Genet 61: 845-850, 2016.","DOI":"10.1038\/jhg.2016.73"},{"key":"8","doi-asserted-by":"publisher","unstructured":"8. Depienne C, Fedirko E, Faucheux JM, et al. A de novo SPAST mutation leading to somatic mosaicism is associated with a later age at onset in HSP. 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Spreadsheets of a conventional application software for calculation of plausibility of paternity: application to parentage testing with highly polymorphic markers in deceased party. Nihon Hoigaku Zasshi 51: 196-204, 1997 (in Japanese, Abstract in English)."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Parodi L, Fenu S, Barbier M, et al. Spastic paraplegia due to SPAST mutations is modified by the underlying mutation and sex. Brain 141: 3331-3342, 2018.","DOI":"10.1093\/brain\/awy285"},{"key":"17","unstructured":"17. Namekawa M, Takiyama Y, Sakoe K, et al. A large Japanese SPG4 family with a novel insertion mutation of the SPG4 gene: a clinical and genetic study. J Neurol Sci 185: 63-68, 2001."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Meijer IA, Dupr\u00e9 N, Brais B, et al. SPG4 founder effect in French Canadians with hereditary spastic paraplegia. 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