{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T16:42:40Z","timestamp":1755794560018,"version":"3.44.0"},"reference-count":26,"publisher":"Japanese Society of Internal Medicine","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2025,8,15]]},"DOI":"10.2169\/internalmedicine.4907-24","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T17:12:33Z","timestamp":1739812353000},"page":"2452-2457","source":"Crossref","is-referenced-by-count":0,"title":["&lt;i&gt;Helicobacter pylori&lt;\/i&gt;-positive Colorectal MALT Lymphoma with Repeated Metachronous Recurrence after a Complete Response to Eradication Therapy and Regression after a Watch-and-wait Strategy"],"prefix":"10.2169","volume":"64","author":[{"given":"Daisuke","family":"Shimizu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidehiko","family":"Takigawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Kitadai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misa","family":"Ariyoshi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Hiyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Urabe","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshio","family":"Kuwai","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Endoscopy and Medicine, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"Oka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hiroshima University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. Isaacson P, Wright DH. Malignant lymphoma of mucosa-associated lymphoid tissue. A distinctive type of B-cell lymphoma. Cancer 52: 1410-1416, 1983.","DOI":"10.1002\/1097-0142(19831015)52:8<1410::AID-CNCR2820520813>3.0.CO;2-3"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Koch P, del Valle F, Berdel WE, et al. Primary gastrointestinal non-Hodgkin&apos;s lymphoma: I. anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GIT NHL 01\/92. J Clin Oncol 19: 3861-3873, 2001.","DOI":"10.1200\/JCO.2001.19.18.3861"},{"key":"3","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1136\/gutjnl-2011-300495","volume":"61","author":"S Nakamura","year":"2012","unstructured":"3. Nakamura S, Sugiyama T, Matsumoto T, et al. Long-term clinical outcome of gastric MALT lymphoma after eradication of <i>Helicobacter pylori<\/i>: a multicentre cohort follow-up study of 420 patients in Japan. Gut 61: 507-513, 2012.","journal-title":"Gut","ISSN":"https:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4. Takigawa H, Yuge R, Masaki S, et al. Involvement of non-<i>Helicobacter pylori<\/i> helicobacter infections in <i>Helicobacter pylori<\/i>-negative gastric MALT lymphoma pathogenesis and efficacy of eradication therapy. Gastric Cancer 24: 937-945, 2021.","DOI":"10.1007\/s10120-021-01172-x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Ureshino H, Ito Y. Treatment choice for primary rectal MALT lymphoma. QJM 112: 637-638, 2019.","DOI":"10.1093\/qjmed\/hcy206"},{"key":"6","unstructured":"6. [NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines<sup>\u00ae<\/sup>). B-cell lymphomas, Version 2.2024.] [Internet]. Available from: https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/b-cell.pdf"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7. Kimura K, Takemoto T. An endoscopic recognition of the atrophic border and its significance in chronic gastritis. Endoscopy 1: 87-97, 1969.","DOI":"10.1055\/s-0028-1098086"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Won JH, Kim SM, Kim JW, Park JH, Kim JY. Clinical features, treatment and outcomes of colorectal mucosa-associated lymphoid tissue (MALT) lymphoma: literature reviews published in English between 1993 and 2017. Cancer Manag Res 11: 8577-8587, 2019.","DOI":"10.2147\/CMAR.S214197"},{"key":"9","unstructured":"9. Sagawa T, Tsuji Y, Takayanagi N, et al. Metachronous and multiple mucosa-associated lymphoid tissue lymphomas of the cecum and rectum. Nihon Shokaki Naishikyo Gakkai Zasshi (Gastroenterol Endosc) 45: 2111-2117, 2003."},{"key":"10","doi-asserted-by":"publisher","unstructured":"10. Matsumoto T, Iida M, Shimizu M. Regression of mucosa-associated lymphoid-tissue lymphoma of rectum after eradication of <i>Helicobacter pylori<\/i>. Lancet 350: 115-116, 1997.","DOI":"10.1016\/S0140-6736(05)61818-1"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kelley SR. Mucosa-associated lymphoid tissue (MALT) variant of primary rectal lymphoma: a review of the English literature. Int J Colorectal Dis 32: 295-304, 2017.","DOI":"10.1007\/s00384-016-2734-z"},{"key":"12","unstructured":"12. Nomura E, Uchimi K, Abue M, et al. [Regression of MALT lymphoma of the rectum after <i>Helicobacter pylori<\/i> eradication therapy in a patient negative for <i>Helicobacter pylori<\/i>]. Nihon Shokakibyo Gakkai Zasshi (J Jpn Soc Gastroenterol) 107: 1466-1473, 2010."},{"key":"13","doi-asserted-by":"publisher","unstructured":"13. Inoue F, Chiba T. Regression of MALT lymphoma of the rectum after anti-<i>H. pylori<\/i> therapy in a patient negative for <i>H. pylori<\/i>. Gastroenterology 117: 514-515, 1999.","DOI":"10.1053\/gast.1999.0029900514b"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Ishikawa E, Nakamura M, Satou A, Shimada K, Nakamura S. Mucosa-associated lymphoid tissue (MALT) lymphoma in the gastrointestinal tract in the modern era. Cancers (Basel) 14: 2022.","DOI":"10.3390\/cancers14020446"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15. Raderer M, Streubel B, Wohrer S, Hafner M, Chott A. Successful antibiotic treatment of <i>Helicobacter pylori<\/i> negative gastric mucosa associated lymphoid tissue lymphomas. Gut 55: 616-618, 2006.","DOI":"10.1136\/gut.2005.083022"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Zucca E, Arcaini L, Buske C, et al. Marginal zone lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 31: 17-29, 2020.","DOI":"10.1016\/j.annonc.2019.10.010"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Takenaka R, Tomoda J, Sakata T, et al. Mucosa-associated lymphoid tissue lymphoma of the rectum that regressed spontaneously. J Gastroenterol Hepatol 15: 331-335, 2000.","DOI":"10.1046\/j.1440-1746.2000.02086.x"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Shigematsu A, Iida M, Lien GS, et al. Spontaneous regression of primary malignant lymphoma of the stomach in two nontreated Japanese. J Clin Gastroenterol 11: 511-517, 1989.","DOI":"10.1097\/00004836-198910000-00006"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Uohashi A, Imoto S, Matsui T, et al. Spontaneous regression of diffuse large-cell lymphoma associated with Hashimoto&apos;s thyroiditis. Am J Hematol 53: 201-202, 1996.","DOI":"10.1002\/(SICI)1096-8652(199611)53:3<201::AID-AJH10>3.0.CO;2-G"},{"key":"20","unstructured":"20. Troch M, Streubel B, Petkov V, Turetschek K, Chott A, Raderer M. Does MALT lymphoma of the lung require immediate treatment? An analysis of 11 untreated cases with long-term follow-up. Anticancer Res 27: 3633-3637, 2007."},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Abe R, Ogawa K, Maruyama Y, Nakamura N, Abe M. Spontaneous regression of diffuse large B-cell lymphoma harbouring Epstein-Barr virus: a case report and review of the literature. J Clin Exp Hematop 47: 23-26, 2007.","DOI":"10.3960\/jslrt.47.23"},{"key":"22","doi-asserted-by":"publisher","unstructured":"22. Grem JL, Hafez GR, Brandenburg JH, Carbone PP. Spontaneous remission in diffuse large cell lymphoma. Cancer 57: 2042-2044, 1986.","DOI":"10.1002\/1097-0142(19860515)57:10<2042::AID-CNCR2820571027>3.0.CO;2-#"},{"key":"23","doi-asserted-by":"publisher","unstructured":"23. Kumamoto M, Nakamine H, Hara T, et al. Spontaneous complete regression of high grade non-Hodgkin&apos;s lymphoma. Morphologic, immunohistochemical, and gene amplification analyses. Cancer 74: 3023-3028, 1994.","DOI":"10.1002\/1097-0142(19941201)74:11<3023::AID-CNCR2820741120>3.0.CO;2-Y"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Koga M, Kusukawa J, Hayabuchi N. Spontaneous regression of extranodal malignant lymphoma occurred in the gingiva. Oral Oncol 39: 323-324, 2003.","DOI":"10.1016\/S1368-8375(02)00122-7"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Raderer M, Streubel B, Woehrer S, et al. High relapse rate in patients with MALT lymphoma warrants lifelong follow-up. Clin Cancer Res 11: 3349-3352, 2005.","DOI":"10.1158\/1078-0432.CCR-04-2282"},{"key":"26","unstructured":"26. Chiyoda S, Morikawa T, Takahara O. [Temporary spontaneous remission in Ki-1 (CD30) lymphoma with gastric lesion]. Rinsho Ketsueki (Jpn J Clin Hematol) 32: 1463-1468, 1991."}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/16\/64_4907-24\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T03:43:23Z","timestamp":1755315803000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/16\/64_4907-24\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,15]]},"references-count":26,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4907-24","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"type":"print","value":"0918-2918"},{"type":"electronic","value":"1349-7235"}],"subject":[],"published":{"date-parts":[[2025,8,15]]},"article-number":"4907-24"}}