{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:39:51Z","timestamp":1790095191797,"version":"4.0.1"},"reference-count":32,"publisher":"Japanese Society of Internal Medicine","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2016]]},"DOI":"10.2169\/internalmedicine.55.5275","type":"journal-article","created":{"date-parts":[[2016,2,14]],"date-time":"2016-02-14T22:04:24Z","timestamp":1455487464000},"page":"347-352","source":"Crossref","is-referenced-by-count":48,"title":["A Feasibility Study of Virtual Reality Exercise in Elderly Patients with Hematologic Malignancies Receiving Chemotherapy"],"prefix":"10.2169","volume":"55","author":[{"given":"Kenji","family":"Tsuda","sequence":"first","affiliation":[{"name":"Division of Hematology and Rheumatology, Teikyo University Chiba Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuaki","family":"Sudo","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Teikyo University Chiba Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goro","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Tsukuba Memorial Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makiko","family":"Takai","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Tokyo Metropolitan Rehabilitation Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuo","family":"Itokawa","sequence":"additional","affiliation":[{"name":"Division of Hematology and Rheumatology, Teikyo University Chiba Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Isshiki","sequence":"additional","affiliation":[{"name":"Division of Hematology and Rheumatology, Teikyo University Chiba Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Takei","sequence":"additional","affiliation":[{"name":"Division of Hematology and Rheumatology, Teikyo University Chiba Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Tanimoto","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Navitas Clinic, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsunehiko","family":"Komatsu","sequence":"additional","affiliation":[{"name":"Division of Hematology and Rheumatology, Teikyo University Chiba Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Schmitz KH, Courneya KS, Matthews C, et al. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc 42: 1409-1426, 2010.","DOI":"10.1249\/MSS.0b013e3181e0c112"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Courneya KS, Segal RJ, Reid RD, et al. Three independent factors predicted adherence in a randomized controlled trial of resistance exercise training among prostate cancer survivors. J Clin Epidemiol 57: 571-579, 2004.","DOI":"10.1016\/j.jclinepi.2003.11.010"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Courneya KS, Segal RJ, Mackey JR, et al. Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: a multicenter randomized controlled trial. J Clin Oncol 25: 4396-4404, 2007.","DOI":"10.1200\/JCO.2006.08.2024"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Adamsen L, Quist M, Andersen C, et al. Effect of a multimodal high intensity exercise intervention in cancer patients undergoing chemotherapy: randomised controlled trial. BMJ 2009: 2009.","DOI":"10.1136\/bmj.b3410"},{"key":"5","unstructured":"5. Mihalko SL, Klepin HD, Stott K, et al. Exercise for older adult inpatients with acute myelogenous leukemia: A pilot study. J Geriatr Oncol 2: 11-17, 2011."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Alibhai SMH, O'Neill S, Fisher-Schlombs K, et al. A clinical trial of supervised exercise for adult inpatients with acute myeloid leukemia (AML) undergoing induction chemotherapy. Leuk Res 36: 1255-1261, 2012.","DOI":"10.1016\/j.leukres.2012.05.016"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Saposnik G, Teasell R, Mamdani M, et al. Effectiveness of virtual reality using Wii gaming technology in stroke rehabilitation: a pilot randomized clinical trial and proof of principle. Stroke 41: 1477-1484, 2010.","DOI":"10.1161\/STROKEAHA.110.584979"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Deutsch JE, Borbely M, Filler J, et al. Use of a low-cost, commercially available gaming console (Wii) for rehabilitation of an adolescent with cerebral palsy. Phys Ther 88: 1196-1207, 2008.","DOI":"10.2522\/ptj.20080062"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Yohannan SK, Tufaro PA, Hunter H, et al. The utilization of Nintendo<sup>&reg;<\/sup> Wii<sup>TM<\/sup> during burn rehabilitation: a pilot study. J Burn Care Res 33: 36-45, 2011.","DOI":"10.1097\/BCR.0b013e318234d8ef"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Hoffman AJ, Brintnall RA, Brown JK, et al. Virtual reality bringing a new reality to postthoracotomy lung cancer patients via a home-based exercise intervention targeting fatigue while undergoing adjuvant treatment. Cancer Nurs 37: 23-33, 2014.","DOI":"10.1097\/NCC.0b013e318278d52f"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Chan TC, Chan F, Shea YF, et al. Interactive virtual reality Wii in geriatric day hospital: a study to assess its feasibility, acceptability and efficacy. Geriatr Gerontol Int 12: 714-721, 2012.","DOI":"10.1111\/j.1447-0594.2012.00848.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Williams MA, Soiza RL, Jenkinson AM, et al. Exercising with Computers in Later Life (EXCELL) - pilot and feasibility study of the acceptability of the Nintendo<sup>&reg;<\/sup> WiiFit in community-dwelling fallers. BMC Res Notes 3: 238, 2010.","DOI":"10.1186\/1756-0500-3-238"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Yong Joo L, Soon Yin T, Xu D, et al. A feasibility study using interactive commercial off-the-shelf computer gaming in upper limb rehabilitation in patients after stroke. J Rehabil Med 42: 437-441, 2010.","DOI":"10.2340\/16501977-0528"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Pompeu JE, Mendes FA, Silva KG, et al. Effect of Nintendo Wii<sup>TM<\/sup>-based motor and cognitive training on activities of daily living in patients with Parkinson's disease: a randomised clinical trial. Physiotherapy 98: 196-204, 2012.","DOI":"10.1016\/j.physio.2012.06.004"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Taylor MJ, McCormick D, Shawis T, et al. Activity-promoting gaming systems in exercise and rehabilitation. J Rehabil Res Dev 48: 1171-1186, 2011.","DOI":"10.1682\/JRRD.2010.09.0171"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Wade DT, Collin C. The Barthel ADL Index: a standard measure of physical disability? Int Disabil Stud 10: 64-67, 1988.","DOI":"10.3109\/09638288809164105"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Gosman-Hedstr&ouml;m G, Svensson E. Parallel reliability of the functional independence measure and the Barthel ADL index. Disabil Rehabil 10: 702-715, 2000.","DOI":"10.1080\/09638280050191972"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Gocha Marchese V, Chiarello LA, Lange BJ. Strength and functional mobility in children with acute lymphoblastic leukemia. Med Pediatr Oncol 40: 230-232, 2003.","DOI":"10.1002\/mpo.10266"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Shumway-Cook A, Brauer S, Woollacott M. Predicting the probability for falls in community-dwelling older adults using the Timed Up &amp; Go Test. Phys Ther 80: 896-903, 2000.","DOI":"10.1093\/ptj\/80.9.896"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Terluin B, Brouwers EP, van Marwijk HW, et al. Detecting depressive and anxiety disorders in distressed patients in primary care; comparative diagnostic accuracy of the Four-Dimensional Symptom Questionnaire (4DSQ) and the Hospital Anxiety and Depression Scale (HADS). BMC Fam Pract 10: 2009.","DOI":"10.1186\/1471-2296-10-58"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Kugaya A, Akechi T, Okuyama T, et al. Screening for psychological distress in Japanese cancer patients. Jpn J Clin Oncol 28: 333-338, 1998.","DOI":"10.1093\/jjco\/28.5.333"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Eley KA. A Wii fracture. N Engl J Med 362: 473-474, 2010.","DOI":"10.1056\/NEJMc0909544"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Peek AC, Ibrahim T, Abunasra H, et al. White-out from a Wii: traumatic haemothorax sustained playing Nintendo Wii. Ann R Coll Surg Engl 90: W9-W10, 2008.","DOI":"10.1308\/147870808X303100"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Klepin HD, Danhauer SC, Tooze JA, et al. Exercise for older adult inpatients with acute myelogenous leukemia: A pilot study. J Geriatr Oncol 2: 11-17, 2011.","DOI":"10.1016\/j.jgo.2010.10.004"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Elter T, Stipanov M, Heuser E, et al. Is physical exercise possible in patients with critical cytopenia undergoing intensive chemotherapy for acute leukaemia or aggressive lymphoma? Int J Hematol 90: 199-204, 2009.","DOI":"10.1007\/s12185-009-0376-4"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Courneya KS, Sellar CM, Stevinson C, et al. Randomized controlled trial of the effects of aerobic exercise on physical functioning and quality of life in lymphoma patients. J Clin Oncol 27: 4605-4612, 2009.","DOI":"10.1200\/JCO.2008.20.0634"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Chang PH, Lai YH, Shun SC, et al. Effects of a walking intervention on fatigue-related experiences of hospitalized acute myelogenous leukemia patients undergoing chemotherapy: a randomized controlled trial. J Pain Symptom Manage 35: 524-534, 2008.","DOI":"10.1016\/j.jpainsymman.2007.06.013"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Jang SH, You SH, Hallett M, et al. Cortical reorganization and associated functional motor recovery after virtual reality in patients with chronic stroke: an experimenter-blind preliminary study. Arch Phys Med Rehabil 86: 2218-2223, 2005.","DOI":"10.1016\/j.apmr.2005.04.015"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Broeren J, Rydmark M, Sunnerhagen KS. Virtual reality and haptics as a training device for movement rehabilitation after stroke: a single-case study. Arch Phys Med Rehabil 85: 1247-1250, 2004.","DOI":"10.1016\/j.apmr.2003.09.020"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Kim J, Son J, Ko N, et al. Unsupervised virtual reality-based exercise program improves hip muscle strength and balance control in older adults: a pilot study. Arch Phys Med Rehabil 94: 937-943, 2013.","DOI":"10.1016\/j.apmr.2012.12.010"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Yuen HK, Holthaus K, Kamen DL, et al. Using Wii Fit to reduce fatigue among African American women with systemic lupus erythematosus: A pilot study. Lupus 20: 1293-1299, 2011.","DOI":"10.1177\/0961203311412098"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Courneya KS, Stevinson C, McNeely ML, et al. Predictors of adherence to supervised exercise in lymphoma patients participating in a randomized controlled trial. Ann Behav Med 40: 30-39, 2010.","DOI":"10.1007\/s12160-010-9205-5"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/55\/4\/55_55.5275\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T03:58:03Z","timestamp":1654315083000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/55\/4\/55_55.5275\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.55.5275","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}