{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T10:44:22Z","timestamp":1751625862089},"reference-count":14,"publisher":"Japanese Society of Internal Medicine","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2021,1,1]]},"DOI":"10.2169\/internalmedicine.4957-20","type":"journal-article","created":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T22:05:38Z","timestamp":1598047538000},"page":"137-140","source":"Crossref","is-referenced-by-count":8,"title":["Anti-MuSK Positive Myasthenia Gravis with Anti-Lrp4 and Anti-titin Antibodies"],"prefix":"10.2169","volume":"60","author":[{"given":"Rika","family":"Yamashita","sequence":"first","affiliation":[{"name":"Department of Neurology, Osaka University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikito","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaka University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kousuke","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaka University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goichi","family":"Beck","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaka University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Kinoshita","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaka University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsusada","family":"Okuno","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaka University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Higuchi","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Nagasaki Kawatana Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Mochizuki","sequence":"additional","affiliation":[{"name":"Department of Neurology, Osaka University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Leite MI, Waters P, Vincent A. Diagnosic use of autoantibodies in myasthenia gravis. Autoimmunity 43: 371-379, 2010.","DOI":"10.3109\/08916930903541208"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Hoch W, Mcconville J, Helms S, Newsom-Davis J, Melms A, Vincent A. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat Med 7: 365-368, 2001.","DOI":"10.1038\/85520"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Higuchi O, Hamuro J, Motomura M, Yamanashi Y. Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis. Ann Neurol 69: 418-422, 2011.","DOI":"10.1002\/ana.22312"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Pevzner A, Schoser B, Peters K, et al. Anti-LRP4 autoantibodies in AChR- and MuSK-antibodynegative myasthenia gravis. J Neurol 259: 427-435, 2012.","DOI":"10.1007\/s00415-011-6194-7"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Zhang B, Tzartos JS, Belimezi M, et al. Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis. Arch Neurol 69: 445-451, 2012.","DOI":"10.1001\/archneurol.2011.2393"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Zisimopoulou P, Evangelakou P, Tzartos J, et al. A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis. J Autoimmun 52: 139-145, 2014.","DOI":"10.1016\/j.jaut.2013.12.004"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Cossins J, Belaya K, Zoltowska K, et al. The search for new antigenic targets in myasthenia gravis. Ann N Y Acad Sci 1275: 123-128, 2012.","DOI":"10.1111\/j.1749-6632.2012.06833.x"},{"key":"8","unstructured":"8. Suzuki S, Utsugisawa K, Nagane Y, Suzuki N. Three types of striational antibodies in myasthenia gravis. Autoimmune Dis. Forthcoming."},{"key":"9","doi-asserted-by":"publisher","unstructured":"9. Kim N, Stiegler AL, Cameron TO, et al. Lrp4 is a receptor for agrin and forms a complex with MuSK. Cell 135: 334-342, 2008.","DOI":"10.1016\/j.cell.2008.10.002"},{"key":"10","doi-asserted-by":"publisher","unstructured":"10. Zhang B, Luo S, Wang Q, Suzuki T, Xiong WC, Mei L. LRP4 serves as a coreceptor of agrin. Neuron 60: 285-297, 2008.","DOI":"10.1016\/j.neuron.2008.10.006"},{"key":"11","unstructured":"11. Guptill JT, Sanders DB, Evoli A. Anti-MuSK antibody myasthenia gravis: clinical findings and response to treatment in two large cohorts. Muscle Nerve 44: 36-40, 2011."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Tzartos JS, Zisimopoulou P, Rentzos, et al. LRP4 antibodies in serum and CSF from amyotrophic lateral sclerosis patients. Ann Clin Transl Neurol 1: 80-88, 2014.","DOI":"10.1002\/acn3.26"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Suzuki S, Utsugisawa K, Yoshikawa H, et al. Autoimmune targets of heart and skeletal muscles in myasthenia gravis. Arch Neurol 66: 1334-1338, 2009.","DOI":"10.1001\/archneurol.2009.229"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Stergiou C, Lazaridis K, Zouvelou V. Titin antibodies in "seronegative" myasthenia gravis-a new role for an old antigen. J Neuroimmunol 292: 108-115, 2016.","DOI":"10.1016\/j.jneuroim.2016.01.018"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/60\/1\/60_4957-20\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T03:49:11Z","timestamp":1609559351000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/60\/1\/60_4957-20\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.4957-20","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,1]]}}}