{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:17:39Z","timestamp":1756383459987},"reference-count":17,"publisher":"Japanese Society of Internal Medicine","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2015]]},"DOI":"10.2169\/internalmedicine.54.3123","type":"journal-article","created":{"date-parts":[[2015,2,28]],"date-time":"2015-02-28T22:21:47Z","timestamp":1425162107000},"page":"445-451","source":"Crossref","is-referenced-by-count":5,"title":["The Level of Bone Marrow WT1 Message is a Useful Marker to Differentiate Myelodysplastic Syndromes with Low Blast Percentage from Cytopenia due to Other Reasons"],"prefix":"10.2169","volume":"54","author":[{"given":"Maki","family":"Baba","sequence":"first","affiliation":[{"name":"Department of Hematology, Unit of Atomic Bomb Disease and Hibakusha Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Hematology, Unit of Atomic Bomb Disease and Hibakusha Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"},{"name":"Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Tsushima","sequence":"additional","affiliation":[{"name":"Department of Hematology, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayaka","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuto","family":"Turuta","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroo","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Hematology, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Sawayama","sequence":"additional","affiliation":[{"name":"Department of Hematology, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Imanishi","sequence":"additional","affiliation":[{"name":"Department of Hematology, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Taguchi","sequence":"additional","affiliation":[{"name":"Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsunori","family":"Yanagihara","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Nagasaki University Hospital, Japan"},{"name":"Department of Laboratory Medicine, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Tomonaga","sequence":"additional","affiliation":[{"name":"Department of Hematology, Unit of Atomic Bomb Disease and Hibakusha Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimeru","family":"Kamihira","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Department of Hematology, Unit of Atomic Bomb Disease and Hibakusha Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan"},{"name":"Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Japan"},{"name":"Department of Hematology, Nagasaki University Hospital, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Bennett JM, Catovsky D, Daniel MT, et al. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 51: 189-199, 1982.","DOI":"10.1111\/j.1365-2141.1982.tb08475.x"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the WHO classification of myeloid neoplasms and acute leukemia, rationale and important changes. Blood 114: 937-951, 2009.","DOI":"10.1182\/blood-2009-03-209262"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Papaemmanuil E, Gerstung M, Malcovati L, et al. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood 122: 3616-3627, 2013.","DOI":"10.1182\/blood-2013-08-518886"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Haferlach T, Nagata Y, Grossmann V, et al. Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Leukemia 28: 241-247, 2014.","DOI":"10.1038\/leu.2013.336"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Yoshida K, Sanada M, Shiraishi Y, et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature 478: 64-69, 2011.","DOI":"10.1038\/nature10496"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Walter MJ, Ding L, Shen D, et al. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. Leukemia 25: 1153-1158, 2011.","DOI":"10.1038\/leu.2011.44"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Langemeijer SM, Kuiper RP, Berends M, et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet 41: 838-842, 2009.","DOI":"10.1038\/ng.391"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Matsuda A, Jinnai I, Miyazaki Y, et al. Proposals for a grading system for diagnostic accuracy of the myelodysplastic syndromes. Clin Leuk 2: 102-106, 2008.","DOI":"10.3816\/CLK.2008.n.012"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Inoue K, Sugiyama H, Ogawa H, et al. WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 84: 3071-3079, 1994.","DOI":"10.1182\/blood.V84.9.3071.bloodjournal8493071"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Miyawaki S, Hatsumi N, Tamaki T, et al. Prognostic potential of detection of WT1 mRNA level in peripheral blood in adult acute myeloid leukemia. Leuk Lymphoma 51: 1855-1861, 2010.","DOI":"10.3109\/10428194.2010.507829"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Ueda Y, Mizutani C, Nannya Y, et al. Clinical evaluation of WT1 mRNA expression levels in peripheral blood and bone marrow in patients with myelodysplastic syndromes. Leuk Lymphoma 54: 1450-1458, 2013.","DOI":"10.3109\/10428194.2012.745074"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 89: 2079-2088, 1997.","DOI":"10.1182\/blood.V89.6.2079"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Greenberg PL, Tuechler H, Schanz J, et al. Revised international prognostic scoring system for myelodysplastic syndromes. Blood 120: 2454-2465, 2012.","DOI":"10.1182\/blood-2012-03-420489"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Valent P, Bain BJ, Bennett JM, et al. Idiopathic cytopenia of undetermined significance (ICUS) and idiopathic dysplasia of uncertain significance (IDUS), and their distinction from low risk MDS. Leuk Res 36: 1-5, 2012.","DOI":"10.1016\/j.leukres.2011.08.016"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Ogawa H, Tamaki H, Ikegame K, et al. The usefulness of monitoring <i>WT1<\/i> gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia. Blood 101: 1698-1704, 2003.","DOI":"10.1182\/blood-2002-06-1831"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Jaiyesimi IA, Friedline JA, Mattson JC, et al. Myelodysplastic syndrome at a large tertiary care community hospital: analysis according to the international prognostic scoring system. Leuk Res 24: 417-426, 2000.","DOI":"10.1016\/S0145-2126(99)00204-0"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Voso MT, Fenu S, Latagliata R, et al. Revised International Prognostic Scoring System (IPSS) predicts survival and leukemic evolution of myelodysplastic syndromes significantly better than IPSS and WHO Prognostic Scoring System: validation by the Gruppo Romano Mielodisplasie Italian Regional Database. J Clin Oncol 31: 2671-2677, 2013.","DOI":"10.1200\/JCO.2012.48.0764"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T11:27:01Z","timestamp":1598786821000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/54\/5\/54_54.3123\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.54.3123","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}