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Baddour LM, Wilson WR, Bayer AS, et al. Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. Circulation 111: e394-e434, 2005."},{"key":"2","unstructured":"2. Durack DT, Lukes AS, Bright DK. New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service. Am J Med 96: 200-209, 1994."},{"key":"3","unstructured":"3. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing, M100-S21, 2011."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Henry NK, Wilson WR, Geraci JE. Treatment of streptomycin-susceptible enterococcal experimental endocarditis with combinations of penicillin and low- or high-dose streptomycin. Antimicrob Agents Chemother 30: 725-728, 1986.","DOI":"10.1128\/AAC.30.5.725"},{"key":"5","unstructured":"5. Eagle H, Fleischman R, Levy M. \"Continuous\" vs. \"discontinuous\" therapy with penicillin: the effect of the interval between injections on therapeutic efficacy. N Engl J Med 248: 481-488, 1953."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Hughes DW, Frei CR, Maxwell PR, et al. Continuous versus intermittent infusion of oxacillin for treatment of infective endocarditis caused by methicillin-susceptible <i>Staphylococcus aureus<\/i>. Antimicrob Agents Chemother 53: 2014-2019, 2009.","DOI":"10.1128\/AAC.01232-08"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Roberts JA, Webb S, Paterson D, Ho KM, Lipman J. A systematic review on clinical benefits of continuous administration of &beta;-lactam antibiotics. Crit Care Med 37: 2071-2078, 2009.","DOI":"10.1097\/CCM.0b013e3181a0054d"},{"key":"8","unstructured":"8. Buck C, Bertram N, Ackermann T, et al. Pharmacokinetics of piperacillin-tazobactam: intermittent dosing versus continuous infusion. Int J Antimicrob Agents 25: 62-67, 2005."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Lau WK, Mercer D, Itani KM, et al. Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection. Antimicrob Agents Chemother 50: 3556-3561, 2006.","DOI":"10.1128\/AAC.00329-06"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. P&eacute;deboscq S, Dubau B, Frappier S, et al. Comparison of 2 administration protocol (continuous or discontinuous) of a time-dependent antibiotic, Tazocin. Pathol Biol (Paris) 49: 540-547, 2001.","DOI":"10.1016\/S0369-8114(01)00210-3"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Nicolau DP. Pharmacodynamic optimization of beta-lactams in the patient care setting. Crit Care 12 (Suppl 4): S2, 2008.","DOI":"10.1186\/cc6818"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Chain E, Florey HW, Adelaide MB, et al. Penicillin as a chemotherapeutic agent. Lancet 236: 226-228, 1940.","DOI":"10.1016\/S0140-6736(01)08728-1"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Gavald&agrave; J, Torres C, Tenorio C, et al. Efficacy of ampicillin plus ceftriaxone in treatment of experimental endocarditis due to <i>Enterococcus faecalis<\/i> strains highly resistant to aminoglycosides. Antimicrob Agent Chemother 43: 639-646, 1999.","DOI":"10.1128\/AAC.43.3.639"},{"key":"14","unstructured":"14. Gavald&agrave; J, Len O, Mir&oacute; JM, et al. Brief communication: treatment of <i>Enterococcus faecalis<\/i> endocarditis with ampicillin plus ceftriaxone. Ann Intern Med 146: 574-579, 2007."},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Euba G, Lora-Tamayo J, Murillo O, et al. Pilot study of ampicillin-ceftriaxone combination for treatment of orthopedic infections due to <i>Enterococcus faecalis<\/i>. Antimicrob Agents Chemother 53: 4305-4310, 2009.","DOI":"10.1128\/AAC.00444-09"},{"key":"16","unstructured":"16. Geraci JE, Martin WJ. Antibiotic therapy of bacterial endocarditis. VI. Subacute enterococcal endocarditis: clinical, pathologic and therapeutic consideration of 33 cases. Circulation 10: 173-194, 1954."},{"key":"17","unstructured":"17. Zhao X, Drlica K. Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies. Clin Infect Dis 33: S147-S156, 2001."},{"key":"18","unstructured":"18. Zhao X, Drlica K. Restricting the selection of antibiotic-resistant mutants: measurement and potential uses of the mutant selection window. J Infect Dis 185: 561-565, 2002."},{"key":"19","unstructured":"19. Bonow RO, Carabello B, Chatterjee K, et al. ACC\/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients with Valvular Heart Disease). Circulation 114: e84-e231, 2006."},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Kang DH, Kim YJ, Kim SH, et al. Early surgery versus conventional treatment for infective endocarditis. N Engl J Med 28: 2466-2473, 2012.","DOI":"10.1056\/NEJMoa1112843"},{"key":"21","unstructured":"21. Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009). 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