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Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients. J Hepatol 28: 930-938, 1998."},{"key":"6","unstructured":"6. Ikeda K, Saitoh S, Koida I, et al. A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis. Hepatology 18: 47-53, 1993."},{"key":"7","unstructured":"7. Degos F, Christidis C, Ganne-Carrie N, et al. Hepatitis C virus related cirrhosis: time to occurrence of hepatocellular carcinoma and death. Gut 47: 131-136, 2000."},{"key":"8","unstructured":"8. Ikeda K, Saitoh S, Arase Y, et al. Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis C: a long term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis. Hepatology 29: 1124-1130, 1999."},{"key":"9","unstructured":"9. Bruno S, Stroffolini T, Colombo M, et al. Sustained virological response to interferon-α is associated with improved outcome in HCV-related cirrhosis: a retrospective study. Hepatology 45: 579-587, 2007."},{"key":"10","unstructured":"10. Watanabe S, Enomoto N, Koike K, et al. Cancer preventive effect of pegylated interferon α-2b plus ribavirin in a real-life clinical setting in Japan: PERFECT interim analysis. Hepatol Res 41: 955-964, 2011."},{"key":"11","unstructured":"11. Mashitani T, Yoshiji H, Yamazaki M, et al. Development of hepatocellular carcinoma in a patient 13 years after sustained virological response to interferon against chronic hepatitis C: a case report. Cases J 2: 18, 2009."},{"key":"12","unstructured":"12. Saito M, Seo Y, Yano Y, et al. Development of a hepatocellular carcinoma in a chronic hepatitis C patient 18 years after achieving a sustained virological response to interferon therapy: case report and literature review. Clin J Gastroenterol 5: 119-126, 2012."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Chiba T, Matsuzaki Y, Abei M, et al. Multivariate analysis of risk factors for hepatocellular carcinoma in patients with hepatitis C virus-related liver cirrhosis. J Gastroenterol 31: 552-558, 1996.","DOI":"10.1007\/BF02355056"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Kasahara A, Hayashi N, Mochizuki K, et al. Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C. Osaka Liver Disease Study Group. Hepatology 27: 1394-1402, 1998.","DOI":"10.1002\/hep.510270529"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Makiyama A, Itoh Y, Kasahara A, et al. Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma after a sustained response to interferon therapy. 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