{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T09:59:14Z","timestamp":1777111154609,"version":"3.51.4"},"reference-count":11,"publisher":"Japanese Society of Internal Medicine","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2025,7,15]]},"DOI":"10.2169\/internalmedicine.4720-24","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T17:13:47Z","timestamp":1734542027000},"page":"2160-2164","source":"Crossref","is-referenced-by-count":2,"title":["Acute Liver Failure Caused by Isoniazid during Preventive Treatment for Latent Tuberculosis: A Rare Autopsy Case Report"],"prefix":"10.2169","volume":"64","author":[{"given":"Yuka","family":"Yamazaki","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Tominaga","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Arisaka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayuko","family":"Tagaya","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Kojimahara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Ohnishi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Majima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Yamamiya","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Iijima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoya","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Niho","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhei","family":"Noda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Irisawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University School of Medicine, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Comstock GW. Prevention tuberculosis among tuberculin reactors: maximizing benefits, minimizing risks. JAMA 256: 2729-2730, 1986.","DOI":"10.1001\/jama.1986.03380190099036"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Rose DN, Schechter CB, Silver AL. The age threshold for isoniazid chemoprophylaxis: a decision analysis for low-risk tuberculin reactors. JAMA 256: 2709-2713, 1986.","DOI":"10.1001\/jama.1986.03380190079029"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. American Thoracic Society. Targeted tuberculin testing and treatment of latent tuberculosis infection. Am J Respir Crit Care Med 161: S221-S247, 2000.","DOI":"10.1164\/ajrccm.161.supplement_3.ats600"},{"key":"4","unstructured":"4. Sotsuka T, Sasaki Y, Hirai S, Yamagishi F, Ueno K. Association of isoniazid- metabolizing enzyme genotypes and isoniazid-induced hepatotoxicity in tuberculosis patients. In Vivo 25: 803-812, 2011."},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Sarich TC, Adams SP, Petricca G, Wright JM. Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor. J Pharmacol Exp Ther 289: 695-702, 1999.","DOI":"10.1016\/S0022-3565(24)38190-X"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Miyazawa S, Matsuoka S, Hamana S, et al. Isoniazid-induced acute liver failure during preventive therapy for latent tuberculosis infection. Intern Med 54: 591-595, 2015.","DOI":"10.2169\/internalmedicine.54.3669"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Khan FY, Rasoul F. Rifampicin-isoniazid induced fatal fulminant hepatitis during treatment of latent tuberculosis: a case report and literature review. Indian J Crit Care Med 14: 97-100, 2010.","DOI":"10.4103\/0972-5229.68226"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Saukkonen JJ, Cohn DL, Jasmer RM, et al.; ATS (American Thoracic Society) Hepatotoxicity of Antituberculosis Therapy Subcommittee. An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med 174: 935-952, 2006.","DOI":"10.1164\/rccm.200510-1666ST"},{"key":"9","unstructured":"9. Kopanoff DE, Snider DE Jr, Caras GJ. Isoniazid-related hepatitis: a U.S. Public Health Service cooperative surveillance study. Am Rev Respir Dis 117: 991-1001, 1978."},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Sato S, Suzuki K, Takikawa Y, Endo R, Omata M. Japanese National Study Group of Fulminant Hepatitis. Clinical epidemiology of fulminant hepatitis in Japan before the substantial introduction of liver transplantation: an analysis of 1309 cases in a 15-year national survey. Hepatol Res 30: 155-161, 2004.","DOI":"10.1016\/j.hepres.2004.08.003"},{"key":"11","unstructured":"11. Westerhoff M, Lamps LW, Kakar S. Diagnostic Pathology: Hepatobiliary & Pancreas. Third ed. Amirsys, Salt Lake City, 2022: 174-181."}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/14\/64_4720-24\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T03:50:41Z","timestamp":1752897041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/14\/64_4720-24\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,15]]},"references-count":11,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4720-24","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,15]]},"article-number":"4720-24"}}