{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T10:36:45Z","timestamp":1792319805627,"version":"4.4.0"},"reference-count":18,"publisher":"Japanese Society of Internal Medicine","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2015]]},"DOI":"10.2169\/internalmedicine.54.3919","type":"journal-article","created":{"date-parts":[[2015,8,14]],"date-time":"2015-08-14T22:04:25Z","timestamp":1439589865000},"page":"1995-1999","source":"Crossref","is-referenced-by-count":8,"title":["Multiple Colon Ulcers with Typical Small Intestinal Lesions Induced by Non-Steroidal Anti-Inflammatory Drugs"],"prefix":"10.2169","volume":"54","author":[{"given":"Momoko","family":"Akashi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeru","family":"Hamashima","sequence":"additional","affiliation":[{"name":"Department of Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Yoshita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sohachi","family":"Nanjo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Mihara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruka","family":"Fujinami","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Kajiura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumu","family":"Hosokawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Lim YJ, Yang CH. Non-steroidal anti-inflammatory drug-induced enteropathy. Clin Endosc 45: 138-144, 2012.","DOI":"10.5946\/ce.2012.45.2.138"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Amano Y, Kushiyama Y, Takahashi Y, Ishihara S, Adachi K, Kinoshita Y. Prevalence of ileo-colonic ulcerative lesions in chronic NSAIDs users. Am J Gastroenterol 99: 1193, 2004.","DOI":"10.1111\/j.1572-0241.2004.30220.x"},{"key":"3","unstructured":"3. Matsumoto T, Iida M, Kurahara K, et al. Clinical and endoscpoic features in patients with nonsteroidal anti-inflammatory drug-induced colopathy. Stomach and Instestine 35: 1147-1158, 2000 (in Japanese, Abstract in English)."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Kurahara K, Matsumoto T, Iida M, Honda K, Yao T, Fujishima M. Clinical and endoscopic features of nonsteroidal anti-inflammatory drug-induced colonic ulcerations. Am J Gastroenterol 96: 473-480, 2001.","DOI":"10.1111\/j.1572-0241.2001.03530.x"},{"key":"5","unstructured":"5. El Hajj I, Hawchar M, Sharara A. NSAID-induced colopathy: case report and review of the literature. J Med Liban 57: 274-276, 2009."},{"key":"6","unstructured":"6. Ueda H, Furuzono M, Matsumoto J, Arima T. A case of hemorrahgic multiple colonic ulcerations associated with nonsteroidal antiinflammatory drugs, successfully treated by endoscopic hemostasis. Gastroenterological Endoscopy 42: 1316-1322, 2000 (in Japanese, Abstract in English)."},{"key":"7","unstructured":"7. Aftab AR, Donnellan F, Zeb F, Kevans D, Cullen G, Courtney G. NSAID-induced colopathy. A case series. J Gastrointestin Liver Dis 19: 89-91, 2010."},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Chan FK, Lanas A, Scheiman J, Berger MF, Nguyen H, Goldstein JL. Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial. Lancet 376: 173-179, 2010.","DOI":"10.1016\/S0140-6736(10)60673-3"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, Vane JR. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci USA 96: 7563-7568, 1999.","DOI":"10.1073\/pnas.96.13.7563"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Wallace JL. Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years. Gastroenterology 112: 1000-1016, 1997.","DOI":"10.1053\/gast.1997.v112.pm9041264"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Perini R, Fiorucci S, Wallace JL. Mechanisms of nonsteroidal anti-inflammatory drug-induced gastrointestinal injury and repair: a window of opportunity for cyclooxygenase-inhibiting nitric oxide donors. Can J Gastroenterol 18: 229-236, 2004.","DOI":"10.1155\/2004\/890585"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Reuter BK, Asfaha S, Buret A, Sharkey KA, Wallace JL. Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2. J Clin Invest 98: 2076-2085, 1996.","DOI":"10.1172\/JCI119013"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Jones MK, Wang H, Peskar BM, et al. Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. Nat Med 5: 1418-1423, 1999.","DOI":"10.1038\/70995"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Silverstein FE, Faich G, Goldstein JL, et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA 284: 1247-1255, 2000.","DOI":"10.1001\/jama.284.10.1247"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Matsumoto T, Nakamura S, Esaki M, et al. Endoscopic features of chronic nonspecific multiple ulcers of the small intestine: comparison with nonsteroidal anti-inflammatory drug-induced enteropathy. Dig Dis Sci 51: 1357-1363, 2006.","DOI":"10.1007\/s10620-006-9080-x"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Argüelles-Arias F, Rodríguez-Oballe J, Duarte-Chang C, et al. Capsule endoscopy in the small bowel Crohn's disease. Gastroenterol Res Pract 2014: 529136, 2014.","DOI":"10.1155\/2014\/529136"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Fujimori S, Seo T, Gudis K, et al. Prevention of nonsteroidal anti-inflammatory drug-induced small-intestinal injury by prostaglandin: a pilot randomized controlled trial evaluated by capsule endoscopy. Gastrointest Endosc 69: 1339-1346, 2009.","DOI":"10.1016\/j.gie.2008.08.017"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Niwa Y, Nakamura M, Ohmiya N, et al. Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: a prospective, randomized, double-blinded, placebo-controlled, cross-over study. J Gastroenterol 43: 270-276, 2008.","DOI":"10.1007\/s00535-007-2155-4"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/54\/16\/54_54.3919\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T11:36:57Z","timestamp":1567078617000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/54\/16\/54_54.3919\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":18,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.54.3919","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}