{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:32:07Z","timestamp":1770222727127,"version":"3.49.0"},"reference-count":24,"publisher":"Japanese Society of Internal Medicine","issue":"17","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern. Med."],"published-print":{"date-parts":[[2016]]},"DOI":"10.2169\/internalmedicine.55.6395","type":"journal-article","created":{"date-parts":[[2016,8,31]],"date-time":"2016-08-31T22:17:27Z","timestamp":1472681847000},"page":"2463-2467","source":"Crossref","is-referenced-by-count":13,"title":["Desmoplastic Small Round Cell Tumor of the Pleura Successfully Treated with a Lower Dose of Pazopanib"],"prefix":"10.2169","volume":"55","author":[{"given":"Tatsuyoshi","family":"Ikeue","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Japanese Red Cross Wakayama Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issei","family":"Ohi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Japanese Red Cross Wakayama Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Japanese Red Cross Wakayama Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akari","family":"Fukao","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Japanese Red Cross Wakayama Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Terashita","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Japanese Red Cross Wakayama Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadao","family":"Horikawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Japanese Red Cross Wakayama Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takakazu","family":"Sugita","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Japanese Red Cross Wakayama Medical Center, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"962","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Gerald WL, Rosai J. Case 2. Desmoplastic small cell tumor with divergent differentiation. Pediatr Pathol 9: 177-183, 1989.","DOI":"10.3109\/15513818909022347"},{"key":"2","unstructured":"2. Antonescu CR, Ladanyi M. Desmoplastic small round cell tumour. In: WHO Classification of Tumours of Soft Tissue and Bone. 4th ed. Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F, Eds. WHO Press, Geneva, 2013: 225-227."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Gerald WL, Miller HK, Battifora H, Miettinen M, Silva EG, Rosai J. Intra-abdominal desmoplastic small round-cell tumor. Report of 19 cases of a distinctive type of high-grade polyphenotypic malignancy affecting young individuals. Am J Surg Pathol 15: 499-513, 1991.","DOI":"10.1097\/00000478-199106000-00001"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Dufresne A, Cassier P, Couraud L, et al. Desmoplastic small round cell tumor: current management and recent findings. Sarcoma 2012: 714986, 2012.","DOI":"10.1155\/2012\/714986"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Kushner BH, LaQuaglia MP, Wollner N, et al. Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy. J Clin Oncol 14: 1526-1531, 1996.","DOI":"10.1200\/JCO.1996.14.5.1526"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Lal DR, Su WT, Wolden SL, Loh KC, Modak S, La Quaglia MP. Results of multimodal treatment for desmoplastic small round cell tumors. J Pediatr Surg 40: 251-255, 2005.","DOI":"10.1016\/j.jpedsurg.2004.09.046"},{"key":"7","unstructured":"7. Italiano A, Kind M, Cioffi A, Maki RG, Bui B. Clinical activity of sunitinib in patients with advanced desmoplastic round cell tumor: a case series. Target Oncol 8: 211-213, 2013."},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Frezza AM, Benson C, Judson IR, et al. Pazopanib in advanced desmoplastic small round cell tumours: a multi-institutional experience. Clin Sarcoma Res 4: 7, 2014.","DOI":"10.1186\/2045-3329-4-7"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Worch J, Cyrus J, Goldsby R, Matthay KK, Neuhaus J, DuBois SG. Racial differences in the incidence of mesenchymal tumors associated with EWSR1 translocation. Cancer Epidemiol Biomarkers Prev 20: 449-453, 2011.","DOI":"10.1158\/1055-9965.EPI-10-1170"},{"key":"10","unstructured":"10. Bian Y, Jordan AG, Rupp M, Cohn H, McLaughlin CJ, Miettinen M. Effusion cytology of desmoplastic small round cell tumor of the pleura. A case report. Acta Cytol 37: 77-82, 1993."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Parkash V, Gerald WL, Parma A, Miettinen M, Rosai J. Desmoplastic small round cell tumor of the pleura. Am J Surg Pathol 19: 659-665, 1995.","DOI":"10.1097\/00000478-199506000-00006"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Karavitakis EM, Moschovi M, Stefanaki K, et al. Desmoplastic small round cell tumor of the pleura. Pediatr Blood Cancer 49: 335-338, 2007.","DOI":"10.1002\/pbc.20762"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Jian Z, Shaohong H, Wenzhao Z, Lijia G. Misdiagnosed desmoplastic small round cell tumor of the pleura: case report and literature review. J Formos Med Assoc 113: 60-61, 2014.","DOI":"10.1016\/j.jfma.2011.12.002"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Wong HH, Hatcher HM, Benson C, et al. Desmoplastic small round cell tumour: characteristics and prognostic factors of 41 patients and review of the literature. Clin Sarcoma Res 3: 14, 2013.","DOI":"10.1186\/2045-3329-3-14"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Hattori Y, Yoshida A, Sasaki N, Shibuki Y, Tamura K, Tsuta K. Desmoplastic small round cell tumor with sphere-like clusters mimicking adenocarcinoma. Diagn Cytopathol 43: 214-217, 2015.","DOI":"10.1002\/dc.23174"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Rahman NM, Ali NJ, Brown G, et al. Local anaesthetic thoracoscopy: British Thoracic Society Pleural Disease Guideline 2010. Thorax 65: ii54-ii60, 2010.","DOI":"10.1136\/thx.2010.137018"},{"key":"17","unstructured":"17. Froberg K, Brown RE, Gaylord H, Manivel C. Intra-abdominal desmoplastic small round cell tumor: immunohistochemical evidence for up-regulation of autocrine and paracrine growth factors. Ann Clin Lab Sci 29: 78-85, 1999."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Lee SB, Kolquist KA, Nichols K, et al. The EWS-WT1 translocation product induces <i>PDGFA<\/i> in desmoplastic small round-cell tumour. Nat Genet 17: 309-313, 1997.","DOI":"10.1038\/ng1197-309"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Zhang PJ, Goldblum JR, Pawel BR, Pasha TL, Fisher C, Barr FG. PDGF-A, PDGF-R\u03b2, TGF\u03b23 and bone morphogenic protein-4 in desmoplastic small round cell tumors with <i>EWS-WT1<\/i> gene fusion product and their role in stromal desmoplasia: an immunohistochemical study. Mod Pathol 18: 382-387, 2005.","DOI":"10.1038\/modpathol.3800264"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Magnan HD, Chou T, LaQuaglia MP, Gerald W, Ladanyi M, Merchant MS. Elevated expression of VEGFR-2 and VEGFA in desmoplastic small cell round cell tumor (DSRCT) and activity of bevacizumab and irrinotecan in a xenograft model of DSRCT. J Clin Oncol 27: 15s 10016, 2009 (abstract).","DOI":"10.1200\/jco.2009.27.15_suppl.10016"},{"key":"21","unstructured":"21. National Library of Medicine (NLM) at the National Institutes of Health (NIH). ClinicalTrials.gov [Internet]. [cited 2015 Aug. 1]. Available from: https:\/\/clinicaltrials.gov\/ct2\/show\/NCT01189643"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Italiano A, Kind M, Cioffi A, Maki RG, Bui B. Clinical activity of sunitinib in patients with advanced desmoplastic round cell tumor: a case series. Target Oncol 8: 211-213, 2013.","DOI":"10.1007\/s11523-012-0251-8"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Tap WD, Demetri G, Barnette P, et al. Phase II study of ganitumab, a fully human anti-type-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors. J Clin Oncol 30: 1849-1856, 2012.","DOI":"10.1200\/JCO.2011.37.2359"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Naing A, LoRusso P, Fu S, et al. Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing&apos;s sarcoma family tumors. Clin Cancer Res 18: 2625-2631, 2012.","DOI":"10.1158\/1078-0432.CCR-12-0061"}],"container-title":["Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/55\/17\/55_55.6395\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T17:47:15Z","timestamp":1601056035000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/55\/17\/55_55.6395\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":24,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.2169\/internalmedicine.55.6395","relation":{},"ISSN":["0918-2918","1349-7235"],"issn-type":[{"value":"0918-2918","type":"print"},{"value":"1349-7235","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}