{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T15:12:20Z","timestamp":1781968340166,"version":"3.54.5"},"reference-count":20,"publisher":"Japanese Society of Internal Medicine","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2025,12,1]]},"DOI":"10.2169\/internalmedicine.5358-25","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T18:07:40Z","timestamp":1749060460000},"page":"3433-3437","source":"Crossref","is-referenced-by-count":2,"title":["Exogenous Lipoid Pneumonia Induced by the Excessive Use of Menthol-containing Nasal Inhalers and Subsequent Acute Hypersensitivity Pneumonia Triggered by Domestic Environmental Antigens"],"prefix":"10.2169","volume":"64","author":[{"given":"Yuki","family":"Fukushiro","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Horimasu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kakuhiro","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinjiro","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Masuda","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taku","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Iwamoto","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Ohshimo","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Fujitaka","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noboru","family":"Hattori","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Hiroshima University Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","unstructured":"1. Laughlen GF. Studies on pneumonia following naso-pharyngeal injections of oil. Am J Pathol 1: 407-414, 1925."},{"key":"2","unstructured":"2. Murase K, Noda K, Otaki Y, Yasuda J, Aoki S, Shimizu S. A case of exogenous lipoid pneumonia induced by inhalation of mouse repellent. Nihon Kokyuki Gakkai Zasshi (J Jpn Respir Soc) 2: 466-470, 2013 (in Japanese)."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Baron SE, Haramati LB, Rivera VT. Radiological and clinical findings in acute and chronic exogenous lipoid pneumonia. J Thorac Imaging 18: 217-224, 2003.","DOI":"10.1097\/00005382-200310000-00002"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Spickard A 3rd, Hirschmann JV. Exogenous lipoid pneumonia. Arch Intern Med 154: 686-692, 1994.","DOI":"10.1001\/archinte.1994.00420060122013"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Raghu G, Remy-Jardin M, Richeldi L, et al. Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS\/ERS\/JRS\/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med 205: e18-e47, 2022.","DOI":"10.1164\/rccm.202202-0399ST"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Patel AM, Ryu JH, Reed CE. Hypersensitivity pneumonitis: current concepts and future questions. J Allergy Clin Immunol 108: 661-670, 2001.","DOI":"10.1067\/mai.2001.119570"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Barnes H, Troy L, Lee CT, Sperling A, Strek M, Glaspole I. Hypersensitivity pneumonitis: current concepts in pathogenesis, diagnosis, and treatment. Allergy 77: 442-453, 2022.","DOI":"10.1111\/all.15017"},{"key":"8","doi-asserted-by":"publisher","unstructured":"8. Schroder K, Tschopp J. The inflammasomes. Cell 140: 821-832, 2010.","DOI":"10.1016\/j.cell.2010.01.040"},{"key":"9","doi-asserted-by":"publisher","unstructured":"9. Strowig T, Henao-Mejia J, Elinav E, Flavell R. Inflammasomes in health and disease. Nature 481: 278-286, 2012.","DOI":"10.1038\/nature10759"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. McKee CM, Coll RC. NLRP3 inflammasome priming: a riddle wrapped in a mystery inside an enigma. J Leukoc Biol 108: 937-952, 2020.","DOI":"10.1002\/JLB.3MR0720-513R"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Paik S, Kim JK, Silwal P, Sasakawa C, Jo EK. An update on the regulatory mechanisms of NLRP3 inflammasome activation. Cell Mol Immunol 18: 1141-1160, 2021.","DOI":"10.1038\/s41423-021-00670-3"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Ye WD, Wang HM, Xu ZJ, et al. MCC950 ameliorates acute exogenous lipoid pneumonia induced by sewing machine oil in rats <i>via<\/i> the NF-\u03baB\/NLRP3 inflammasome pathway. In Vivo 37: 2533-2542, 2023.","DOI":"10.21873\/invivo.13361"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Kankkunen P, Teiril\u00e4 L, Rintahaka J, Alenius H, Wolff H, Matikainen S. (1,3)-\u03b2-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages. J Immunol 184: 6335-6342, 2010.","DOI":"10.4049\/jimmunol.0903019"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Reyes de la Rocha S, Cunningham JC, Fox E. Lipoid pneumonia secondary to baby oil aspiration: a case report and review of the literature. Pediatr Emerg Care 1: 74-80, 1985.","DOI":"10.1097\/00006565-198501020-00007"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Bandla HP, Davis SH, Hopkins NE. Lipoid pneumonia: a silent complication of mineral oil aspiration. Pediatrics 103: E19, 1999.","DOI":"10.1542\/peds.103.2.e19"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Weinstein M. First do no harm: the dangers of mineral oil. Paediatr Child Health 6: 129-131, 2001.","DOI":"10.1093\/pch\/6.3.129"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Tilley AE, Walters MS, Shaykhiev R, Crystal RG. Cilia dysfunction in lung disease. Annu Rev Physiol 77: 379-406, 2015.","DOI":"10.1146\/annurev-physiol-021014-071931"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Ghafari Farsani H, Gerami MH, Farsani MN, et al. Effect of different levels of essential oils (Satureja hortensis) in diet on improvement growth, blood biochemical and immunity of angelfish (<i>Pterophyllum scalare<\/i> Schultze, 1823). Nat Prod Res 24: 1-6, 2018.","DOI":"10.1080\/14786419.2018.1434635"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Vazirzadeh A, Dehghan F, Kazemeini R. Changes in growth, blood immune parameters and expression of immune related genes in rainbow trout (<i>Oncorhynchus mykiss<\/i>) in response to diet supplemented with <i>Ducrosia anethifolia<\/i> essential oil. Fish Shellfish Immunol 69: 164-172, 2017.","DOI":"10.1016\/j.fsi.2017.08.022"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Kawai A, Noda M, Hirata H, et al. Lipid nanoparticle with 1,2-Di-O-octadecenyl-3-trimethylammonium-propane as a component lipid confers potent responses of Th1 cells and antibody against vaccine antigen. ACS Nano 18: 16589-16609, 2024.","DOI":"10.1021\/acsnano.4c00278"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/23\/64_5358-25\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T03:27:51Z","timestamp":1764991671000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/64\/23\/64_5358-25\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,1]]},"references-count":20,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.5358-25","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,1]]},"article-number":"5358-25"}}